TY - JOUR
T1 - Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse
AU - Giles, Francis
AU - Verstovsek, Srdan
AU - Garcia-Manero, Guillermo
AU - Thomas, Deborah
AU - Ravandi, Farhad
AU - Wierda, William
AU - Ferrajoli, Alessandra
AU - Kornblau, Steve
AU - Jabbour, Elias
AU - Shan, Jianqin
AU - O'Brien, Susan
AU - Albitar, Maher
AU - Kantarjian, Hagop
PY - 2006/7
Y1 - 2006/7
N2 - In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13%) [Overall survival (OS), 64% at 1 year, 22% at 5 years]; intermediate, 137 patients (23%) (OS, 38% at 1 year, 12% at 5 years); and poor, 386 patients (64%) (OS, 17% at 1 year 6% at 5 years). The EPI is reproducible and useful.
AB - In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13%) [Overall survival (OS), 64% at 1 year, 22% at 5 years]; intermediate, 137 patients (23%) (OS, 38% at 1 year, 12% at 5 years); and poor, 386 patients (64%) (OS, 17% at 1 year 6% at 5 years). The EPI is reproducible and useful.
KW - Acute myeloid leukaemia
KW - First relapse
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=33744803234&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33744803234&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2141.2006.06106.x
DO - 10.1111/j.1365-2141.2006.06106.x
M3 - Article
C2 - 16803568
AN - SCOPUS:33744803234
SN - 0007-1048
VL - 134
SP - 58
EP - 60
JO - British Journal of Haematology
JF - British Journal of Haematology
IS - 1
ER -