Yttrium-90 Radioembolization for Metastatic Colorectal Cancer

Steven Y Huang; Ching-Wei David Tzeng; Armeen Mahvash

doi:10.1007/978-3-031-09323-4_43

Yttrium-90 Radioembolization for Metastatic Colorectal Cancer

Steven Y Huang, Ching-Wei David Tzeng, Armeen Mahvash

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The role of Yttrium-90 radioembolization for patients with metastatic colorectal carcinoma to the liver is evolving. This chapter reviews the principles of Yttrium-90 radioembolization, dosimetry calculations and considerations, treatment assessment, and published data with specific attention to studies in which Yttrium-90 was used as adjunctive or refractory treatment to first-line chemotherapy. A special emphasis is placed on the potential utility of Yttrium-90 in the surgical patient, specifically, highlighting the role of Yttrium-90 for (1) simultaneous induction of ipsilateral tumour control with concurrent contralateral future liver remnant hypertrophy and (2) downstaging patients to resection.

Original language	English (US)
Title of host publication	Colorectal Liver Metastasis
Publisher	Springer International Publishing
Pages	397-406
Number of pages	10
ISBN (Electronic)	9783031093234
ISBN (Print)	9783031093227
DOIs	https://doi.org/10.1007/978-3-031-09323-4_43
State	Published - Jan 1 2022

Keywords

Colorectal liver metastasis
Radioembolization
Yttrium-90

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-031-09323-4_43

Cite this

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title = "Yttrium-90 Radioembolization for Metastatic Colorectal Cancer",

abstract = "The role of Yttrium-90 radioembolization for patients with metastatic colorectal carcinoma to the liver is evolving. This chapter reviews the principles of Yttrium-90 radioembolization, dosimetry calculations and considerations, treatment assessment, and published data with specific attention to studies in which Yttrium-90 was used as adjunctive or refractory treatment to first-line chemotherapy. A special emphasis is placed on the potential utility of Yttrium-90 in the surgical patient, specifically, highlighting the role of Yttrium-90 for (1) simultaneous induction of ipsilateral tumour control with concurrent contralateral future liver remnant hypertrophy and (2) downstaging patients to resection.",

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AU - Tzeng, Ching-Wei David

AU - Mahvash, Armeen

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AB - The role of Yttrium-90 radioembolization for patients with metastatic colorectal carcinoma to the liver is evolving. This chapter reviews the principles of Yttrium-90 radioembolization, dosimetry calculations and considerations, treatment assessment, and published data with specific attention to studies in which Yttrium-90 was used as adjunctive or refractory treatment to first-line chemotherapy. A special emphasis is placed on the potential utility of Yttrium-90 in the surgical patient, specifically, highlighting the role of Yttrium-90 for (1) simultaneous induction of ipsilateral tumour control with concurrent contralateral future liver remnant hypertrophy and (2) downstaging patients to resection.

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Yttrium-90 Radioembolization for Metastatic Colorectal Cancer

Abstract

Keywords

ASJC Scopus subject areas

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