A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer

Tomohiro Kitahara; Ichiro Takemasa; Akira Inoue; Hideki Osawa; Masaaki Miyo; Yukako Mokutani; Hisataka Ogawa; Atsushi Naito; Atsushi Hamabe; Masayuki Hiraki; Koji Munakata; Mamoru Uemura; Junichi Nishimura; Taishi Hata; Tsunekazu Mizushima; Hirofumi Yamamoto; Yuichiro Doki; Masaki Mori

A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer

Tomohiro Kitahara, Ichiro Takemasa, Akira Inoue, Hideki Osawa, Masaaki Miyo, Yukako Mokutani, Hisataka Ogawa, Atsushi Naito, Atsushi Hamabe, Masayuki Hiraki, Koji Munakata, Mamoru Uemura, Junichi Nishimura, Taishi Hata, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori

Genomic Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

A 70-year-old man presenting with melena was referred to our clinic. A clinical examination revealed a bulky tumor in the lower rectum. After ileostomy, 4 courses of capecitabine plus oxaliplatin (XELOX) therapy were administered as neoadjuvant chemotherapy. Computed tomography (CT) revealed significant reduction of the tumor. Laparoscopic super-low anterior resection with lateral lymph node dissection was performed. The pathological examination revealed no residual cancer cells, and a diagnosis of pathological complete response was made. The patient has been disease-free for 1 year after the operation. Neoadjuvant chemotherapy with XELOX might be promising for patients with locally advanced rectal cancer.

Original language	English (US)
Pages (from-to)	1569-1571
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	41
Issue number	12
State	Published - Nov 2014

Keywords

Rectal cancer
XELOX

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

Kitahara, T., Takemasa, I., Inoue, A., Osawa, H., Miyo, M., Mokutani, Y., Ogawa, H., Naito, A., Hamabe, A., Hiraki, M., Munakata, K., Uemura, M., Nishimura, J., Hata, T., Mizushima, T., Yamamoto, H., Doki, Y., & Mori, M. (2014). A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer. Japanese Journal of Cancer and Chemotherapy, 41(12), 1569-1571.

Kitahara, T, Takemasa, I, Inoue, A, Osawa, H, Miyo, M, Mokutani, Y, Ogawa, H, Naito, A, Hamabe, A, Hiraki, M, Munakata, K, Uemura, M, Nishimura, J, Hata, T, Mizushima, T, Yamamoto, H, Doki, Y & Mori, M 2014, 'A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer', Japanese Journal of Cancer and Chemotherapy, vol. 41, no. 12, pp. 1569-1571.

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title = "A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer",

abstract = "A 70-year-old man presenting with melena was referred to our clinic. A clinical examination revealed a bulky tumor in the lower rectum. After ileostomy, 4 courses of capecitabine plus oxaliplatin (XELOX) therapy were administered as neoadjuvant chemotherapy. Computed tomography (CT) revealed significant reduction of the tumor. Laparoscopic super-low anterior resection with lateral lymph node dissection was performed. The pathological examination revealed no residual cancer cells, and a diagnosis of pathological complete response was made. The patient has been disease-free for 1 year after the operation. Neoadjuvant chemotherapy with XELOX might be promising for patients with locally advanced rectal cancer.",

keywords = "Rectal cancer, XELOX",

author = "Tomohiro Kitahara and Ichiro Takemasa and Akira Inoue and Hideki Osawa and Masaaki Miyo and Yukako Mokutani and Hisataka Ogawa and Atsushi Naito and Atsushi Hamabe and Masayuki Hiraki and Koji Munakata and Mamoru Uemura and Junichi Nishimura and Taishi Hata and Tsunekazu Mizushima and Hirofumi Yamamoto and Yuichiro Doki and Masaki Mori",

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T1 - A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer

AU - Kitahara, Tomohiro

AU - Takemasa, Ichiro

AU - Inoue, Akira

AU - Osawa, Hideki

AU - Miyo, Masaaki

AU - Mokutani, Yukako

AU - Ogawa, Hisataka

AU - Naito, Atsushi

AU - Hamabe, Atsushi

AU - Hiraki, Masayuki

AU - Munakata, Koji

AU - Uemura, Mamoru

AU - Nishimura, Junichi

AU - Hata, Taishi

AU - Mizushima, Tsunekazu

AU - Yamamoto, Hirofumi

AU - Doki, Yuichiro

AU - Mori, Masaki

PY - 2014/11

Y1 - 2014/11

N2 - A 70-year-old man presenting with melena was referred to our clinic. A clinical examination revealed a bulky tumor in the lower rectum. After ileostomy, 4 courses of capecitabine plus oxaliplatin (XELOX) therapy were administered as neoadjuvant chemotherapy. Computed tomography (CT) revealed significant reduction of the tumor. Laparoscopic super-low anterior resection with lateral lymph node dissection was performed. The pathological examination revealed no residual cancer cells, and a diagnosis of pathological complete response was made. The patient has been disease-free for 1 year after the operation. Neoadjuvant chemotherapy with XELOX might be promising for patients with locally advanced rectal cancer.

AB - A 70-year-old man presenting with melena was referred to our clinic. A clinical examination revealed a bulky tumor in the lower rectum. After ileostomy, 4 courses of capecitabine plus oxaliplatin (XELOX) therapy were administered as neoadjuvant chemotherapy. Computed tomography (CT) revealed significant reduction of the tumor. Laparoscopic super-low anterior resection with lateral lymph node dissection was performed. The pathological examination revealed no residual cancer cells, and a diagnosis of pathological complete response was made. The patient has been disease-free for 1 year after the operation. Neoadjuvant chemotherapy with XELOX might be promising for patients with locally advanced rectal cancer.

KW - Rectal cancer

KW - XELOX

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A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer

Abstract

Keywords

ASJC Scopus subject areas

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