Uncommon Cancers of the Bladder

Arlene O. Siefker-Radtke; Bogdan A. Czerniak; Colin P. Dinney; Randall E. Millikan

doi:10.1002/0470030542.ch2

Uncommon Cancers of the Bladder

Arlene O. Siefker-Radtke, Bogdan A. Czerniak, Colin P. Dinney, Randall E. Millikan

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

Micropapillary, sarcomatoid, and small cell carcinomas are uncommon, aggressive variants usually encountered in the evolution of high-grade nonpapillary transitional cell carcinoma (TCC). Of these, only small cell carcinoma is effectively treated with currently available systemic therapy. Adenocarcinoma and squamous cancers can also arise from the urothelium. Neither is as sensitive to chemotherapy as conventional TCC, but a subset (currently indefinable save in retrospect) does well. Dominant lymphoepithelioma has a favorable prognosis. Urachal cancers require preoperative recognition for optimal surgical management, and are being shown to be somewhat responsive to regimens useful in colon cancer. Mesenchymal tumors are exceedingly rare and are treated like other pelvic sarcomas.

Original language	English (US)
Title of host publication	Textbook of Uncommon Cancer, Third Edition
Publisher	John Wiley & Sons, Ltd
Pages	18-26
Number of pages	9
ISBN (Print)	0470012021, 9780470012024
DOIs	https://doi.org/10.1002/0470030542.ch2
State	Published - Jul 11 2006

Keywords

Lymphoepithelioma
Micropapillary
Sarcomatoid
Small cell
Urachal
Urothelium

ASJC Scopus subject areas

General Medicine

Access to Document

10.1002/0470030542.ch2

Cite this

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abstract = "Micropapillary, sarcomatoid, and small cell carcinomas are uncommon, aggressive variants usually encountered in the evolution of high-grade nonpapillary transitional cell carcinoma (TCC). Of these, only small cell carcinoma is effectively treated with currently available systemic therapy. Adenocarcinoma and squamous cancers can also arise from the urothelium. Neither is as sensitive to chemotherapy as conventional TCC, but a subset (currently indefinable save in retrospect) does well. Dominant lymphoepithelioma has a favorable prognosis. Urachal cancers require preoperative recognition for optimal surgical management, and are being shown to be somewhat responsive to regimens useful in colon cancer. Mesenchymal tumors are exceedingly rare and are treated like other pelvic sarcomas.",

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AU - Czerniak, Bogdan A.

AU - Dinney, Colin P.

AU - Millikan, Randall E.

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Uncommon Cancers of the Bladder

Abstract

Keywords

ASJC Scopus subject areas

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