The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

J. R.H. Tame; S. H. Sleigh; A. J. Wilkinson; J. E. Ladbury

doi:10.1038/nsb1296-998

The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

J. R.H. Tame, S. H. Sleigh, A. J. Wilkinson, J. E. Ladbury

Research output: Contribution to journal › Article › peer-review

129 Scopus citations

Abstract

Buried water molecules play a pivotal structural and energetic role in mediating interactions between a bacterial oligopeptide transporter protein and its ligands.

Original language	English (US)
Pages (from-to)	998-1001
Number of pages	4
Journal	Nature Structural Biology
Volume	3
Issue number	12
DOIs	https://doi.org/10.1038/nsb1296-998
State	Published - 1996

ASJC Scopus subject areas

Structural Biology
Biochemistry
Genetics

Access to Document

10.1038/nsb1296-998

Cite this

@article{16046c259af94482a14cfb9901333c59,

title = "The role of water in sequence-independent ligand binding by an oligopeptide transporter protein",

abstract = "Buried water molecules play a pivotal structural and energetic role in mediating interactions between a bacterial oligopeptide transporter protein and its ligands.",

author = "Tame, {J. R.H.} and Sleigh, {S. H.} and Wilkinson, {A. J.} and Ladbury, {J. E.}",

year = "1996",

doi = "10.1038/nsb1296-998",

language = "English (US)",

volume = "3",

pages = "998--1001",

journal = "Nature Structural Biology",

issn = "1072-8368",

publisher = "Nature Publishing Group",

number = "12",

}

TY - JOUR

T1 - The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

AU - Tame, J. R.H.

AU - Sleigh, S. H.

AU - Wilkinson, A. J.

AU - Ladbury, J. E.

PY - 1996

Y1 - 1996

N2 - Buried water molecules play a pivotal structural and energetic role in mediating interactions between a bacterial oligopeptide transporter protein and its ligands.

AB - Buried water molecules play a pivotal structural and energetic role in mediating interactions between a bacterial oligopeptide transporter protein and its ligands.

UR - http://www.scopus.com/inward/record.url?scp=0030471364&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030471364&partnerID=8YFLogxK

U2 - 10.1038/nsb1296-998

DO - 10.1038/nsb1296-998

M3 - Article

C2 - 8946852

AN - SCOPUS:0030471364

SN - 1072-8368

VL - 3

SP - 998

EP - 1001

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 12

ER -

The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this