The single-cell assay in cell-mediated cytotoxicity

Benjamin Bonavida; Thomas P. Bradley; Elizabeth A. Grimm

doi:10.1016/0167-5699(83)90081-6

The single-cell assay in cell-mediated cytotoxicity

Benjamin Bonavida, Thomas P. Bradley, Elizabeth A. Grimm

Melanoma Medical Oncology

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

Studies on the humoral antibody response were greatly advanced by the introduction in 1963 of the Jerne plaque assay which permitted direct enumeration of individual antibody-producing plasma cells¹. Studies of cellular cytotoxicity were limited until recently to the examination of whole populations of effector cells². Here, Benjamin Bonavida and his colleagues describe an assay in agarose which allows the study of single cytotoxic cells^3-5.

Original language	English (US)
Pages (from-to)	196-200
Number of pages	5
Journal	Immunology Today
Volume	4
Issue number	7
DOIs	https://doi.org/10.1016/0167-5699(83)90081-6
State	Published - Jul 1983

ASJC Scopus subject areas

Immunology

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10.1016/0167-5699(83)90081-6

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title = "The single-cell assay in cell-mediated cytotoxicity",

abstract = "Studies on the humoral antibody response were greatly advanced by the introduction in 1963 of the Jerne plaque assay which permitted direct enumeration of individual antibody-producing plasma cells1. Studies of cellular cytotoxicity were limited until recently to the examination of whole populations of effector cells2. Here, Benjamin Bonavida and his colleagues describe an assay in agarose which allows the study of single cytotoxic cells3-5.",

author = "Benjamin Bonavida and Bradley, {Thomas P.} and Grimm, {Elizabeth A.}",

year = "1983",

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T1 - The single-cell assay in cell-mediated cytotoxicity

AU - Bonavida, Benjamin

AU - Bradley, Thomas P.

AU - Grimm, Elizabeth A.

PY - 1983/7

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N2 - Studies on the humoral antibody response were greatly advanced by the introduction in 1963 of the Jerne plaque assay which permitted direct enumeration of individual antibody-producing plasma cells1. Studies of cellular cytotoxicity were limited until recently to the examination of whole populations of effector cells2. Here, Benjamin Bonavida and his colleagues describe an assay in agarose which allows the study of single cytotoxic cells3-5.

AB - Studies on the humoral antibody response were greatly advanced by the introduction in 1963 of the Jerne plaque assay which permitted direct enumeration of individual antibody-producing plasma cells1. Studies of cellular cytotoxicity were limited until recently to the examination of whole populations of effector cells2. Here, Benjamin Bonavida and his colleagues describe an assay in agarose which allows the study of single cytotoxic cells3-5.

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M3 - Review article

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JO - Immunology Today

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The single-cell assay in cell-mediated cytotoxicity

Abstract

ASJC Scopus subject areas

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