Turning reciprocal feedback regulation into combination therapy

Timothy C. Thompson

doi:10.1016/j.ccr.2011.05.022

Turning reciprocal feedback regulation into combination therapy

Timothy C. Thompson

Genitourinary Medical Oncology

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.

Original language	English (US)
Pages (from-to)	697-699
Number of pages	3
Journal	Cancer cell
Volume	19
Issue number	6
DOIs	https://doi.org/10.1016/j.ccr.2011.05.022
State	Published - Jun 14 2011

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2011.05.022

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title = "Turning reciprocal feedback regulation into combination therapy",

abstract = "Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.",

author = "Thompson, {Timothy C.}",

year = "2011",

month = jun,

day = "14",

doi = "10.1016/j.ccr.2011.05.022",

language = "English (US)",

volume = "19",

pages = "697--699",

journal = "Cancer cell",

issn = "1535-6108",

publisher = "Cell Press",

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T1 - Turning reciprocal feedback regulation into combination therapy

AU - Thompson, Timothy C.

PY - 2011/6/14

Y1 - 2011/6/14

N2 - Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.

AB - Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.

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U2 - 10.1016/j.ccr.2011.05.022

DO - 10.1016/j.ccr.2011.05.022

M3 - Short survey

C2 - 21665144

AN - SCOPUS:79958726497

SN - 1535-6108

VL - 19

SP - 697

EP - 699

JO - Cancer cell

JF - Cancer cell

IS - 6

ER -

Turning reciprocal feedback regulation into combination therapy

Abstract

ASJC Scopus subject areas

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