TY - CHAP
T1 - Two-Stage Hepatectomy for Bilateral Colorectal Liver Metastases
T2 - Experience of MD Anderson Cancer Center
AU - Lillemoe, Heather A.
AU - Nishioka, Yujiro
AU - Maki, Harufumi
AU - Vauthey, Jean Nicolas
N1 - Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Historically, most patients presenting with bilateral colorectal liver metastases were determined to be unresectable. However, with perioperative advancements over time and novel technical approaches to liver resection, the 5-year overall survival rates for this group now approach 50%. The two-stage hepatectomy approach entails initial tumor debulking followed by time for interval growth of the future liver remnant and then final curative resection. This chapter will discuss the approach to two-stage hepatectomy at MD Anderson Cancer Center, including a recently described fast-track option. We will explore outcomes after two-stage hepatectomy and future areas for investigation.
AB - Historically, most patients presenting with bilateral colorectal liver metastases were determined to be unresectable. However, with perioperative advancements over time and novel technical approaches to liver resection, the 5-year overall survival rates for this group now approach 50%. The two-stage hepatectomy approach entails initial tumor debulking followed by time for interval growth of the future liver remnant and then final curative resection. This chapter will discuss the approach to two-stage hepatectomy at MD Anderson Cancer Center, including a recently described fast-track option. We will explore outcomes after two-stage hepatectomy and future areas for investigation.
KW - Bilateral colorectal liver metastases
KW - Future liver remnant
KW - Genetic sequencing
KW - Portal vein embolization
KW - Two-stage hepatectomy
UR - http://www.scopus.com/inward/record.url?scp=85159012835&partnerID=8YFLogxK
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U2 - 10.1007/978-3-031-09323-4_7
DO - 10.1007/978-3-031-09323-4_7
M3 - Chapter
AN - SCOPUS:85159012835
SN - 9783031093227
SP - 49
EP - 55
BT - Colorectal Liver Metastasis
PB - Springer International Publishing
ER -