Współczesny stan badań nad koniugatami i innymi systemami dostarczania leków w leczeniu schorzeń nowotworowych i innych jednostek chorobowych.

Translated title of the contribution: Current status of research on conjugates and related drug delivery systems in the treatment of cancer and other diseases

Dmitry Nevozhay, Urszula Kańska, Renata Budzyńska, Janusz Boratyński

Research output: Contribution to journalReview articlepeer-review

87 Scopus citations

Abstract

Drug delivery systems is an umbrella term describing different types of carrier-drug and carrier-protein conjugates, liposomes, polyplexes, micelles, and hybrid types. Such systems were designed with the aim to enhance delivery and to improve the selectivity and pharmacological properties of both conventional drugs and newly developed agents. In this review the current state-of-the-art in the design of drug delivery systems is described, with particular emphasis on agents developed to deliver antitumor agents. The advantages, limitations, and disadvantages of the particular types of drug delivery systems as well as the theoretical and practical basis of their action are also highlighted here. In addition, results of preclinical and clinical studies on the most developed examples of drug delivery systems to date are summarized.

Translated title of the contributionCurrent status of research on conjugates and related drug delivery systems in the treatment of cancer and other diseases
Original languagePolish
Pages (from-to)350-360
Number of pages11
JournalPostepy higieny i medycyny doświadczalnej (Online)
Volume61
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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