Abstract
Cytologic evidence of herpes viral infection within cells from body cavity effusions is extremely uncommon. The authors report the case of a 57-year-old woman who was treated with chemotherapy and irradiation for malignant lymphoma and subsequently developed disseminated varicella-zoster infection with pleural involvement. Cytologic examination of pleural fluid revealed cytopathic changes caused by the varicella-zoster virus, which were confirmed by electron microscopy and viral culture of the effusion. The cytologic and ultrastructural features of the virus-infected cells are described, and the pathogenesis of the effusion and sequence of events in varicella-zoster virus-cell interaction are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 522-526 |
| Number of pages | 5 |
| Journal | American journal of clinical pathology |
| Volume | 85 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1986 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine