TY - JOUR
T1 - Validity of Endoscopic Ultrasound Findings of Chronic Pancreatitis
T2 - Evaluation from the Viewpoint of Disease Risk Factors
AU - Yamabe, Akane
AU - Irisawa, Atsushi
AU - Bhutani, Manoop S.
AU - Sato, Ai
AU - Maki, Takumi
AU - Takasaki, Yusuke
AU - Yoshida, Yoshitsugu
AU - Yamamoto, Shogo
AU - Shibukawa, Goro
N1 - Publisher Copyright:
© 2021 S. Karger AG. All rights reserved.
PY - 2021/2
Y1 - 2021/2
N2 - Background: The diagnosis of chronic pancreatitis (CP) using endoscopic ultrasound (EUS) criteria, referred to as the Rosemont classification (RC), has been widely performed. However, the validity of the RC, which was based on expert opinion, is still controversial. If EUS findings are associated with CP, then they should be associated with risk factors for CP. In this study, to verify the appropriateness of the RC and each EUS finding, we performed a retrospective analysis from the viewpoint of risk factors for CP. Summary: Three hundred and forty-four patients were enrolled in this study. Clinical background characteristics that associate with CP were alcohol intake, smoking, history of acute pancreatitis (AP), and age. The correlation between EUS criteria for CP and clinical background was investigated. All EUS findings except the presence of cysts showed significant correlations with one or 2 of the 3 following factors: ethanol (EtOH) intake, smoking status, and history of AP. Results of the univariate and multivariate analyses showed that 3 factors (EtOH intake, smoking, and history of AP) other than age were positively correlated with the RC. Moreover, the risk of progression from normal to consistent CP to indeterminate and suggestive CP was found to increase with increasing EtOH intake. Key Messages: The RC and each EUS finding was validated from the viewpoint of risk factors for CP.
AB - Background: The diagnosis of chronic pancreatitis (CP) using endoscopic ultrasound (EUS) criteria, referred to as the Rosemont classification (RC), has been widely performed. However, the validity of the RC, which was based on expert opinion, is still controversial. If EUS findings are associated with CP, then they should be associated with risk factors for CP. In this study, to verify the appropriateness of the RC and each EUS finding, we performed a retrospective analysis from the viewpoint of risk factors for CP. Summary: Three hundred and forty-four patients were enrolled in this study. Clinical background characteristics that associate with CP were alcohol intake, smoking, history of acute pancreatitis (AP), and age. The correlation between EUS criteria for CP and clinical background was investigated. All EUS findings except the presence of cysts showed significant correlations with one or 2 of the 3 following factors: ethanol (EtOH) intake, smoking status, and history of AP. Results of the univariate and multivariate analyses showed that 3 factors (EtOH intake, smoking, and history of AP) other than age were positively correlated with the RC. Moreover, the risk of progression from normal to consistent CP to indeterminate and suggestive CP was found to increase with increasing EtOH intake. Key Messages: The RC and each EUS finding was validated from the viewpoint of risk factors for CP.
KW - Chronic pancreatitis
KW - Endoscopic ultrasound
KW - Risk factor
KW - Rosemont classification
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U2 - 10.1159/000504780
DO - 10.1159/000504780
M3 - Article
C2 - 31801132
AN - SCOPUS:85076580898
SN - 0012-2823
VL - 102
SP - 289
EP - 297
JO - Digestion
JF - Digestion
IS - 2
ER -