X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology

Medicine & Life Sciences

• Double-Stranded DNA Breaks 87%
• Cell Biology 66%
• X-Rays 59%
• DNA-Activated Protein Kinase 44%
• Cryoelectron Microscopy 41%
• Catalytic Domain 27%
• Neoplasms 24%
• immune RNA 23%
• X Ray Crystallography 20%
• Factor X 20%
• RNA Viruses 17%
• DNA 17%
• Licensure 16%
• T-Cell Antigen Receptor 15%
• Innate Immunity 14%
• Biochemistry 13%
• Ligation 13%
• DNA Damage 13%
• Poisons 11%
• Phosphorylation 10%
• Antibodies 8%

Chemistry

• Cryo-Electron Microscopy 100%
• X-Ray Scattering 86%
• Small Angle X-Ray Scattering 74%
• X-Ray 45%
• Heterodimer 43%
• Statistical Ensemble 37%
• Biochemistry 34%
• Disorder 32%
• Protein 31%
• Toxic 28%