TY - GEN
T1 - Ultra low dose CT for attenuation correction in PET/CT
AU - Colsher, James G.
AU - Hsieh, Jiang
AU - Thibault, Jean Baptiste
AU - Lonn, Albert
AU - Pan, Tinsu
AU - Lokitz, Stephen J.
AU - Turkington, Timothy G.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2008
Y1 - 2008
N2 - In this paper, we present an ultra low-dose CT acquisition and reconstruction technique that provides sufficient image quality for PET attenuation correction while keeping the CT dose to a minimum. With PET/CT, CT is used instead of radioactive transmission sources to acquire data for attenuation correction. While this results in higher radiation dose to the patient, the CT images are also viewed with the PET images and provide an anatomical reference to aid the physician in localizing tumors. We found that using low tube voltage and current results in severe shading and CT number shifts and causes artifacts and quantitative errors in PET images. By adding a simple low pass filter to CT reconstruction prior to the logarithmic step, shading and CT number shifts are reduced substantially. The resulting CT number accuracy and uniformity of the images with the proposed approach makes them acceptable for PET attenuation correction.
AB - In this paper, we present an ultra low-dose CT acquisition and reconstruction technique that provides sufficient image quality for PET attenuation correction while keeping the CT dose to a minimum. With PET/CT, CT is used instead of radioactive transmission sources to acquire data for attenuation correction. While this results in higher radiation dose to the patient, the CT images are also viewed with the PET images and provide an anatomical reference to aid the physician in localizing tumors. We found that using low tube voltage and current results in severe shading and CT number shifts and causes artifacts and quantitative errors in PET images. By adding a simple low pass filter to CT reconstruction prior to the logarithmic step, shading and CT number shifts are reduced substantially. The resulting CT number accuracy and uniformity of the images with the proposed approach makes them acceptable for PET attenuation correction.
UR - http://www.scopus.com/inward/record.url?scp=67649183861&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67649183861&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2008.4774499
DO - 10.1109/NSSMIC.2008.4774499
M3 - Conference contribution
AN - SCOPUS:67649183861
SN - 9781424427154
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 5506
EP - 5511
BT - 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
T2 - 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Y2 - 19 October 2008 through 25 October 2008
ER -