@article{4d1969bfbc8d42abac6dfca1b1bb265e,
title = "Two-year prevalence of dysphagia and related outcomes in head and neck cancer survivors: An updated SEER-Medicare analysis",
abstract = "Background: The aim of the study was to examine prevalence of dysphagia at the population level in head and neck cancer (HNC) survivors. Methods: Surveillance, Epidemiology, and End Results-Medicare claims among 16 194 patients with HNC (2002-2011) were analyzed to estimate 2-year prevalence of dysphagia, stricture, and aspiration pneumonia, and derive treatment- and site-specific estimates. Results: Prevalence of dysphagia, stricture, pneumonia, and aspiration pneumonia was 45.3% (95% confidence interval [CI]: 44.5-46.1), 10.2% (95% CI: 9.7-10.7), 26.3% (95% CI: 25.6-26.9), and 8.6% (95% CI: 8.2-9.1), respectively. Dysphagia increased by 11.7% over the 10-year period (P <.001). Prevalence was highest after chemoradiation and multimodality therapy. Conclusion: Comparing to published rates using similar methodology the preceding decade (1992-1999), prevalence of dysphagia based on claims data was similar in 2002-2011 in this study. These results suggest persistence of dysphagia as a highly prevalent morbidity, even in the decade in which highly conformal radiotherapy and minimally invasive surgeries were popularized.",
keywords = "SEER-Medicare, aspiration pneumonia, dysphagia, head and neck cancer, stricture",
author = "Hutcheson, {Katherine A.} and Zhannat Nurgalieva and Hui Zhao and Gunn, {Gary B.} and Giordano, {Sharon H.} and Bhayani, {Mihir K.} and Lewin, {Jan S.} and Lewis, {Carol M.}",
note = "Funding Information: This work was supported by the MD Anderson Institutional Research Grant fund and the Duncan Family Institute. Dr. Hutcheson receives funding support from the National Cancer Institute (R03CA188162; R01CA218148) and the National Institutes of Health (NIH)/National Institute for Dental and Craniofacial Research (1R01DE025248). The authors also acknowledge infrastructure support from NCI Cancer Center Support Grant (P30CA016672). The authors gratefully acknowledge administrative support of Ms. Janet Hampton. Funding Information: National Cancer Institute, Grant/Award Numbers: R01CA218148R03CA188162, R01CA218148, R03CA188162; NCI Cancer Center Support Grant, Grant/Award Number: P30CA016672; University of Texas MD Anderson Cancer Center, Grant/ Award Number: Toward Preventing Pneumonia in Chronic Aspirators Videofluoroscopic Grading of Dysphagia in Organ Pr; NCI Cancer Center Support, Grant/Award Number: P30CA016672; National Institutes of Health (NIH)/National Institute for Dental and Craniofacial Research, Grant/Award Number: 1R01DE025248; MD Anderson Institutional Research Publisher Copyright: {\textcopyright} 2018 Wiley Periodicals, Inc.",
year = "2019",
month = feb,
doi = "10.1002/hed.25412",
language = "English (US)",
volume = "41",
pages = "479--487",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "Wiley-Liss Inc.",
number = "2",
}