TY - JOUR
T1 - Translating energy balance research from the bench to the clinic to the community
T2 - Parallel animal-human studies in cancer
AU - Garcia, Miriam B.
AU - Schadler, Keri L.
AU - Chandra, Joya
AU - Clinton, Steven K.
AU - Courneya, Kerry S.
AU - Cruz-Monserrate, Zobeida
AU - Daniel, Carrie R.
AU - Dannenberg, Andrew J.
AU - Demark-Wahnefried, Wendy
AU - Dewhirst, Mark W.
AU - Fabian, Carol J.
AU - Hursting, Stephen D.
AU - Irwin, Melinda L.
AU - Iyengar, Neil M.
AU - McQuade, Jennifer L.
AU - Schmitz, Kathryn H.
AU - Basen-Engquist, Karen
N1 - Publisher Copyright:
© 2023 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer, held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship.
AB - Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer, held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship.
KW - body composition
KW - cancer
KW - cancer survivorship
KW - diet
KW - exercise
KW - nutrition
KW - translational research
UR - http://www.scopus.com/inward/record.url?scp=85148571242&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85148571242&partnerID=8YFLogxK
U2 - 10.3322/caac.21773
DO - 10.3322/caac.21773
M3 - Review article
C2 - 36825928
AN - SCOPUS:85148571242
SN - 0007-9235
VL - 73
SP - 425
EP - 442
JO - CA Cancer Journal for Clinicians
JF - CA Cancer Journal for Clinicians
IS - 4
ER -