TY - JOUR
T1 - Thymic carcinoma, Part 2
T2 - A clinicopathologic correlation of 33 cases with a proposed staging system
AU - Weissferdt, Annikka
AU - Moran, Cesar A.
PY - 2012/7
Y1 - 2012/7
N2 - Thymic carcinomas are rare neoplasms. Accordingly, no robust staging system exists for these tumors. Herein 33 cases of thymic carcinoma are presented with emphasis on staging, follow-up, and usefulness of prior staging systems. All of the cases shared similar clinical, surgical, and pathologic features, which makes them suitable for appropriate staging. Based on our experience, a novel 3-tier staging schema is presented. According to our proposed schema, 7 patients had stage I tumors, 11 had stage II tumors, and 15 had stage III tumors at the time of resection. Follow-up revealed that 19 patients were alive (mean follow-up, 57 months) and 14 patients had died (mean survival, 44 months). The survival curves obtained using our proposed staging system showed significant differences between the individual stages contrary to those obtained using prior staging systems. Our proposed schema seems to correlate well with survival and seems to be more practical than prior systems.
AB - Thymic carcinomas are rare neoplasms. Accordingly, no robust staging system exists for these tumors. Herein 33 cases of thymic carcinoma are presented with emphasis on staging, follow-up, and usefulness of prior staging systems. All of the cases shared similar clinical, surgical, and pathologic features, which makes them suitable for appropriate staging. Based on our experience, a novel 3-tier staging schema is presented. According to our proposed schema, 7 patients had stage I tumors, 11 had stage II tumors, and 15 had stage III tumors at the time of resection. Follow-up revealed that 19 patients were alive (mean follow-up, 57 months) and 14 patients had died (mean survival, 44 months). The survival curves obtained using our proposed staging system showed significant differences between the individual stages contrary to those obtained using prior staging systems. Our proposed schema seems to correlate well with survival and seems to be more practical than prior systems.
KW - Masaoka staging system
KW - Mediastinum
KW - Staging system
KW - Thymic carcinoma
KW - Thymus
UR - http://www.scopus.com/inward/record.url?scp=84864261841&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864261841&partnerID=8YFLogxK
U2 - 10.1309/AJCPLF3XAT0OHADV
DO - 10.1309/AJCPLF3XAT0OHADV
M3 - Article
C2 - 22706866
AN - SCOPUS:84864261841
SN - 0002-9173
VL - 138
SP - 115
EP - 121
JO - American journal of clinical pathology
JF - American journal of clinical pathology
IS - 1
ER -