Thyroid cancers II: Medullary, anaplastic, lymphoma, sarcoma, squamous cell

J. R. Austin, A. K. El-Naggar, H. Goepfert

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

Medullary thyroid carcinoma in both sporadic and familial forms is a curable disease if detected early and treated by the proper surgery. The advent of genetic screening for the RET protooncogene portends great promise in the earlier diagnosis and treatment of familial forms of MTC. New chemotherapy protocols have produced some tumor regression in patients with metastatic MTC. Improved use of Adriamycin and hyperfractionated radiotherapy combined with debulking procedures has prolonged survival in anaplastic thyroid cancer. Thyroid gland lymphoma, if diagnosed early and treated by combined chemoradiotherapy, carries a good prognosis for survival. The best treatment for thyroid sarcomas and SCC of the thyroid is early diagnosis and aggressive surgery combined with radiotherapy.

Original languageEnglish (US)
Pages (from-to)611-627
Number of pages17
JournalOtolaryngologic Clinics of North America
Volume29
Issue number4
StatePublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology

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