The role of surgery in patients with advanced gynaecological cancers participating in phase I clinical trials

J. Vitfell-Pedersen, T. A. Yap, V. Moreno, R. D. Baird, A. Z. Khan, D. P.J. Barton, S. B. Kaye

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: While gynaecological cancer patients who participate in Phase I clinical trials are not routinely considered for elective surgery because of a short life expectancy, this should not be overlooked in carefully selected responding patients. Methods/Results: We describe two cases of patients with different gynaecological cancers, who received treatment within separate phase I trials, and who then proceeded to surgical resection of their cancers, resulting in complete remission. Conclusion: Surgery, when feasible, should be taken into consideration as a potential management option, even when patients are receiving treatment within a phase I trial.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
JournalEuropean Journal of Gynaecological Oncology
Volume33
Issue number2
StatePublished - May 22 2012
Externally publishedYes

Keywords

  • Gynaecological cancers
  • Phase I trial
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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