TY - JOUR
T1 - Venous thrombosis associated with peripherally inserted central catheters
T2 - A retrospective analysis of the Cleveland clinic experience
AU - Chemaly, Roy F.
AU - De Parres, Joaquin Barbara
AU - Rehm, Susan J.
AU - Adal, Karim A.
AU - Lisgaris, Michelle V.
AU - Katz-Scott, Debbie S.
AU - Curtas, Susan
AU - Gordon, Steven M.
AU - Steiger, Ezra
AU - Olin, Jeffrey
AU - Longworth, David L.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2002/5/1
Y1 - 2002/5/1
N2 - Peripherally inserted central catheters (PICCs) have become popular for long courses of intravenously administration of antibiotics. Although these devices are generally regarded as safe, thrombotic complications have been associated with their use. In a retrospective review, 51 (2.47%) of 2063 patients who had a PICC placed during 1994-1996 were found to have developed a total of 52 PICC-associated venous thromboses (VTs). Two patients received the diagnosis of pulmonary embolism that was a complication of VT. Risk factors for VT identified by multiple logistic regression analysis were younger age, history of VT, discharge to a skilled-nursing facility, and therapy with amphotericin B. VT is a significant complication of PICC placement. It may occur more frequently than previously recognized and may be complicated by pulmonary embolism. Clinicians should maintain a high index of suspicion, especially for high-risk patients.
AB - Peripherally inserted central catheters (PICCs) have become popular for long courses of intravenously administration of antibiotics. Although these devices are generally regarded as safe, thrombotic complications have been associated with their use. In a retrospective review, 51 (2.47%) of 2063 patients who had a PICC placed during 1994-1996 were found to have developed a total of 52 PICC-associated venous thromboses (VTs). Two patients received the diagnosis of pulmonary embolism that was a complication of VT. Risk factors for VT identified by multiple logistic regression analysis were younger age, history of VT, discharge to a skilled-nursing facility, and therapy with amphotericin B. VT is a significant complication of PICC placement. It may occur more frequently than previously recognized and may be complicated by pulmonary embolism. Clinicians should maintain a high index of suspicion, especially for high-risk patients.
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U2 - 10.1086/339808
DO - 10.1086/339808
M3 - Article
C2 - 11941543
AN - SCOPUS:0036570247
SN - 1058-4838
VL - 34
SP - 1179
EP - 1183
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 9
ER -