Uveitis associated with varicella virus vaccine

Bita Esmaeli-Gutstein; Jan Z. Winkelman

doi:10.1016/S0002-9394(99)00059-8

Uveitis associated with varicella virus vaccine

Bita Esmaeli-Gutstein, Jan Z. Winkelman

Plastic Surgery

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45 Scopus citations

Abstract

PURPOSE: To report a case of uveitis associated with the live attenuated varicella virus vaccine (Varivax; Merck and Co, Inc, West Point, Pennsylvania) in a young, otherwise healthy girl. METHODS: The time of onset of uveitis in relation to vaccination and the number and the pattern of distribution of vesicles were noted. The patient received oral acyclovir and topical steroids and cycloplegic drops. RESULTS: The uveitis and vesicular rash improved significantly after 7 days of treatment. A literature review and communications with the drug's manufacturer disclosed no identifiable previous cases of uveitis associated with Varivax. CONCLUSIONS: Uveitis should be recognized as a possible adverse side effect of the varicella vaccine.

Original language	English (US)
Pages (from-to)	733-734
Number of pages	2
Journal	American Journal of Ophthalmology
Volume	127
Issue number	6
DOIs	https://doi.org/10.1016/S0002-9394(99)00059-8
State	Published - Jun 1999

ASJC Scopus subject areas

Ophthalmology

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10.1016/S0002-9394(99)00059-8

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abstract = "PURPOSE: To report a case of uveitis associated with the live attenuated varicella virus vaccine (Varivax; Merck and Co, Inc, West Point, Pennsylvania) in a young, otherwise healthy girl. METHODS: The time of onset of uveitis in relation to vaccination and the number and the pattern of distribution of vesicles were noted. The patient received oral acyclovir and topical steroids and cycloplegic drops. RESULTS: The uveitis and vesicular rash improved significantly after 7 days of treatment. A literature review and communications with the drug's manufacturer disclosed no identifiable previous cases of uveitis associated with Varivax. CONCLUSIONS: Uveitis should be recognized as a possible adverse side effect of the varicella vaccine.",

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AU - Winkelman, Jan Z.

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AB - PURPOSE: To report a case of uveitis associated with the live attenuated varicella virus vaccine (Varivax; Merck and Co, Inc, West Point, Pennsylvania) in a young, otherwise healthy girl. METHODS: The time of onset of uveitis in relation to vaccination and the number and the pattern of distribution of vesicles were noted. The patient received oral acyclovir and topical steroids and cycloplegic drops. RESULTS: The uveitis and vesicular rash improved significantly after 7 days of treatment. A literature review and communications with the drug's manufacturer disclosed no identifiable previous cases of uveitis associated with Varivax. CONCLUSIONS: Uveitis should be recognized as a possible adverse side effect of the varicella vaccine.

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Uveitis associated with varicella virus vaccine

Abstract

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