The role of chelators in preventing biofilm formation and catheter-related bloodstream infections

Issam I. Raad, Xiang Fang, Xavier M. Keutgen, Ying Jiang, Robert Sherertz, Ray Hachem

Research output: Contribution to journalReview articlepeer-review

94 Scopus citations

Abstract

It is suggested that the addition of chelators such as ethylenediamine- tetraacetic acid and citrate to antimicrobial lock solutions provides an innovative and superior alternative to heparin lock solution in the prevention and treatment of catheter-related bloodstream infections.

Original languageEnglish (US)
Pages (from-to)385-392
Number of pages8
JournalCurrent opinion in infectious diseases
Volume21
Issue number4
DOIs
StatePublished - Aug 2008

Keywords

  • Antimicrobial lock solution
  • Biofilm
  • Catheter-related bloodstream infection
  • Chelator
  • Metal iron

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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