Thyroid carcinoma metastasizing to the submandibular gland: Sonographic findings

Brandon T. Golant, Anneliese Velez-Perez, Savitri Krishnamurthy, Ming Guo, Shima Mousavi, Mimi I. Hu, Jeena M. Varghese, Mark E. Zafereo, James M. Debnam

Research output: Contribution to journalArticlepeer-review


Metastases to the submandibular gland are extremely rare; a literature search retuned only three previously reported cases from a thyroid gland primary site. Herein, we report two cases of metastatic thyroid carcinoma to the submandibular gland in a 64-year-old woman with PTC and a 70-year-old-woman with medullary thyroid carcinoma (MTC). The metastases were identified on CT and PET/CT in one case and on CT in the other case, but both were diagnosed with ultrasound-guided fine-needle aspiration. Our cases highlight that while rare, both PTC and MTC can metastasize to the submandibular gland.

Original languageEnglish (US)
Pages (from-to)227-230
Number of pages4
JournalJournal of Clinical Ultrasound
Issue number4
StatePublished - May 1 2020


  • medullary thyroid carcinoma
  • papillary thyroid carcinoma
  • submandibular gland, metastases, ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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