What T cells see in WT-1

Jeffrey J. Molldrem

doi:10.1182/blood-2012-06-433979

What T cells see in WT-1

Jeffrey J. Molldrem

Stem Cell Transplantation

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

The Wilms tumor protein, WT-1, is a widely recognized tumor antigen that is aberrantly expressed in myeloid and lymphoid leukemia and in this issue of Blood, Doubrovina et al report the most extensive catalog heretofore of HLA-restricted immunogenic peptides derived from WT-1, which are recognized by CD8 and CD4T cells.

Original language	English (US)
Pages (from-to)	1540-1541
Number of pages	2
Journal	Blood
Volume	120
Issue number	8
DOIs	https://doi.org/10.1182/blood-2012-06-433979
State	Published - Aug 23 2012

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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abstract = "The Wilms tumor protein, WT-1, is a widely recognized tumor antigen that is aberrantly expressed in myeloid and lymphoid leukemia and in this issue of Blood, Doubrovina et al report the most extensive catalog heretofore of HLA-restricted immunogenic peptides derived from WT-1, which are recognized by CD8 and CD4T cells.",

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AB - The Wilms tumor protein, WT-1, is a widely recognized tumor antigen that is aberrantly expressed in myeloid and lymphoid leukemia and in this issue of Blood, Doubrovina et al report the most extensive catalog heretofore of HLA-restricted immunogenic peptides derived from WT-1, which are recognized by CD8 and CD4T cells.

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What T cells see in WT-1

Abstract

ASJC Scopus subject areas

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