Yiling Lu

2014

A comprehensive comparison of normalization methods for loading control and variance stabilization of reverse-phase protein array data

Liu, W., Ju, Z., Lu, Y., Mills, G. B. & Akbani, R., Oct 16 2014, In: Cancer Informatics. 13, p. 109-117 9 p.

Research output: Contribution to journal › Article › peer-review

A Functional Genomic Approach Identifies FAL1 as an Oncogenic Long Noncoding RNA that Associates with BMI1 and Represses p21 Expression in Cancer

Hu, X., Feng, Y., Zhang, D., Zhao, S. D., Hu, Z., Greshock, J., Zhang, Y., Yang, L., Zhong, X., Wang, L. P., Jean, S., Li, C., Huang, Q., Katsaros, D., Montone, K. T., Tanyi, J. L., Lu, Y., Boyd, J., Nathanson, K. L., Li, H., & 2 othersMills, G. B. & Zhang, L., 2014, In: Cancer cell. 26, 3, p. 344-357 14 p.

Research output: Contribution to journal › Article › peer-review

329 Scopus citations

A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: Protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation

Wiegand, K. C., Hennessy, B. T., Leung, S., Wang, Y., Ju, Z., McGahren, M., Kalloger, S. E., Finlayson, S., Stemke-Hale, K., Lu, Y., Zhang, F., Anglesio, M. S., Gilks, B., Mills, G. B., Huntsman, D. G. & Carey, M. S., Feb 22 2014, In: BMC cancer. 14, 1, 120.

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

A pan-cancer proteomic perspective on the cancer genome atlas

Akbani, R., Ng, P. K. S., Werner, H. M. J., Shahmoradgoli, M., Zhang, F., Ju, Z., Liu, W., Yang, J. Y., Yoshihara, K., Li, J., Ling, S., Seviour, E. G., Ram, P. T., Minna, J. D., Diao, L., Tong, P., Heymach, J. V., Hill, S. M., Dondelinger, F., Städler, N., & 9 othersByers, L. A., Meric-Bernstam, F., Weinstein, J. N., Broom, B. M., Verhaak, R. G. W., Liang, H., Mukherjee, S., Lu, Y. & Mills, G. B., May 29 2014, In: Nature communications. 5, 3887.

Research output: Contribution to journal › Article › peer-review

406 Scopus citations

Bayesian sparse graphical models for classification with application to protein expression data

Baladandayuthapani, V., Talluri, R., Ji, Y., Coombes, K. R., Lu, Y., Hennessy, B. T., Davies, M. A. & Mallick, B. K., Sep 1 2014, In: Annals of Applied Statistics. 8, 3, p. 1443-1468 26 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Comprehensive molecular characterization of gastric adenocarcinoma

Cancer Genome Atlas Research Network, Sep 11 2014, In: Nature. 513, 7517, p. 202-209 8 p.

Research output: Contribution to journal › Article › peer-review

4565 Scopus citations

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D., & 290 othersLadanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

Research output: Contribution to journal › Article › peer-review

3986 Scopus citations

Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules

Guo, H., Gao, M., Lu, Y., Liang, J., Lorenzi, P. L., Bai, S., Hawke, D. H., Li, J., Dogruluk, T., Scott, K. L., Jonasch, E., Mills, G. B. & Ding, Z., Jun 26 2014, In: Oncogene. 33, 26, p. 3463-3472 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P., & 11 othersLiu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In: Cancer cell. 26, 6, p. 863-879 17 p.

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer

Lui, V. W., Peyser, N. D., Ng, P. K. S., Hritz, J., Zeng, Y., Lu, Y., Li, H., Wang, L., Gilbert, B. R., General, I. J., Bahar, I., Ju, Z., Wang, Z., Pendleton, K. P., Xiao, X., Du, Y., Vries, J. K., Hammerman, P. S., Garraway, L. A., Mills, G. B., & 2 othersJohnson, D. E. & Grandis, J. R., Jan 21 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1114-1119 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

Agrawal, N., Akbani, R., Aksoy, B. A., Ally, A., Arachchi, H., Asa, S. L., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Behera, M., Bernard, B., Beroukhim, R., Bishop, J. A., Black, A. D., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., & 223 othersBristow, C. A., Brookens, R., Brooks, D., Bryant, R., Buda, E., Butterfield, Y. S. N., Carling, T., Carlsen, R., Carter, S. L., Carty, S. E., Chan, T. A., Chen, A. Y., Cherniack, A. D., Cheung, D., Chin, L., Cho, J., Chu, A., Chuah, E., Cibulskis, K., Ciriello, G., Clarke, A., Clayman, G. L., Cope, L., Copland, J. A., Covington, K., Danilova, L., Davidsen, T., Demchok, J. A., DiCara, D., Dhalla, N., Dhir, R., Dookran, S. S., Dresdner, G., Eldridge, J., Eley, G., El-Naggar, A. K., Eng, S., Fagin, J. A., Fennell, T., Ferris, R. L., Fisher, S., Frazer, S., Frick, J., Gabriel, S. B., Ganly, I., Gao, J., Garraway, L. A., Gastier-Foster, J. M., Getz, G., Gehlenborg, N., Ghossein, R., Gibbs, R. A., Giordano, T. J., Gomez-Hernandez, K., Grimsby, J., Gross, B., Guin, R., Hadjipanayis, A., Harper, H. A., Hayes, D. N., Heiman, D. I., Herman, J. G., Hoadley, K. A., Hofree, M., Holt, R. A., Hoyle, A. P., Huang, F. W., Huang, M., Hutter, C. M., Ideker, T., Iype, L., Jacobsen, A., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kasaian, K., Kebebew, E., Khuri, F. R., Kim, J., Kramer, R., Kreisberg, R., Kucherlapati, R., Kwiatkowski, D. J., Ladanyi, M., Lai, P. H., Laird, P. W., Lander, E., Lawrence, M. S., Lee, D., Lee, E., Lee, S., Lee, W., Leraas, K. M., Lichtenberg, T. M., Lichtenstein, L., Lin, P., Ling, S., Liu, J., Liu, W., Liu, Y., LiVolsi, V. A., Lu, Y., Ma, Y., Mahadeshwar, H. S., Marra, M. A., Mayo, M., McFadden, D. G., Meng, S., Meyerson, M., Mieczkowski, P. A., Miller, M., Mills, G., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Nikiforov, Y. E., Noble, M. S., Ojesina, A. I., Owonikoko, T. K., Ozenberger, B. A., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Paull, E. O., Pedamallu, C. S., Perou, C. M., Prins, J. F., Protopopov, A., Ramalingam, S. S., Ramirez, N. C., Ramirez, R., Raphael, B. J., Rathmell, W. K., Ren, X., Reynolds, S. M., Rheinbay, E., Ringel, M. D., Rivera, M., Roach, J., Robertson, A. G., Rosenberg, M. W., Rosenthal, M., Sadeghi, S., Saksena, G., Sander, C., Santoso, N., Schein, J. E., Schultz, N., Schumacher, S. E., Seethala, R. R., Seidman, J., Senbabaoglu, Y., Seth, S., Sharpe, S., Shaw, K. R. M., Shen, J. P., Shen, R., Sherman, S., Sheth, M., Shi, Y., Shmulevich, I., Sica, G. L., Simons, J. V., Sinha, R., Sipahimalani, P., Smallridge, R. C., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Stewart, C., Stojanov, P., Stuart, J. M., Sumer, S. O., Sun, Y., Tabak, B., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorne, L., Thorsson, V., Tuttle, R. M., Umbricht, C. B., Van Den Berg, D. J., Vandin, F., Veluvolu, U., Verhaak, R. G. W., Vinco, M., Voet, D., Walter, V., Wang, Z., Waring, S., Weinberger, P. M., Weinhold, N., Weinstein, J. N., Weisenberger, D. J., Wheeler, D., Wilkerson, M. D., Wilson, J., Williams, M., Winer, D. A., Wise, L., Wu, J., Xi, L., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zeiger, M. A., Zeng, D., Zenklusen, J. C., Zhao, N., Zhang, H., Zhang, J., Zhang, J., Zhang, W., Zmuda, E. & Zou, L., Oct 23 2014, In: Cell. 159, 3, p. 676-690 15 p.

Research output: Contribution to journal › Article › peer-review

2157 Scopus citations

Local-mass preserving prior distributions for nonparametric bayesian models

Lee, J., MacEachern, S. N., Lu, Y. & Mills, G. B., 2014, In: Bayesian Analysis. 9, 2, p. 307-330 24 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

The Cancer Genome Atlas Research Network, Aug 14 2014, In: Cell. 158, 4, p. 929-944 16 p.

Research output: Contribution to journal › Article › peer-review

1093 Scopus citations

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors

Cheung, L. W. T., Yu, S., Zhang, D., Li, J., Ng, P. K. S., Panupinthu, N., Mitra, S., Ju, Z., Yu, Q., Liang, H., Hawke, D. H., Lu, Y., Broaddus, R. R. & Mills, G. B., Oct 13 2014, In: Cancer cell. 26, 4, p. 479-494 16 p.

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV associated head and neck cancer

Sewell, A., Brown, B., Biktasova, A., Mills, G. B., Lu, Y., Tyson, D. R., Issaeva, N. & Yarbrough, W. G., May 1 2014, In: Clinical Cancer Research. 20, 9, p. 2300-2311 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

76 Scopus citations

Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer

Panupinthu, N., Yu, S., Zhang, D., Zhang, F., Gagea, M., Lu, Y., Grandis, J. R., Dunn, S. E., Lee, H. Y. & Mills, G. B., May 29 2014, In: Oncogene. 33, 22, p. 2846-2856 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Site-specific activation of AKT protects cells from death induced by glucose deprivation

Gao, M., Liang, J., Lu, Y., Guo, H., German, P., Bai, S., Jonasch, E., Yang, X., Mills, G. B. & Ding, Z., Feb 6 2014, In: Oncogene. 33, 6, p. 745-755 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Spatial normalization of reverse phase protein array data

Kaushik, P., Molinelli, E. J., Miller, M. L., Wang, W., Korkut, A., Liu, W., Ju, Z., Lu, Y., Mills, G. & Sander, C., Dec 12 2014, In: PloS one. 9, 12, e97213.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer

Liu, S., Meng, X., Chen, H., Liu, W., Miller, T., Murph, M., Lu, Y., Zhang, F., Gagea, M., Arteaga, C. L., Mills, G. B., Meric-Bernstam, F. & González-Angulo, A. M., 2014, In: Oncotarget. 5, 19, p. 9049-9064 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2013

A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways

Jia, L., Jin, H., Zhou, J., Chen, L., Lu, Y., Ming, Y. & Yu, Y., Feb 15 2013, In: BMC complementary and alternative medicine. 13, 33.

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation

Yao, Y., Suraokar, M., Darnay, B. G., Hollier, B. G., Shaiken, T. E., Asano, T., Chen, C. H., Chang, B. H. J., Lu, Y., Mills, G. B., Sarbassov, D., Mani, S. A., Abbruzzese, J. L. & Reddy, S. A. G., Jan 8 2013, In: Science signaling. 6, 257, ra2.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Comprehensivemolecular characterization of clear cell renal cell carcinoma

Creighton, C. J., Morgan, M., Gunaratne, P. H., Wheeler, D. A., Gibbs, R. A., Robertson, G., Chu, A., Beroukhim, R., Cibulskis, K., Signoretti, S., Vandin, F., Wu, H. T., Raphael, B. J., Verhaak, R. G. W., Tamboli, P., Torres-Garcia, W., Akbani, R., Weinstein, J. N., Reuter, V., Hsieh, J. J., & 268 othersBrannon, A. R., Hakimi, A. A., Jacobsen, A., Ciriello, G., Reva, B., Ricketts, C. J., Linehan, W. M., Stuart, J. M., Rathmell, W. K., Hui, S., Laird, P. W., Muzny, D., Davis, C., Liu, X., Chang, K., Kakkar, N., Treviño, L. R., Benton, S., Reid, J. G., Morton, D., Doddapaneni, H., Yi, H., Lewis, L., Huyen, D., Kovar, C., Zhu, Y., Santibanez, J., Min, W., Hale, W., Kalra, D., Getz, G., Lawrence, M. S., Sougnez, C., Carter, S. L., Sivachenko, A., Lee, L., Stewart, C., Voet, D., Fisher, S., Gabriel, S. B., Lander, E., Schumacher, S. E., Tabak, B., Saksena, G., Onofrio, R. C., Cherniack, A. D., Gentry, J., Ardlie, K., Meyerson, M., Chun, H. J. E., Mungall, A. J., Sipahimalani, P., Stoll, D., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chuah, E., Coope, R. J. N., Dhalla, N., Gorski, S., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lebovitz, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Pleasance, E., Plettner, P., Schein, J. E., Shafiei, A., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Auman, J. T., Tan, D., Jones, C. D., Hoadley, K. A., Mieczkowski, P. A., Mose, L. E., Jefferys, S. R., Topal, M. D., Liquori, C., Turman, Y. J., Yan, S., Waring, S., Buda, E., Walsh, J., Wu, J., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Kucherlapati, R., Park, P., Triche, T., Weisenberger, D. J., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Mahurkar, S., Berman, B. P., Van Den Berg, D. J., Cope, L., Baylin, S. B., Noble, M. S., DiCara, D., Zhang, H., Cho, J., Heiman, D. I., Gehlenborg, N., Mallard, W., Pei, L., Frazer, S., Stojanov, P., Liu, Y., Zhou, L., Kim, J., Chin, L., Benz, C., Yau, C., Reynolds, S. M., Shmulevich, I., Vegesna, R., Kim, H., Wei, Z., Cogdell, D., Jonasch, E., Ding, Z., Lu, Y., Zhang, N., Unruh, A. K., Casasent, T. D., Wakefield, C., Tsavachidou, D., Mills, G. B., Gao, J., Cerami, E., Gross, B., Aksoy, B. A., Sinha, R., Weinhold, N., Sumer, S. O., Taylor, B. S., Shen, R., Ostrovnaya, I., Berger, M. F., Ladanyi, M., Sander, C., Fei, S. S., Stout, A., Spellman, P. T., Rubin, D. L., Liu, T. T., Sam, N., Paull, E. O., Carlin, D., Goldstein, T., Waltman, P., Ellrott, K., Jing, Z., Haussler, D., Xiao, W., Shelton, C., Gardner, J., Penny, R., Sherman, M., Mallery, D., Morris, S., Paulauskis, J., Burnett, K., Shelton, T., Kaelin, W. G., Choueiri, T., Atkins, M. B., Curley, E., Tickoo, S., Thorne, L., Boice, L., Mei, H., Fisher, J. C., Vocke, C. D., Peterson, J., Worrell, R., Merino, M. J., Schmidt, L. S., Czerniak, B. A., Aldape, K. D., Wood, C. G., Boyd, J., Weaver, J. E., Iacocca, M. V., Petrelli, N., Witkin, G., Brown, J., Czerwinski, C., Huelsenbeck-Dill, L., Rabeno, B., Myers, J., Morrison, C., Bergsten, J., Eckman, J., Harr, J., Smith, C., Tucker, K., Zach, L. A., Bshara, W., Gaudioso, C., Dhir, R., Maranchie, J., Nelson, J., Parwani, A., Potapova, C. O., Fedosenko, K., Cheville, J. C., Thompson, R. H., Mosquera, J. M., Rubin, M. A., Blute, M. L., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Davidsen, T., Wang, Z., Yang, L., Tarnuzzer, R. W., Zhang, J., Eley, G., Ferguson, M. L., Mills Shaw, K. R., Guyer, M. S., Ozenberger, B. A. & Sofia, H. J., 2013, In: Nature. 499, 7456, p. 43-49 7 p.

Research output: Contribution to journal › Article › peer-review

2523 Scopus citations

Erratum: Predicting time to ovarian carcinoma recurrence using protein markers (Journal of Clinical Investigation (2013) 123:9 (3740-3750) DOI: 10.1172/JCI68509)

Yang, J. Y., Yoshihara, K., Tanaka, K., Hatae, M., Masuzaki, H., Itamochi, H., Takano, M., Ushijima, K., Tanyi, J. L., Coukos, G., Lu, Y., Mills, G. B. & Verhaak, R., Dec 2 2013, In: Journal of Clinical Investigation. 123, 12, p. 5410 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

3 Scopus citations

Erratum: Network inference using steady-state data and Goldbeter-Koshland kinetics (Bioinformatics (2012) 28: 18 (2342-2348) DOI: 10.1093/bioinformatics/ bts459)

Oates, C. J., Hennessy, B. T., Lu, Y., Mills, G. B. & Mukherjee, S., Mar 2013, In: Bioinformatics. 29, 6, p. 819 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

Lui, V. W. Y., Hedberg, M. L., Li, H., Vangara, B. S., Pendleton, K., Zeng, Y., Lu, Y., Zhang, Q., Du, Y., Gilbert, B. R., Freilino, M., Sauerwein, S., Peyser, N. D., Xiao, D., Diergaarde, B., Wang, L., Chiosea, S., Seethala, R., Johnson, J. T., Kim, S., & 9 othersDuvvuri, U., Ferris, R. L., Romkes, M., Nukui, T., Ng, P. K. S., Garraway, L. A., Hammerman, P. S., Mills, G. B. & Grandis, J. R., Jul 2013, In: Cancer discovery. 3, 7, p. 761-769 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

460 Scopus citations

Integrated genomic characterization of endometrial carcinoma

Getz, G., Gabriel, S. B., Cibulskis, K., Lander, E., Sivachenko, A., Sougnez, C., Lawrence, M., Kandoth, C., Dooling, D., Fulton, R., Fulton, L., Kalicki-Veizer, J., McLellan, M. D., O'Laughlin, M., Schmidt, H., Wilson, R. K., Ye, K., Li, D., Ally, A., Balasundaram, M., & 256 othersBirol, I., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E., Dhalla, N., Guin, R., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Plettner, P., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R. J., Gordon Robertson, A., Cherniack, A. D., Pashtan, I., Saksena, G., Onofrio, R. C., Schumacher, S. E., Tabak, B., Carter, S. L., Hernandez, B., Gentry, J., Salvesen, H. B., Ardlie, K., Winckler, W., Beroukhim, R., Meyerson, M., Hadjipanayis, A., Lee, S., Mahadeshwar, H. S., Park, P., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Xi, R., Yang, L., Dong, Z., Kucherlapati, R., Chin, L., Zhang, J., Todd Auman, J., Balu, S., Bodenheimer, T., Buda, E., Neil Hayes, D., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Parker, J. S., Perou, C. M., Roach, J., Yan, S., Simons, J. V., Soloway, M. G., Tan, D., Topal, M. D., Waring, S., Wu, J., Hoadley, K. A., Baylin, S. B., Bootwalla, M. S., Lai, P. H., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Laird, P. W., Shen, H., Cho, J., Dicara, D., Frazer, S., Heiman, D., Jing, R., Lin, P., Mallard, W., Stojanov, P., Voet, D., Zhang, H., Zou, L., Noble, M., Reynolds, S. M., Shmulevich, I., Arman Aksoy, B., Antipin, Y., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Ladanyi, M., Reva, B., Sander, C., Sinha, R., Onur Sumer, S., Taylor, B. S., Cerami, E., Weinhold, N., Schultz, N., Shen, R., Benz, S., Goldstein, T., Haussler, D., Ng, S., Szeto, C., Stuart, J., Benz, C. C., Yau, C., Zhang, W., Annala, M., Broom, B. M., Casasent, T. D., Ju, Z., Liang, H., Liu, G., Lu, Y., Unruh, A. K., Wakefield, C., Weinstein, J. N., Zhang, N., Liu, Y., Broaddus, R., Akbani, R., Mills, G. B., Adams, C., Barr, T., Black, A. D., Bowen, J., Deardurff, J., Frick, J., Gastier-Foster, J. M., Grossman, T., Harper, H. A., Hart-Kothari, M., Helsel, C., Hobensack, A., Kuck, H., Kneile, K., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Pyatt, R. E., Ramirez, N. C., Tabler, T. R., Vanhoose, N., White, P., Wise, L., Zmuda, E., Barnabas, N., Berry-Green, C., Blanc, V., Boice, L., Button, M., Farkas, A., Green, A., MacKenzie, J., Nicholson, D., Kalloger, S. E., Blake Gilks, C., Karlan, B. Y., Lester, J., Orsulic, S., Borowsky, M., Cadungog, M., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Witkin, G., Nemirovich-Danchenko, E., Potapova, O., Rotin, D., Berchuck, A., Birrer, M., Disaia, P., Monovich, L., Curley, E., Gardner, J., Mallery, D., Penny, R., Dowdy, S. C., Winterhoff, B., Dao, L., Gostout, B., Meuter, A., Teoman, A., Dao, F., Olvera, N., Bogomolniy, F., Garg, K., Soslow, R. A., Abramov, M., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Moiseenko, F., Clarke, B. A., Goodman, M. T., Carney, M. E., Matsuno, R. K., Fisher, J., Huang, M., Kimryn Rathmell, W., Thorne, L., Van Le, L., Dhir, R., Edwards, R., Elishaev, E., Zorn, K., Goodfellow, P. J., Mutch, D., Kahn, A. B., Bell, D. W., Pollock, P. M., Wang, C., Wheeler, D., Shinbrot, E., Gordon Robertson, A., Ding, L., Blake Gilks, C., Mardis, E. R., Ayala, B., Chu, A. L., Jensen, M. A., Kothiyal, P., Pihl, T. D., Pontius, J., Pot, D. A., Snyder, E. E., Srinivasan, D., Mills Shaw, K. R., Sheth, M., Davidsen, T., Eley, G., Ferguson, M. L., Yang, L., Guyer, M. S., Ozenberger, B. A., Sofia, H. J., Gordon Robertson, A. & Levine, D. A., 2013, In: Nature. 497, 7447, p. 67-73 7 p.

Research output: Contribution to journal › Article › peer-review

3629 Scopus citations

Modeling precision treatment of breast cancer

Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R., & 7 othersLu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In: Genome biology. 14, 10, R110.

Research output: Contribution to journal › Article › peer-review

Open Access

208 Scopus citations

Predicting time to ovarian carcinoma recurrence using protein markers

Yang, J. Y., Yoshihara, K., Tanaka, K., Hatae, M., Masuzaki, H., Itamochi, H., Takano, M., Ushijima, K., Tanyi, J. L., Coukos, G., Lu, Y., Mills, G. B. & Verhaak, R. G. W., Sep 3 2013, In: Journal of Clinical Investigation. 123, 9, p. 3740-3750 11 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520

Park, Y. Y., Kim, S. B., Han, H. D., Sohn, B. H., Kim, J. H., Liang, J., Lu, Y., Rodriguez-Aguayo, C., Lopez-Berestein, G., Mills, G. B., Sood, A. K. & Lee, J. S., Jul 2013, In: Hepatology. 58, 1, p. 182-191 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

76 Scopus citations

TCPA: A resource for cancer functional proteomics data

Li, J., Lu, Y., Akbani, R., Ju, Z., Roebuck, P. L., Liu, W., Yang, J. Y., Broom, B. M., Verhaak, R. G. W., Kane, D. W., Wakefield, C., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 2013, In: Nature Methods. 10, 11, p. 1046-1047 2 p.

Research output: Contribution to journal › Letter › peer-review

349 Scopus citations

The cancer genome atlas pan-cancer analysis project

Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., Sander, C., Stuart, J. M., Chang, K., Creighton, C. J., Davis, C., Donehower, L., Drummond, J., Wheeler, D., Ally, A., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chu, A., Chuah, E., & 316 othersChun, H. J. E., Dhalla, N., Guin, R., Hirst, M., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Robertson, A. G., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Varhol, R. J., Beroukhim, R., Bhatt, A. S., Brooks, A. N., Cherniack, A. D., Freeman, S. S., Gabriel, S. B., Helman, E., Jung, J., Meyerson, M., Ojesina, A. I., Pedamallu, C. S., Saksena, G., Schumacher, S. E., Tabak, B., Zack, T., Lander, E. S., Bristow, C. A., Hadjipanayis, A., Haseley, P., Kucherlapati, R., Lee, S., Lee, E., Luquette, L. J., Mahadeshwar, H. S., Pantazi, A., Parfenov, M., Park, P. J., Protopopov, A., Ren, X., Santoso, N., Seidman, J., Seth, S., Song, X., Tang, J., Xi, R., Xu, A. W., Yang, L., Zeng, D., Auman, J. T., Balu, S., Buda, E., Fan, C., Hoadley, K. A., Jones, C. D., Meng, S., Mieczkowski, P. A., Parker, J. S., Perou, C. M., Roach, J., Shi, Y., Silva, G. O., Tan, D., Veluvolu, U., Waring, S., Wilkerson, M. D., Wu, J., Zhao, W., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jeffreys, S. R., Mose, L. E., Simons, J. V., Soloway, M. G., Baylin, S. B., Berman, B. P., Bootwalla, M. S., Danilova, L., Herman, J. G., Hinoue, T., Laird, P. W., Rhie, S. K., Shen, H., Triche, T., Weisenberger, D. J., Carter, S. L., Cibulskis, K., Chin, L., Zhang, J., Sougnez, C., Wang, M., Getz, G., Dinh, H., Doddapaneni, H. V., Gibbs, R., Gunaratne, P., Han, Y., Kalra, D., Kovar, C., Lewis, L., Morgan, M., Morton, D., Muzny, D., Reid, J., Xi, L., Cho, J., Dicara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Kim, J., Lawrence, M. S., Lin, P., Liu, Y., Noble, M. S., Stojanov, P., Voet, D., Zhang, H., Zou, L., Stewart, C., Bernard, B., Bressler, R., Eakin, A., Iype, L., Knijnenburg, T., Kramer, R., Kreisberg, R., Leinonen, K., Lin, J., Liu, Y., Miller, M., Reynolds, S. M., Rovira, H., Shmulevich, I., Thorsson, V., Yang, D., Zhang, W., Amin, S., Wu, C. J., Wu, C. C., Akbani, R., Aldape, K., Baggerly, K. A., Broom, B., Casasent, T. D., Cleland, J., Dodda, D., Edgerton, M., Han, L., Herbrich, S. M., Ju, Z., Kim, H., Lerner, S., Li, J., Liang, H., Liu, W., Lorenzi, P. L., Lu, Y., Melott, J., Nguyen, L., Su, X., Verhaak, R., Wang, W., Wong, A., Yang, Y., Yao, J., Yao, R., Yoshihara, K., Yuan, Y., Yung, A. K., Zhang, N., Zheng, S., Ryan, M., Kane, D. W., Aksoy, B. A., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Kahles, A., Ladanyi, M., Lee, W., Lehmann, K. V., Miller, M. L., Ramirez, R., Rätsch, G., Reva, B., Schultz, N., Senbabaoglu, Y., Shen, R., Sinha, R., Sumer, S. O., Sun, Y., Taylor, B. S., Weinhold, N., Fei, S., Spellman, P., Benz, C., Carlin, D., Cline, M., Craft, B., Goldman, M., Haussler, D., Ma, S., Ng, S., Paull, E., Radenbaugh, A., Salama, S., Sokolov, A., Swatloski, T., Uzunangelov, V., Waltman, P., Yau, C., Zhu, J., Hamilton, S. R., Abbott, S., Abbott, R., Dees, N. D., Delehaunty, K., Ding, L., Dooling, D. J., Eldred, J. M., Fronick, C. C., Fulton, R., Fulton, L. L., Kalicki-Veizer, J., Kanchi, K. L., Kandoth, C., Koboldt, D. C., Larson, D. E., Ley, T. J., Lin, L., Lu, C., Magrini, V. J., Mardis, E. R., McLellan, M. D., McMichael, J. F., Miller, C. A., O'Laughlin, M., Pohl, C., Schmidt, H., Smith, S. M., Walker, J., Wallis, J. W., Wendl, M. C., Wilson, R. K., Wylie, T., Zhang, Q., Burton, R., Jensen, M. A., Kahn, A., Pihl, T., Pot, D., Wan, Y., Levine, D. A., Black, A. D., Bowen, J., Frick, J., Gastier-Foster, J. M., Harper, H. A., Helsel, C., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Ramirez, N. C., Sharpe, S., Wise, L., Zmuda, E., Chanock, S. J., Davidsen, T., Demchok, J. A., Eley, G., Felau, I., Sheth, M., Sofia, H., Staudt, L., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Omberg, L., Margolin, A., Raphael, B. J., Vandin, F., Wu, H. T., Leiserson, M. D. M., Benz, S. C., Vaske, C. J., Noushmehr, H., Wolf, D., Veer, L. V. T., Anastassiou, D., Yang, T. H. O., Lopez-Bigas, N., Gonzalez-Perez, A., Tamborero, D., Xia, Z., Li, W., Cho, D. Y., Przytycka, T., Hamilton, M., McGuire, S., Nelander, S., Johansson, P., Jörnsten, R. & Kling, T., Oct 1 2013, In: Nature Genetics. 45, 10, p. 1113-1120 8 p.

Research output: Contribution to journal › Article › peer-review

5099 Scopus citations

The somatic genomic landscape of glioblastoma

TCGA Research Network, Oct 10 2013, In: Cell. 155, 2, p. 462 1 p.

Research output: Contribution to journal › Article › peer-review

3492 Scopus citations

2012

Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters

He, Y., Zhou, Z., Hofstetter, W. L., Zhou, Y., Hu, W., Guo, C., Wang, L., Guo, W., Pataer, A., Correa, A. M., Lu, Y., Wang, J., Diao, L., Byers, L. A., Wistuba, I. I., Roth, J. A., Swisher, S. G., Heymach, J. V. & Fang, B., 2012, In: PloS one. 7, 2, e31087.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells

Claerhout, S., Dutta, B., Bossuyt, W., Zhang, F., Nguyen-Charles, C., Dennison, J. B., Yu, Q., Yu, S., Balázsi, G., Lu, Y. & Mills, G. B., Jun 26 2012, In: PloS one. 7, 6, e39400.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

An efficient procedure for protein extraction from formalin-fixed, Paraffin-embedded tissues for reverse phase protein arrays

Guo, H., Liu, W., Ju, Z., Tamboli, P., Jonasch, E., Mills, G. B., Lu, Y., Hennessy, B. T. & Tsavachidou, D., Sep 24 2012, In: Proteome Science. 10, 1, 56.

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

A Time-Series DDP for Functional Proteomics Profiles

Nieto-Barajas, L. E., Müller, P., Ji, Y., Lu, Y. & Mills, G. B., Sep 2012, In: Biometrics. 68, 3, p. 859-868 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Hill, S. M., Lu, Y., Molina, J., Heiser, L. M., Spellman, P. T., Speed, T. P., Gray, J. W., Mills, G. B. & Mukherjee, S., Nov 2012, In: Bioinformatics. 28, 21, p. 2804-2810 7 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Comprehensive molecular portraits of human breast tumours

Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., Fulton, L. L., Dooling, D. J., Ding, L., Mardis, E. R., Wilson, R. K., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E., Coope, R. J. N., & 323 othersDhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Pleasance, E., Robertson, A. G., Schein, J. E., Shafiei, A., Sipahimalani, P., Slobodan, J. R., Stoll, D., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zeng, T., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Cherniack, A. D., Saksena, G., Onofrio, R. C., Pho, N. H., Carter, S. L., Schumacher, S. E., Tabak, B., Hernandez, B., Gentry, J., Nguyen, H., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Getz, G., Gabriel, S. B., Meyerson, M., Chin, L., Kucherlapati, R., Hoadley, K. A., Auman, J. T., Fan, C., Turman, Y. J., Shi, Y., Li, L., Topal, M. D., He, X., Chao, H. H., Prat, A., Silva, G. O., Iglesia, M. D., Zhao, W., Usary, J., Berg, J. S., Adams, M., Booker, J., Wu, J., Gulabani, A., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Mose, L. E., Jefferys, S. R., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Malik, S., Mahurkar, S., Shen, H., Weisenberger, D. J., Triche, T., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Berman, B. P., Van Den Berg, D. J., Baylin, S. B., Laird, P. W., Creighton, C. J., Donehower, L. A., Noble, M., Voet, D., Gehlenborg, N., Di Cara, D., Zhang, J., Zhang, H., Wu, C. J., Yingchun Liu, S., Lawrence, M. S., Zou, L., Sivachenko, A., Lin, P., Stojanov, P., Jing, R., Cho, J., Sinha, R., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Park, P. J., Reynolds, S., Kreisberg, R. B., Bernard, B., Bressler, R., Erkkila, T., Lin, J., Thorsson, V., Zhang, W., Shmulevich, I., Ciriello, G., Weinhold, N., Schultz, N., Gao, J., Cerami, E., Gross, B., Jacobsen, A., Sinha, R., Aksoy, B. A., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Anur, P., Spellman, P. T., Lu, Y., Liu, W., Verhaak, R. R. G., Mills, G. B., Akbani, R., Zhang, N., Broom, B. M., Casasent, T. D., Wakefield, C., Unruh, A. K., Baggerly, K., Coombes, K., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zhu, J., Szeto, C. C., Scott, G. K., Yau, C., Paull, E. O., Carlin, D., Wong, C., Sokolov, A., Thusberg, J., Mooney, S., Ng, S., Goldstein, T. C., Ellrott, K., Grifford, M., Wilks, C., Ma, S., Craft, B., Yan, C., Hu, Y., Meerzaman, D., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A. D., Pyatt, R. E., White, P., Zmuda, E. J., Frick, J., Lichtenberg, T. M., Brookens, R., George, M. M., Gerken, M. A., Harper, H. A., Leraas, K. M., Wise, L. J., Tabler, T. R., McAllister, C., Barr, T., Hart-Kothari, M., Tarvin, K., Saller, C., Sandusky, G., Mitchell, C., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Dolzhansky, O., Abramov, M., Voronina, O., Potapova, O., Marks, J. R., Suchorska, W. M., Murawa, D., Kycler, W., Ibbs, M., Korski, K., Spychała, A., Murawa, P., Brzeziński, J. J., Perz, H., Łaźniak, R., Teresiak, M., Tatka, H., Leporowska, E., Bogusz-Czerniewicz, M., Malicki, J., Mackiewicz, A., Wiznerowicz, M., Van Le, X., Kohl, B., Viet Tien, N., Thorp, R., Van Bang, N., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Phuong, T. V. T., Thang, H. Q., Khan, K. Z., Penny, R., Mallery, D., Curley, E., Shelton, C., Yena, P., Ingle, J. N., Couch, F. J., Lingle, W. L., King, T. A., Gonzalez-Angulo, A. M., Dyer, M. D., Liu, S., Meng, X., Patangan, M., Waldman, F., Stöppler, H., Rathmell, W. K., Thorne, L., Huang, M., Boice, L., Hill, A., Morrison, C., Gaudioso, C., Bshara, W., Daily, K., Egea, S. C., Pegram, M. D., Gomez-Fernandez, C., Dhir, R., Bhargava, R., Brufsky, A., Shriver, C. D., Hooke, J. A., Campbell, J. L., Mural, R. J., Hu, H., Somiari, S., Larson, C., Deyarmin, B., Kvecher, L., Kovatich, A. J., Ellis, M. J., Stricker, T., White, K., Olopade, O., Luo, C., Chen, Y., Bose, R., Chang, L. W., Beck, A. H., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Wang, Z., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Shaw, K. R. M., Yang, L., Eley, G., Ferguson, M. L., Tarnuzzer, R. W., Zhang, J., Dillon, L. A. L., Buetow, K., Fielding, P., Ozenberger, B. A., Guyer, M. S., Sofia, H. J. & Palchik, J. D., Oct 4 2012, In: Nature. 490, 7418, p. 61-70 10 p.

Research output: Contribution to journal › Article › peer-review

8965 Scopus citations

EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF

Tarcic, G., Avraham, R., Pines, G., Amit, I., Shay, T., Lu, Y., Zwang, Y., Katz, M., Ben-Chetrit, N., Jacob-Hirsch, J., Virgilio, L., Rechavi, G., Mavrothalassitis, G., Mills, G. B., Domany, E. & Yarden, Y., Apr 2012, In: FASEB Journal. 26, 4, p. 1582-1592 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

80 Scopus citations

Knockdown of RAB25 promotes autophagy and inhibits cell growth in ovarian cancer cells

Liu, Y., Tao, X., Jia, L., Cheng, K. W., Lu, Y., Yu, Y. & Feng, Y., Nov 2012, In: Molecular medicine reports. 6, 5, p. 1006-1012 7 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-raf-ERK1/2-mTOR pathway in breast cancer patients

Duong, M. L. T., Akli, S., Wei, C., Wingate, H. F., Liu, W., Lu, Y., Yi, M., Mills, G. B., Hunt, K. K. & Keyomarsi, K., Mar 2012, In: PLoS genetics. 8, 3, e1002538.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis

Hoshino, D., Jourquin, J., Emmons, S. W., Miller, T., Goldgof, M., Costello, K., Tyson, D. R., Brown, B., Lu, Y., Prasad, N. K., Zhang, B., Mills, G. B., Yarbrough, W. G., Quaranta, V., Seiki, M. & Weaver, A. M., Sep 11 2012, In: Science signaling. 5, 241, ra66.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Scopus citations

Network inference using steady-state data and goldbeter-koshland kinetics

Oates, C. J., Hennessy, B. T., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 2012, In: Bioinformatics. 28, 18, p. 2342-2348 7 p., bts459.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

Park, Y. Y., Kim, K., Kim, S. B., Hennessy, B. T., Kim, S. M., Park, E. S., Lim, J. Y., Li, J., Lu, Y., Gonzalez-Angulo, A. M., Jeong, W., Mills, G. B., Safe, S. & Lee, J. S., Jan 2012, In: EMBO Molecular Medicine. 4, 1, p. 52-67 16 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Sparse Bayesian graphical models for RPPA time course data

Mitra, R., Mueller, P., Ji, Y., Mills, G. & Lu, Y., 2012, Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2012. p. 113-117 5 p. 6507742. (Proceedings - IEEE International Workshop on Genomic Signal Processing and Statistics).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Src inhibition with saracatinib reverses fulvestrant resistance in ER-positive ovarian cancer models in vitro and in vivo

Simpkins, F., Hevia-Paez, P., Sun, J., Ullmer, W., Gilbert, C. A., Da Silva, T., Pedram, A., Levin, E. R., Reis, I. M., Rabinovich, B., Azzam, D., Xu, X. X., Ince, T. A., Yang, J. Y., Verhaak, R. G. W., Lu, Y., Mills, G. B. & Slingerland, J. M., Nov 1 2012, In: Clinical Cancer Research. 18, 21, p. 5911-5923 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Systematic analysis of genotype-specific drug responses in cancer

Kim, N., He, N., Kim, C., Zhang, F., Lu, Y., Yu, Q., Stemke-Hale, K., Greshock, J., Wooster, R., Yoon, S. & Mills, G. B., Nov 15 2012, In: International journal of cancer. 131, 10, p. 2456-2464 9 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Liang, H., Cheung, L. W. T., Li, J., Ju, Z., Yu, S., Stemke-Hale, K., Dogruluk, T., Lu, Y., Liu, X., Gu, C., Guo, W., Scherer, S. E., Carter, H., Westin, S. N., Dyer, M. D., Verhaak, R. G. W., Zhang, F., Karchin, R., Liu, C. G., Lu, K. H., & 4 othersBroaddus, R. R., Scott, K. L., Hennessy, B. T. & Mills, G. B., Nov 2012, In: Genome research. 22, 11, p. 2120-2129 10 p.

Research output: Contribution to journal › Article › peer-review

202 Scopus citations

2011

Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models

Cheong, J. H., Park, E. S., Liang, J., Dennison, J. B., Tsavachidou, D., Nguyen-Charles, C., Cheng, K. W., Hall, H., Zhang, D., Lu, Y., Ravoori, M., Kundra, V., Ajani, J., Lee, J. S., Hong, W. K. & Mills, G. B., Dec 2011, In: Molecular cancer therapeutics. 10, 12, p. 2350-2362 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

210 Scopus citations

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

Cheung, L. W. T., Hennessy, B. T., Li, J., Yu, S., Myers, A. P., Djordjevic, B., Lu, Y., Katherine, S. H., Dyer, M. D., Zhang, F., Ju, Z., Cantley, L. C., Scherer, S. E., Liang, H., Lu, K. H., Broaddus, R. R. & Mills, G. B., Jun 7 2011, In: Cancer discovery. 1, 2, p. 170-185 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

377 Scopus citations

Yiling Lu

Research output

Search results