@inbook{513c5579b13748c084bd9f05fbda5587,
title = "Visualizing intermolecular interactions in T cells",
abstract = "The use of appropriate fluorescent proteins has allowed the use of FRET microscopy for investigation of intermolecular interactions in living cells. This method has the advantage of both being dynamic and of working at the subcellular level, so that the time and place where proteins interact can be visualized. We have used FRET microscopy to analyze the interactions between the T cell antigen receptor and the coreceptors CD4 and CD8. This chapter reviews data on how these coreceptors are recruited to the immunological synapse, and how they interact when the T cell is stimulated by different ligands.",
author = "Gascoigne, {Nicholas R.J.} and Jeanette Ampudia and Clamme, {Jean Pierre} and Guo Fu and Carina Lotz and Michel Mallaun and Nathalie Niederberger and Ed Palmer and Vasily Rybakin and Yachi, {Pia P.} and Tomasz Zal",
note = "Funding Information: Work from this lab was funded by the NIH (R01GM065230 and AI074074 to N.R.J.G., T32HL07195 to P.P.Y., T32AI07290 and K22AI065688 to T.Z.). C.L. was supported by Deutsche Krebshilfe. J-P.C. was supported by a Cancer Research Institute Postdoctoral Fellowship. This is TSRI manuscript number 19758.",
year = "2009",
doi = "10.1007/978-3-540-93864-4_2",
language = "English (US)",
isbn = "9783540938620",
series = "Current Topics in Microbiology and Immunology",
publisher = "Springer Verlag",
number = "1",
pages = "31--46",
booktitle = "Visualizing Immunity",
edition = "1",
}