What is the best adjuvant treatment for very young patients with medulloblastoma?

James W. Clarke; Mersiha Hadziahmetovic; Katherine Tzou; Ching C. Lau; Arnold C. Paulino; John C. Grecula; Joseph F. Montebello; Nina A. Mayr; Simon S. Lo

doi:10.1586/14737175.7.4.373

What is the best adjuvant treatment for very young patients with medulloblastoma?

James W. Clarke, Mersiha Hadziahmetovic, Katherine Tzou, Ching C. Lau, Arnold C. Paulino, John C. Grecula, Joseph F. Montebello, Nina A. Mayr, Simon S. Lo

Radiation Oncology

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

The standard treatment for medulloblastoma is surgery followed by adjuvant chemotherapy and external beam radiotherapy to the craniospinal axis and posterior fossa. However, in very young children, craniospinal irradiation has a more significant detrimental effect in terms of neurocognitive function and growth. This article reviews the different strategies used for very young patients with medulloblastoma.

Original language	English (US)
Pages (from-to)	373-381
Number of pages	9
Journal	Expert review of neurotherapeutics
Volume	7
Issue number	4
DOIs	https://doi.org/10.1586/14737175.7.4.373
State	Published - Apr 2007

Keywords

Adjuvant
Medulloblastoma
Young children

ASJC Scopus subject areas

General Neuroscience
Clinical Neurology
Pharmacology (medical)

Access to Document

10.1586/14737175.7.4.373

Cite this

@article{8fe788675afb45648f88b9539ce4c988,

title = "What is the best adjuvant treatment for very young patients with medulloblastoma?",

abstract = "The standard treatment for medulloblastoma is surgery followed by adjuvant chemotherapy and external beam radiotherapy to the craniospinal axis and posterior fossa. However, in very young children, craniospinal irradiation has a more significant detrimental effect in terms of neurocognitive function and growth. This article reviews the different strategies used for very young patients with medulloblastoma.",

keywords = "Adjuvant, Medulloblastoma, Young children",

author = "Clarke, {James W.} and Mersiha Hadziahmetovic and Katherine Tzou and Lau, {Ching C.} and Paulino, {Arnold C.} and Grecula, {John C.} and Montebello, {Joseph F.} and Mayr, {Nina A.} and Lo, {Simon S.}",

year = "2007",

month = apr,

doi = "10.1586/14737175.7.4.373",

language = "English (US)",

volume = "7",

pages = "373--381",

journal = "Expert review of neurotherapeutics",

issn = "1473-7175",