Gastric adenocarcinoma in children and adolescents

Vivek Subbiah; Gauri Varadhachary; Cynthia E. Herzog; Winston W. Huh

doi:10.1002/pbc.23051

Gastric adenocarcinoma in children and adolescents

Vivek Subbiah, Gauri Varadhachary, Cynthia E. Herzog, Winston W. Huh

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.

Original language	English (US)
Pages (from-to)	524-527
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	57
Issue number	3
DOIs	https://doi.org/10.1002/pbc.23051
State	Published - Sep 2011

Keywords

Adolescents
Children
Gastric adenocarcinomas
Gastric cancer
Gastric carcinoma

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1002/pbc.23051

Cite this

@article{88566f1597e14406a8e07b437890e63b,

title = "Gastric adenocarcinoma in children and adolescents",

abstract = "Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.",

keywords = "Adolescents, Children, Gastric adenocarcinomas, Gastric cancer, Gastric carcinoma",

author = "Vivek Subbiah and Gauri Varadhachary and Herzog, {Cynthia E.} and Huh, {Winston W.}",

year = "2011",

month = sep,

doi = "10.1002/pbc.23051",

language = "English (US)",

volume = "57",

pages = "524--527",

journal = "Pediatric Blood and Cancer",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "3",

}

TY - JOUR

T1 - Gastric adenocarcinoma in children and adolescents

AU - Subbiah, Vivek

AU - Varadhachary, Gauri

AU - Herzog, Cynthia E.

AU - Huh, Winston W.

PY - 2011/9

Y1 - 2011/9

N2 - Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.

AB - Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.

KW - Adolescents

KW - Children

KW - Gastric adenocarcinomas

KW - Gastric cancer

KW - Gastric carcinoma

UR - http://www.scopus.com/inward/record.url?scp=79960177240&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960177240&partnerID=8YFLogxK

U2 - 10.1002/pbc.23051

DO - 10.1002/pbc.23051

M3 - Article

C2 - 21744476

AN - SCOPUS:79960177240

SN - 1545-5009

VL - 57

SP - 524

EP - 527

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 3

ER -

Gastric adenocarcinoma in children and adolescents

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this