@article{8290319d455049d8849390072a923c5f,
title = "Understanding the pain experience in hip and knee osteoarthritis - an OARSI/OMERACT initiative",
abstract = "Objective: To examine the pain experience of people with hip or knee osteoarthritis (OA), particularly changes over time and most distressing features. Method: Focus groups in individuals aged 40+ years with painful hip or knee OA obtained detailed descriptions of OA pain from early to late disease. A modified Patient Generated Index (PGI) was used to assess the features of OA pain that participants found most distressing. Content analysis was performed to examine response patterns; descriptive statistics were used to summarize PGI responses. Results: Mean age of the 143 participants (52 hip OA; 91 knee OA) was 69.5 years (47-92 years); 60.8% were female and 93.7% Caucasian. Participants described two distinct types of pain - a dull, aching pain, which became more constant over time, punctuated increasingly with short episodes of a more intense, often unpredictable, emotionally draining pain. The latter, but not the former, resulted in significant avoidance of social and recreational activities. From PGI responses, distressing pain features were: the pain itself (particularly intense and unpredictable pain) and the pain's impact on mobility, mood and sleep. Conclusions: Two distinct pain types were identified. Intermittent intense pain, particularly when unpredictable, had the greatest impact on quality of life.",
keywords = "Hip, Knee, Osteoarthritis, Pain, Qualitative studies",
author = "Hawker, {G. A.} and L. Stewart and French, {M. R.} and J. Cibere and Jordan, {J. M.} and L. March and M. Suarez-Almazor and R. Gooberman-Hill",
note = "Funding Information: We would also like to acknowledge the following members of the OMERACT 7 Total Articular Replacement Special Interest Group: Maxime Dougados, Jean-Francis Maillefert, Laure Gossec, Roy D Altman, Karsten Dreinhoefer, Klaus-Peter Geunther, Karel Pavelka, Marc C Hochberg, Jeffery N Katz, L Stephan Lomander, Nizar Mahomed, Ewa M Roos, Thasia G Woodworth and Gustavo Zanoli. In addition, we would like to acknowledge OMERACT and OARSI for their support for this research through facilitation of meetings of the project team and partial unrestricted funding of the work, and unrestricted support from Pfizer, Novartis, Astra Zeneca, Pharmasciences, Rottapharm and Negma. Funding Information: We are grateful to the 143 people with OA who took part in the study. The authors would like to thank the various site research teams that made this work possible: Bristol, UK : Paul Dieppe, Gillian Woolhead, Fiona MacKichan, Susan Williams, Catharine Elliott, Simone Angel; Houston, USA : Carol Looney, MS and National Institute for Arthritis, Musculoskeletal and Skin Disorders (NIAMS) grant R01 AR49999; North Carolina, USA : Carol Patterson, Janice Woodard, Sue Savage-Guin, Lynn Joyner, Erik Myers, Linda Miles, Britta Schoster, Leigh Callahan; Sydney, Australia : Annica Barcenilla, Sowmyar Gandham, Marita Cross and Arthritis Australia for a Grant-in-Aid to coordinate the Sydney groups; Toronto, Canada : Aileen Davis, Monique Gignac, Joanna Sale, Sheena Sharma, Lucy Frankel, Aodhan Wall, Pilar Furio-Hong, Angela Wall, Ming-Ai Lam, Debbie Sutton, Denise van Amsterdam, Shalini Misir, Jennifer Boyle; Vancouver, Canada : Paul Adams. Funding Information: Dr. Cibere received a speaker honorarium from Amgen and research funding from Centocor Research and Development, Inc. Dr. Suarez-Almazor holds a K24 career award from NIAMS, and is the Director of the Houston Center for Education and Research in Therapeutics, funded by the Agency for Health Research and Quality. The other authors have no conflict of interest to report.",
year = "2008",
month = apr,
doi = "10.1016/j.joca.2007.12.017",
language = "English (US)",
volume = "16",
pages = "415--422",
journal = "Osteoarthritis and Cartilage",
issn = "1063-4584",
publisher = "W.B. Saunders Ltd",
number = "4",
}