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Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia
Kuang, S. Q., Bai, H., Fang, Z. H., Lopez, G., Yang, H., Tong, W., Wang, Z. Z. & Garcia-Manero, G., Mar 25 2010, In: Blood. 115, 12, p. 2412-2419 8 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
Murai, M., Toyota, M., Satoh, A., Suzuki, H., Akino, K., Mita, H., Sasaki, Y., Ishida, T., Shen, L., Garcia-Manero, G., Issa, J. P. J., Hinoda, Y., Tokino, T. & Imai, K., Mar 28 2005, In: British journal of cancer. 92, 6, p. 1165-1172 8 p.Research output: Contribution to journal › Article › peer-review
95 Scopus citations -
Aberrant DNA methylation in pediatric patients with acute lymphocytic leukemia
Garcia-Manero, G., Jeha, S., Daniel, J., Williamson, J., Albitar, M., Kantarjian, H. M. & Issa, J. P. J., Feb 1 2003, In: Cancer. 97, 3, p. 695-702 8 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
Jiang, Y., Dunbar, A., Gondek, L. P., Mohan, S., Rataul, M., O'Keefe, C., Sekeres, M., Saunthararajah, Y. & Maciejewski, J. P., Feb 5 2009, In: Blood. 113, 6, p. 1315-1325 11 p.Research output: Contribution to journal › Article › peer-review
Open Access364 Scopus citations -
Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia
Jelinek, J., Gharibyan, V., Estecio, M. R. H., Kondo, K., He, R., Chung, W., Lu, Y., Zhang, N., Liang, S., Kantarjian, H. M., Cortes, J. E. & Issa, J. P. J., 2011, In: PloS one. 6, 7, e22110.Research output: Contribution to journal › Article › peer-review
98 Scopus citations -
Aberrant DNA methylation of a cell cycle regulatory pathway composed of P73, P15 and P57KIP2 is a rare event in children with acute lymphocytic leukemia
Canalli, A. A., Yang, H., Jeha, S., Hoshino, K., Sanchez-Gonzalez, B., Brandt, M., Pierce, S., Kantarjian, H., Issa, J. P. & Garcia-Manero, G., Aug 2005, In: Leukemia Research. 29, 8, p. 881-885 5 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia
Shen, L. L., Toyota, M., Kondo, Y., Obata, T., Daniel, S., Pierce, S., Imai, K., Kantarjian, H. M., Issa, J. P. J. & Garcia-Manero, G., May 15 2003, In: Blood. 101, 10, p. 4131-4136 6 p.Research output: Contribution to journal › Article › peer-review
116 Scopus citations -
Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia
Hoshino, K., Quintás-Cardama, A., Yang, H., Sanchez-Gonzalez, B. & Garcia-Manero, G., May 2007, In: Leukemia. 21, 5, p. 906-911 6 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Aberrant DNA methylation predicts melanoma-specific survival in patients with acral melanoma
Pradhan, D., Jour, G., Milton, D., Vasudevaraja, V., Tetzlaff, M. T., Nagarajan, P., Curry, J. L., Ivan, D., Long, L., Ding, Y., Ezhilarasan, R., Sulman, E. P., Diab, A., Hwu, W. J., Prieto, V. G., Torres-Cabala, C. A. & Aung, P. P., Dec 2019, In: Cancers. 11, 12, 2031.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice
Chin, S. S., Romano, R. A., Nagarajan, P., Sinha, S. & Garrett-Sinha, L. A., Dec 15 2013, In: Biology Open. 2, 12, p. 1336-1345 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer
Amann, J., Kalyankrishna, S., Massion, P. P., Ohm, J. E., Girard, L., Shigematsu, H., Peyton, M., Juroske, D., Huang, Y., Salmon, J. S., Kim, Y. H., Pollack, J. R., Yanagisawa, K., Gazdar, A., Minna, J. D., Kurie, J. M. & Carbone, D. P., Jan 1 2005, In: Cancer Research. 65, 1, p. 226-235 10 p.Research output: Contribution to journal › Article › peer-review
397 Scopus citations -
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q
Zhou, L., Opalinska, J., Sohal, D., Yu, Y., Mo, Y., Bhagat, T., Abdel-Wahab, O., Fazzari, M., Figueroa, M., Alencar, C., Zhang, J., Kambhampati, S., Parmar, S., Nischal, S., Hueck, C., Suzuki, M., Freidman, E., Pellagatti, A., Boultwood, J., Steidl, U., & 10 others , Jul 15 2011, In: Journal of Biological Chemistry. 286, 28, p. 25211-25223 13 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
Aberrant Epigenetic Modifications in Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Park, I. Y., Sohn, B. H., Yu, E., Suh, D. J., Chung, Y. H., Lee, J. H., Surzycki, S. J. & Lee, Y. I., Apr 2007, In: Gastroenterology. 132, 4, p. 1476-1494 19 p.Research output: Contribution to journal › Article › peer-review
Open Access280 Scopus citations -
Aberrant epigenetic reprogramming of imprinted microRNA-127 and Rtl1 in cloned mouse embryos
Cui, X. S., Zhang, D. X., Ko, Y. G. & Kim, N. H., Feb 6 2009, In: Biochemical and biophysical research communications. 379, 2, p. 390-394 5 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Aberrant EVI1 expression in acute myeloid leukemias associated with the t(3;8)(q26;q24)
Lennon, P. A., Abruzzo, L. V., Medeiros, L. J., Cromwell, C., Zhang, X., Yin, C. C., Kornblau, S. M., Konopieva, M. & Lin, P., Aug 2007, In: Cancer Genetics and Cytogenetics. 177, 1, p. 37-42 6 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth
Cook, D. R., Kang, M., Martin, T. D., Galanko, J. A., Loeza, G. H., Trembath, D. G., Justilien, V., Pickering, K. A., Vincent, D. F., Jarosch, A., Jurmeister, P., Waters, A. M., Hibshman, P. S., Campbell, A. D., Ford, C. A., Keku, T. O., Yeh, J. J., Lee, M. S., Cox, A. D., Fields, A. P., & 5 others , Jan 1 2021, In: Cancer Research. 82, 1, p. 90-104 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Aberrant expression of anaplastic lymphoma kinase in ovarian carcinoma independent of gene rearrangement
Tang, S., Yang, F., Du, X., Lu, Y., Zhang, L. & Zhou, X., 2016, In: International Journal of Gynecological Pathology. 35, 4, p. 337-347 11 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Aberrant expression of BCL2A1-restricted minor histocompatibility antigens in melanoma cells: Application for allogeneic transplantation
Torikai, H., Akatsuka, Y., Yatabe, Y., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Jun 2008, In: International journal of hematology. 87, 5, p. 467-473 7 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Aberrant expression of CD54 detected by flow cytometry is a characteristic of B-lymphoma cells in bone marrow specimens
Wang, W., Li, Y., Ali, H., Zhao, L., Mei, D., Hu, W. & Jiang, B., Dec 2021, In: BMC cancer. 21, 1, 1315.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis
Tandon, N., Goller, K., Wang, F., Soibam, B., Gagea, M., Jain, A. K., Schwartz, R. J. & Liu, Y., Dec 2019, In: EBioMedicine. 50, p. 55-66 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Aberrant expression of FLI-1 in melanoma
Ramani, N., Aung, P. P., Hwu, W. J., Nagarajan, P., Tetzlaff, M. T., Curry, J. L., Ivan, D., Prieto, V. G. & Torres-Cabala, C. A., Sep 2017, In: Journal of cutaneous pathology. 44, 9, p. 790-793 4 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Aberrant expression of gland-type gastric mucin in the surface epithelium of Helicobacter pylori-infected patients
Byrd, J. C., Yan, P., Sternberg, L., Yunker, C. K., Scheiman, J. M. & Bresalier, R. S., 1997, In: Gastroenterology. 113, 2, p. 455-464 10 p.Research output: Contribution to journal › Article › peer-review
114 Scopus citations -
Aberrant expression of HMB-45 in traumatized melanocytic nevi
Leleux, T. M., Prieto, V. G. & Diwan, A. H., Sep 2012, In: Journal of the American Academy of Dermatology. 67, 3, p. 446-450 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Aberrant expression of homeobox gene HOXA7 is associated with müllerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response
Naora, H., Montz, F. J., Chai, C. Y. & Roden, R. B. S., Dec 18 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 26, p. 15209-15214 6 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Aberrant expression of HOX genes in human invasive breast carcinoma.
Makiyama, K., Hamada, J. I., Takada, M., Murakawa, K., Takahashi, Y., Tada, M., Tamoto, E., Shindo, G., Matsunaga, A., Teramoto, K. I., Komuro, K., Kondo, S., Katoh, H., Koike, T. & Moriuchi, T., Apr 2005, In: Oncology reports. 13, 4, p. 673-679 7 p.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Aberrant expression of HOX genes in oral dysplasia and squamous cell carcinoma tissues
Hassan, N. M. M., Hamada, J. I., Murai, T., Seino, A., Takahashi, Y., Tada, M., Zhang, X., Kashiwazaki, H., Yamazaki, Y., Inoue, N. & Moriuchi, T., 2006, In: Oncology research. 16, 5, p. 217-224 8 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma
Dien Bard, J., Gelebart, P., Anand, M., Amin, H. M. & Lai, R., 2008, In: Leukemia. 22, 8, p. 1595-1603 9 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer
Ha, J. H., Yan, M., Gomathinayagam, R., Jayaraman, M., Husain, S., Liu, J., Mukherjee, P., Reddy, E. P., Song, Y. S. & Dhanasekaran, D. N., 2016, In: Oncotarget. 7, 45, p. 72845-72859 15 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Aberrant expression of katanin p60 in prostate cancer bone metastasis
Ye, X., Lee, Y. C., Choueiri, M., Chu, K., Huang, C. F., Tsai, W. W., Kobayashi, R., Logothetis, C. J., Yu-Lee, L. Y. & Lin, S. H., Feb 2012, In: Prostate. 72, 3, p. 291-300 10 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer
Shida, D., Watanabe, T., Aoki, J., Hama, K., Kitayama, J., Sonoda, H., Kishi, Y., Yamaguchi, H., Sasaki, S., Sako, A., Konishi, T., Arai, H. & Nagawa, H., Oct 2004, In: Laboratory Investigation. 84, 10, p. 1352-1362 11 p.Research output: Contribution to journal › Article › peer-review
Open Access125 Scopus citations -
Aberrant expression of maspin in idiopathic inflammatory bowel disease is associated with disease activity and neoplastic transformation
Cao, D., Wilentz, R. E., Abbruzzese, J. L., Ho, L. & Maitra, A., Aug 2005, In: International Journal of Gastrointestinal Cancer. 36, 1, p. 39-46 8 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Aberrant expression of p53, p21, cyclin D1, and Bcl2 and their clinicopathological correlation in ampullary adenocarcinoma
Guo, R., Overman, M., Chatterjee, D., Rashid, A., Shroff, S., Hua, W., Katz, M. H., Fleming, J. B., Varadhachary, G. R., Abbruzzese, J. L. & Wang, H., May 2014, In: Human Pathology. 45, 5, p. 1015-1023 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Aberrant Expression of p53 or the Epidermal Growth Factor Receptor Is Frequent in Early Bronchial Neoplasia, and Coexpression Precedes Squamous Cell Carcinoma Development
Rusch, V., Klimstra, D., Linkov, I. & Dmitrovsky, E., Mar 15 1995, In: Cancer Research. 55, 6, p. 1365-1372 8 p.Research output: Contribution to journal › Article › peer-review
136 Scopus citations -
Aberrant expression of proPTPRN2 in cancer cells confers resistance to apoptosis
Sorokin, A. V., Nair, B. C., Wei, Y., Aziz, K. E., Evdokimova, V., Hung, M. C. & Chen, J., May 1 2015, In: Cancer Research. 75, 9, p. 1846-1858 13 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters
He, Y., Zhou, Z., Hofstetter, W. L., Zhou, Y., Hu, W., Guo, C., Wang, L., Guo, W., Pataer, A., Correa, A. M., Lu, Y., Wang, J., Diao, L., Byers, L. A., Wistuba, I. I., Roth, J. A., Swisher, S. G., Heymach, J. V. & Fang, B., 2012, In: PloS one. 7, 2, e31087.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Aberrant expression of Smad4 results in resistance against the growth-inhibitory effect of transforming growth factor-β in the SiHa human cervical carcinoma cell line
Lee, S. H., Cho, Y. S., Shim, C. S., Kim, J. S., Choi, J. J., Oh, S. H., Kim, J. W., Zhang, W. & Lee, J. H., Nov 15 2001, In: International journal of cancer. 94, 4, p. 500-507 8 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Aberrant expression of the c-erbB-2/neu protooncogene in ovarian cancer
Hung, M. C., Zhang, X., Yan, D. H., Zhang, H. Z., He, G. P., Zhang, T. Q. & Shi, D. R., Jan 10 1992, In: Cancer Letters. 61, 2, p. 95-103 9 p.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
Aberrant expression of the dendritic cell marker tnfaip2 by the malignant cells of hodgkin lymphoma and primary mediastinal large b-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas
Kondratiev, S., Duraisamy, S., Unitt, C. L., Green, M. R., Pinkus, G. S., Shipp, M. A., Kutok, J. L., Drapkin, R. I. & Rodig, S. J., Oct 1 2011, In: American Journal of Surgical Pathology. 35, 10, p. 1531-1539 9 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Aberrant expression of the K-ras proto-oncogene in B-cell malignancies
Lee, J., Talpaz, M., Walters, R., Gutterman, J. U. & Blick, M., 1988, In: Hematologic pathology. 2, 4, p. 229-237 9 p.Research output: Contribution to journal › Article › peer-review
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Aberrant expression of tumor suppressor proteins in the Ewing family of tumors
Maitra, A., Roberts, H., Weinberg, A. G. & Geradts, J., 2001, In: Archives of Pathology and Laboratory Medicine. 125, 9, p. 1207-1212 6 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression
Li, M., Zhang, Y., Liu, Z., Bharadwaj, U., Wang, H., Wang, X., Zhang, S., Liuzzi, J. P., Chang, S. M., Cousins, R. J., Fisher, W. E., Brunicardi, F. C., Logsdon, C. D., Chen, C. & Yao, Q., Nov 20 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 47, p. 18636-18641 6 p.Research output: Contribution to journal › Article › peer-review
Open Access206 Scopus citations -
Aberrant expressions of HOX genes in colorectal and hepatocellular carcinomas
Kanai, M., Hamada, J. I., Takada, M., Asano, T., Murakawa, K., Takahashi, Y., Murai, T., Tada, M., Miyamoto, M., Kondo, S. & Moriuchi, T., Mar 2010, In: Oncology reports. 23, 3, p. 843-851 9 p.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
Aberrant FGFR tyrosine kinase signaling enhances the warburg effect by reprogramming LDH Isoform expression and activity in prostate cancer
Liu, J., Chen, G., Liu, Z., Liu, S., Cai, Z., You, P., Ke, Y., Lai, L., Huang, Y., Gao, H., Zhao, L., Pelicano, H., Huang, P., McKeehan, W. L., Wu, C. L., Wang, C., Zhong, W. & Wang, F., Aug 15 2018, In: Cancer Research. 78, 16, p. 4459-4470 12 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells
Dai, B., Kang, S. H., Gong, W., Liu, M., Aldape, K. D., Sawaya, R. & Huang, S., Sep 13 2007, In: Oncogene. 26, 42, p. 6212-6219 8 p.Research output: Contribution to journal › Article › peer-review
Open Access166 Scopus citations -
Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers
Kasembeli, M. M., Kaparos, E., Bharadwaj, U., Allaw, A., Khouri, A., Acot, B. & Tweardy, D. J., Mar 23 2023, In: Blood. 141, 12, p. 1411-1424 14 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis
Liao, Q., Liu, W., Liu, Y., Wang, F., Wang, C., Zhang, J., Chu, M., Jiang, D., Xiao, L., Shao, W., Sheng, Z., Tao, X., Huo, L., Cameron Yin, C., Zhang, Y., Lee, G., Huang, J., Li, Z. & Qiu, X., 2015, In: Oncotarget. 6, 37, p. 40081-40094 14 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Aberrant Hypermethylation Tumor Suppressor Genes in Pancreatic Endocrine Neoplasms
House, M. G., Herman, J. G., Guo, M. Z., Hooker, C. M., Schulick, R. D., Lillemoe, K. D., Cameron, J. L., Hruban, R. H., Maitra, A., Yeo, C. J., Eberlein, T. J. & Pitt, H. A., Sep 2003, In: Annals of surgery. 238, 3, p. 423-432 10 p.Research output: Contribution to journal › Article › peer-review
156 Scopus citations -
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Álvarez, E. G., Demeulemeester, J., Otero, P., Jolly, C., García-Souto, D., Pequeño-Valtierra, A., Zamora, J., Tojo, M., Temes, J., Baez-Ortega, A., Rodriguez-Martin, B., Oitaben, A., Bruzos, A. L., Martínez-Fernández, M., Haase, K., Zumalave, S., Abal, R., Rodríguez-Castro, J., Rodriguez-Casanova, A., Diaz-Lagares, A., & 23 others , Dec 2021, In: Nature communications. 12, 1, 6910.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas
Luo, S. Y., Sit, K. Y., Sihoe, A. D. L., Suen, W. S., Au, W. K., Tang, X., Ma, E. S. K., Chan, W. K., Wistuba, I. I., Minna, J. D., Tsao, G. S. W. & Lam, D. C. L., Aug 2014, In: Lung Cancer. 85, 2, p. 282-292 11 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Aberrant LPL expression, driven by STAT3, Mediates free fatty acid metabolism in cll cells
Rozovski, U., Grgurevic, S., Bueso-Ramos, C., Harris, D. M., Li, P., Liu, Z., Wu, J. Y., Jain, P., Wierda, W., Burger, J., O'Brien, S., Jain, N., Ferrajoli, A., Keating, M. J. & Estrov, Z., May 1 2015, In: Molecular Cancer Research. 13, 5, p. 944-953 10 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations