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2008
The binding stoichiometry of CIN85 SH3 domain A and Cbl-b
Ababou, A., Pfuhl, M. & Ladbury, J. E., Sep 2008, In: Nature Structural and Molecular Biology. 15, 9, p. 890-891 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access4 Scopus citations -
2007
Identification of novel fragment compounds targeted against the pY pocket of v-Src SH2 by computational and NMR screening and thermodynamic evaluation
Taylor, J. D., Gilbert, P. J., Williams, M. A., Pitt, W. R. & Ladbury, J. E., Jun 2007, In: Proteins: Structure, Function and Genetics. 67, 4, p. 981-990 10 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
1984
Increased sister-chromatid exchange in bone-marrow cells of mice exposed to whole cigarette smoke
Benedict, W. F., Banerjee, A., Kangalingam, K. K., Dansie, D. R., Kouri, R. E. & Henry, C. J., Apr 1984, In: Mutation Research/Genetic Toxicology. 136, 1, p. 73-80 8 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
1978
Cyclophosphamide-induced Oncogenic Transformation, Chromosomal Breakage, and Sister Chromatid Exchange following Microsomal Activation
Benedict, W. F., Banerjee, A. & Venkatesan, N., Sep 1978, In: Cancer Research. 38, 9, p. 2922-2924 3 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
2008
Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
Patel, S., George, R., Autore, F., Fraternali, F., Ladbury, J. E. & Nikolova, P. V., 2008, In: Nucleic acids research. 36, 16, p. 5139-5151 13 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
2003
Halophilic adaptation of protein-DNA interactions
Bergqvist, S., Williams, M. A., O'Brien, R. & Ladbury, J. E., Jun 2003, In: Biochemical Society Transactions. 31, 3, p. 677-680 4 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
1979
Production of sister chromatid exchanges by various cancer chemotherapeutic agents
Banerjee, A. & Benedict, W. F., Mar 1 1979, In: Cancer Research. 39, 3, p. 797-799 3 p.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
2008
Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design
Taylor, J. D., Ababou, A., Fawaz, R. R., Hobbs, C. J., Williams, M. A. & Ladbury, J. E., Dec 2008, In: Proteins: Structure, Function and Genetics. 73, 4, p. 929-940 12 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
2001
Site-specific cation binding mediates TATA binding protein - DNA interaction from a hyperthermophilic archaeon
Bergqvist, S., O'Brien, R. & Ladbury, J. E., Feb 27 2001, In: Biochemistry. 40, 8, p. 2419-2425 7 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
2004
The extended interface: Measuring non-local effects in biomolecular interactions
Ladbury, J. E. & Williams, M. A., Oct 2004, In: Current Opinion in Structural Biology. 14, 5, p. 562-569 8 p.Research output: Contribution to journal › Review article › peer-review
64 Scopus citations -
1996
Molecular anchoring of duplex and triplex DNA by disubstituted anthracene-9,10-diones: Calorimetric, UV melting, and competition dialysis studies
Haq, I., Ladbury, J. E., Chowdhry, B. Z. & Jenkins, T. C., Nov 6 1996, In: Journal of the American Chemical Society. 118, 44, p. 10693-10701 9 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
2002
Backbone resonance assignments of the 25kD N-terminal ATPase domain from the Hsp90 chaperone [3]
Salek, R. M., Williams, M. A., Prodromou, C., Pearl, L. H. & Ladbury, J. E., Aug 2002, In: Journal of Biomolecular NMR. 23, 4, p. 327-328 2 p.Research output: Contribution to journal › Letter › peer-review
19 Scopus citations -
Interactions defining the specificity between fungal xylanases and the xylanase-inhibiting protein XIP-I from wheat
Flatman, R., McLauchlan, W. R., Juge, N., Furniss, C., Berrin, J. G., Hughes, R. K., Manzanares, P., Ladbury, J. E., O'Brien, R. & Williamson, G., Aug 1 2002, In: Biochemical Journal. 365, 3, p. 773-781 9 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
1991
Intraocular Tumor Formation of RB Reconstituted Retinoblastoma Cells
Xu, H. J., Sumegi, J., Hu, S. X., Banerjee, A., Uzvolgyi, E., Klein, G. & Benedict, W. F., Aug 15 1991, In: Cancer Research. 51, 16, p. 4481-4485 5 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
1999
Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate
Baraldi, E., Carugo, K. D., Hyvönen, M., Surdo, P. L., Riley, A. M., Potter, B. V. L., O'Brien, R., Ladbury, J. E. & Saraste, M., Apr 15 1999, In: Structure. 7, 4, p. 449-460 12 p.Research output: Contribution to journal › Article › peer-review
170 Scopus citations -
1997
The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin
Tsai, F. T. F., Singh, O. M. P., Skarzynski, T., Wonacott, A. J., Weston, S., Tucker, A., Pauptit, R. A., Breeze, A. L., Poyser, J. P., O'Brien, R., Ladbury, J. E. & Wigley, D. B., 1997, In: Proteins: Structure, Function and Genetics. 28, 1, p. 41-52 12 p.Research output: Contribution to journal › Article › peer-review
169 Scopus citations -
2002
Reversal of halophilicity in a protein-DNA interaction by limited mutation strategy
Bergqvist, S., Williams, M. A., O'Brien, R. & Ladbury, J. E., 2002, In: Structure. 10, 5, p. 629-637 9 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
1997
Specific binding of Hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: Calorimetric and spectroscopic studies
Haq, I., Ladbury, J. E., Chowdhry, B. Z., Jenkins, T. C. & Chaires, J. B., Aug 15 1997, In: Journal of Molecular Biology. 271, 2, p. 244-257 14 p.Research output: Contribution to journal › Article › peer-review
294 Scopus citations -
2006
Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90
Cliff, M. J., Harris, R., Barford, D., Ladbury, J. E. & Williams, M. A., Mar 2006, In: Structure. 14, 3, p. 415-426 12 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
2008
The Thermodynamics of Protein-Ligand Interaction and Solvation: Insights for Ligand Design
Olsson, T. S. G., Williams, M. A., Pitt, W. R. & Ladbury, J. E., Dec 26 2008, In: Journal of Molecular Biology. 384, 4, p. 1002-1017 16 p.Research output: Contribution to journal › Article › peer-review
265 Scopus citations -
2005
H-NS is a part of a thermally controlled mechanism for bacterial gene regulation
Ono, S., Goldberg, M. D., Olsson, T., Esposito, D., Hinton, J. C. D. & Ladbury, J. E., Oct 15 2005, In: Biochemical Journal. 391, 2, p. 203-213 11 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
2001
Inhibitors to the Src SH2 domain: A lesson in structure-thermodynamic correlation in drug design
Henriques, D. A. & Ladbury, J. E., Jun 15 2001, In: Archives of Biochemistry and Biophysics. 390, 2, p. 158-168 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
2003
Specificity is complex and time consuming: Mutual exclusivity in tyrosine kinase-mediated signaling
O'Rourke, L. & Ladbury, J. E., Jun 1 2003, In: Accounts of Chemical Research. 36, 6, p. 410-416 7 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
2000
Structural basis for recognition of dipeptides by peptide transporters
Payne, J. W., Grail, B. M., Gupta, S., Ladbury, J. E., Marshall, N. J., O’Brien, R. & Payne, G. M., Dec 1 2000, In: Archives of Biochemistry and Biophysics. 384, 1, p. 9-23 15 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
2011
Histone deacetylases 1, 6 and 8 are critical for invasion in breast cancer
Park, S. Y., Jun, J. I. A. E., Jeong, K. J., Heo, H. J., Sohn, J. S., Lee, H. Y., Park, C. G. & Kang, J., Jun 2011, In: Oncology reports. 25, 6, p. 1677-1681 5 p.Research output: Contribution to journal › Article › peer-review
152 Scopus citations -
2019
Reply to the Letter to the Editor “Regarding: Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation with Conformal External Beam Radiotherapy or Single-Entry Multilumen Intracavitary Brachytherapy”
Stecklein, S. R. & Bloom, E. S., Mar 2019, In: Practical radiation oncology. 9, 2, p. 60 1 p.Research output: Contribution to journal › Editorial › peer-review
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1991
Lack of nuclear RB protein staining in G0/middle G1 cells: Correlation to changes in total RB protein level
Xu, H. J., Hu, S. X. & Benedict, W. F., Jul 1991, In: Oncogene. 6, 7, p. 1139-1146 8 p.Research output: Contribution to journal › Article › peer-review
115 Scopus citations -
1979
The treatment of established micrometastases with syngeneic macrophages.
Fidler, I. J., Fogler, W. E., Barnes, Z. & Fisher, K., 1979, In: Advances in experimental medicine and biology. 121 B, p. 399-410 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2000
Photobiology of Monodelphis domestica
Ley, R. D., Reeve, V. E. & Kusewitt, D. F., Jul 1 2000, In: Developmental and Comparative Immunology. 24, 5, p. 503-516 14 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
1997
Carcinoid tumors of the lung and family history of cancer
Perkins, P., Lee, J. R. J., Kemp, B. L. & Cox, J. D., 1997, In: Journal of clinical epidemiology. 50, 6, p. 705-709 5 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
1976
Naltrexone: Physiological and psychological effects of single doses
Gritz, E. R., Shiffman, S. M., Jarvik, M. E., Sehlesinger, J. & Charuvastra, V. C., Jun 1976, In: Clinical pharmacology and therapeutics. 19, 6, p. 773-776 4 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2014
Chemopreventive efficacy of Aegle marmelos on murine transplantable tumors
George, S. K., Radhakrishnan, R., Kumar S., S., Sreelekha, T. T. & Balaram, P., Jan 2014, In: Integrative cancer therapies. 13, 1, p. 68-78 11 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1989
Pitfalls in multimodality imaging in a patient undergoing evaluation for bone marrow transplantation
Podoloff, D. A. & Kim, E. E., 1989, In: Clinical nuclear medicine. 14, 1, p. 32-35 4 p.Research output: Contribution to journal › Article › peer-review
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2009
Small Bowel Tumors: Diagnosis: Molecular biology of small bowel tumors
Sagiv, E., Adelson, K., Neugut, A. I. & Arber, N., Jan 14 2009, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach. Blackwell Publishing Ltd, p. 200-202 3 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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1988
Simultaneous Determination of Uranium and HNO3Concentrations in Solution by Laser-Induced Fluorescence Spectroscopy
Fujimori, H., Matsui, T. & Suzuki, K., Oct 1988, In: Journal of Nuclear Science and Technology. 25, 10, p. 798-804 7 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2001
Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene
Guan, B., Yue, P., Clayman, G. L. & Sun, S. Y., 2001, In: Journal of Cellular Physiology. 188, 1, p. 98-105 8 p.Research output: Contribution to journal › Article › peer-review
115 Scopus citations -
1982
Involvement of Macrophages in the Eradication of Established Metastases following Intravenous Injection of Liposomes Containing Macrophage Activators
Fidler, I. J., Barnes, Z., Fogler, W. E., Kirsh, R., Bugelski, P. & Poste, G., Feb 1 1982, In: Cancer Research. 42, 2, p. 496-501 6 p.Research output: Contribution to journal › Article › peer-review
181 Scopus citations -
1986
The activation of tumoricidal properties in human blood monocytes by muramyl dipeptide requires specific intracellular interaction
Fogler, W. E. & Fidler, I. J., 1986, In: Journal of Immunology. 136, 6, p. 2311-2317 7 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
2016
Pilonidal sinus disease guidelines: a minefield?
Doll, D., Luedi, M. M. & Wysocki, A. P., Apr 1 2016, In: Techniques in Coloproctology. 20, 4, p. 263-264 2 p.Research output: Contribution to journal › Letter › peer-review
5 Scopus citations -
2003
Imaging with 99mTc ECDG targeted at the multifunctional glucose transport system: Feasibility study with rodents
Yang, D. J., Kim, C. G., Schechter, N. R., Azhdarinia, A., Yu, D. F., Oh, C. S., Bryant, J. L., Won, J. J., Kim, E. E. & Podoloff, D. A., Feb 1 2003, In: Radiology. 226, 2, p. 465-473 9 p.Research output: Contribution to journal › Article › peer-review
142 Scopus citations -
1983
Leiomyosarcoma of the penis
McDonald, M. W., O'Connell, J. R., Manning, J. T. & Benjamin, R. S., 1983, In: Journal of Urology. 130, 4, p. 788-789 2 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1995
Genetic disparity between morphologically benign cysts contiguous to ovarian carcinomas and solitary cystadenomas
Zheng, J., Benedict, W. F., Xu, H. J., Hu, S. X., Kim, T. M., Velicescu, M., Wan, M., Cofer, K. F. & Dubeau, L., Aug 2 1995, In: Journal of the National Cancer Institute. 87, 15, p. 1146-1153 8 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
1996
Expression of the retinoblastoma (RB) tumor suppressor gene inhibits tumor cell invasion in vitro
Li, J., Hu, S. X., Perng, G. S., Zhou, Y., Xu, K., Zhang, C., Seigne, J., Benedict, W. F. & Xu, H. J., 1996, In: Oncogene. 13, 11, p. 2379-2386 8 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
1981
Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide
Fidler, I. J., Sone, S., Fogler, W. E. & Barnes, Z. L., 1981, In: Proceedings of the National Academy of Sciences of the United States of America. 78, 3 I, p. 1680-1684 5 p.Research output: Contribution to journal › Article › peer-review
Open Access293 Scopus citations -
1990
The retinoblastoma gene: Its role in human malignancies
Benedict, W. F., Xu, H. J. & Takahashi, R., 1990, In: Cancer Investigation. 8, 5, p. 535-540 6 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
1994
Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma
Xu, H. J., Quinlan, D. C., Davidson, A. G., Hu, S. X., Summers, C. L., Li, J. & Benedict, W. F., May 4 1994, In: Journal of the National Cancer Institute. 86, 9, p. 695-699 5 p.Research output: Contribution to journal › Article › peer-review
137 Scopus citations -
Loss of Heterozygosity on Chromosome 13 Is Common Only in the Biologically More Aggressive Subtypes of Ovarian Epithelial Tumors and Is Associated with Normal Retinoblastoma Gene Expression
Kirn, T. M., Benedict, W. F., Xu, H. J., Hu, S. X., Gosewehr, J., Velicescu, M., Yin, E., Zheng, J., D'Ablaing, G. & Dubeau, L., Feb 1994, In: Cancer Research. 54, 3, p. 605-609 5 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
1991
Correction method for fluorescence reduction using time-resolved fluorometry and spectrophotometry
Matsui, T., Suzuki, K., Sakagami, M. & Kitamori, T., 1991, In: Applied Spectroscopy. 45, 1, p. 32-35 4 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
1998
Role of insulin-like growth factor-I (IGF-I) receptor, IGF-I, and IGF binding protein-2 in human colorectal cancers
Mishra, L., Bass, B., Ooi, B. S., Sidawy, A., Korman, L. & Monig, H., 1998, In: Growth Hormone and IGF Research. 8, 6, p. 473-479 7 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
2017
Arterial-Portal Fistula After Percutaneous Liver Biopsy in Hepatic Allograft Causing Hemobilia and Pancreatitis
Zhang, D. S., Metwalli, Z. & Hussain, K. B., Jan 1 2017, In: Clinical Gastroenterology and Hepatology. 15, 1, p. e3-e4Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations