• 6767 Bertner Ave, Mitchell Basic Science Research Building

    77030 Houston

    United States

  • 1145 Citations
  • 15 h-Index
19962019
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Fingerprint Dive into the research topics where Rong Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
B-Cell Chronic Lymphocytic Leukemia Medicine & Life Sciences
alvocidib Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Cations Medicine & Life Sciences
Nucleosides Medicine & Life Sciences

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Research Output 1996 2019

  • 1145 Citations
  • 15 h-Index
  • 21 Article
  • 1 Review article
1 Citation (Scopus)

Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia

Chen, R., Zhu, M., Chaudhari, R. R., Robles, O., Chen, Y., Skillern, W., Qin, Q., Wierda, W. G., Zhang, S., Hull, K. G., Romo, D. & Plunkett Jr, W. K., Jul 1 2019, In : Leukemia. 33, 7, p. 1663-1674 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Survival
Proteins
Blood Proteins
Apoptosis
12 Citations (Scopus)

Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe

Jouanneau, M., McClary, B., Reyes, J. C. P., Chen, R., Chen, Y., Plunkett Jr, W. K., Cheng, X., Milinichik, A. Z., Albone, E. F., Liu, J. O. & Romo, D., Apr 15 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 8, p. 2092-2097 6 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
T-cells
Diazomethane
Derivatives
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
19 Citations (Scopus)

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia

Yeh, Y. Y., Chen, R., Hessler, J., Mahoney, E., Lehman, A. M., Heerema, N. A., Grever, M. R., Plunkett Jr, W. K., Byrd, J. C. & Johnson, A. J., Jan 1 2015, In : Oncotarget. 6, 5, p. 2667-2679 13 p.

Research output: Contribution to journalArticle

alvocidib
Cyclin-Dependent Kinase 9
Cyclin-Dependent Kinases
Leukemia
Up-Regulation
17 Citations (Scopus)

Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer

Koay, E. J., Baio, F. E., Ondari, A., Truty, M. J., Cristini, V., Thomas, R. M., Chen, R., Chatterjee, D., Kang, Y., Zhang, J., Court, L. E., Bhosale, P. R., Tamm, E. P., Qayyum, A., Crane, C. H., Javle, M., Katz, M. H., Gottumukkala, V., Rozner, M. A., Shen, H. & 10 others, Lee, J. E., Wang, H., Chen, Y., Plunkett Jr, W. K., Abbruzzese, J. L., Wolff, R. A., Maitra, A., Ferrari, M., Varadhachary, G. R. & Fleming, J. B., Dec 1 2014, In : Physical Biology. 11, 6, 065002.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Neoplasms
Tomography
DNA
90 Citations (Scopus)

Transport properties of pancreatic cancer describe gemcitabine delivery and response

Koay, E. J., Truty, M. J., Cristini, V., Thomas, R. M., Chen, R., Chatterjee, D., Kang, Y., Bhosale, P. R., Tamm, E. P., Crane, C., Javle, M., Katz, M. H., Gottumukkala, V., Rozner, M. A., Shen, H., Lee, J. E., Wang, H., Chen, Y., Plunkett Jr, W. K., Abbruzzese, J. L. & 4 others, Wolff, R. A., Varadhachary, G. R., Ferrari, M. & Fleming, J. B., Apr 1 2014, In : Journal of Clinical Investigation. 124, 4, p. 1525-1536 12 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
DNA