The Superior Anticancer Effect of Reactive Oxygen Species-Responsive Paclitaxel Nanoparticles is Mediated Through Autophagic Cell Death

Engineering & Materials Science

• Reactive oxygen species 100%
• Cell death 83%
• Nanoparticles 55%
• Fluorescence 42%
• Tumors 38%
• Cells 36%
• Oncology 25%
• Polyethylene glycols 24%
• Assays 21%
• Solubility 20%
• Proteins 17%

Medicine & Life Sciences

• Autophagic Cell Death 81%
• Paclitaxel 57%
• Nanoparticles 50%
• Reactive Oxygen Species 45%
• 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000) 21%
• Autophagy 11%
• Stomach Neoplasms 6%
• Fluorescence 6%
• polycaprolactone 5%
• Beclin-1 5%
• Ethylene Glycol 4%
• Tumor Cell Line 4%
• Solubility 4%
• Antineoplastic Agents 3%
• Stomach 2%
• Western Blotting 2%
• Staining and Labeling 2%
• Neoplasms 2%
• Pharmaceutical Preparations 1%
• Proteins 1%

Chemistry

• Cell Death 60%
• Nanoparticle 28%
• Dioxygen 27%
• Autophagy Inhibitor 17%
• Antineoplastic Agent 16%
• P62 15%
• Clonogenic 14%
• Fluorescence 10%
• Poly(ethylene Glycol) 7%
• Dose 7%
• Solubility 5%
• Protein 3%
• Application 2%