TY - JOUR
T1 - National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research
T2 - challenges and recommended priorities
AU - Kim, Michelle M.
AU - Mehta, Minesh P.
AU - Smart, Dee Dee K.
AU - Steeg, Patricia S.
AU - Hong, Julie A.
AU - Espey, Michael G.
AU - Prasanna, Pataje G.
AU - Crandon, Laura
AU - Hodgdon, Christine
AU - Kozak, Niki
AU - Armstrong, Terri S.
AU - Morikawa, Aki
AU - Willmarth, Nicole
AU - Tanner, Kirk
AU - Boire, Adrienne
AU - Gephart, Melanie Hayden
AU - Margolin, Kim A.
AU - Hattangadi-Gluth, Jona
AU - Tawbi, Hussein
AU - Trifiletti, Daniel M.
AU - Chung, Caroline
AU - Basu-Roy, Upal
AU - Burns, Robyn
AU - Oliva, Isabella C.Glitza
AU - Aizer, Ayal A.
AU - Anders, Carey K.
AU - Davis, Joanne
AU - Ahluwalia, Manmeet S.
AU - Chiang, Veronica
AU - Li, Jing
AU - Kotecha, Rupesh
AU - Formenti, Silvia C.
AU - Ellingson, Benjamin M.
AU - Gondi, Vinai
AU - Sperduto, Paul W.
AU - Barnholtz-Sloan, Jill S.
AU - Rodon, Jordi
AU - Lee, Eudocia Q.
AU - Khasraw, Mustafa
AU - Yeboa, Debra Nana
AU - Brastianos, Priscilla K.
AU - Galanis, Evanthia
AU - Coleman, C. Norman
AU - Ahmed, Mansoor M.
N1 - Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023/8
Y1 - 2023/8
N2 - Brain metastases are an increasing global public health concern, even as survival rates improve for patients with metastatic disease. Both metastases and the sequelae of their treatment are key determinants of the inter-related priorities of patient survival, function, and quality of life, mandating a multidimensional approach to clinical care and research. At a virtual National Cancer Institute Workshop in September, 2022, key stakeholders convened to define research priorities to address the crucial areas of unmet need for patients with brain metastases to achieve meaningful advances in patient outcomes. This Policy Review outlines existing knowledge gaps, collaborative opportunities, and specific recommendations regarding consensus priorities and future directions in brain metastases research. Achieving major advances in research will require enhanced coordination between the ongoing efforts of individual organisations and consortia. Importantly, the continual and active engagement of patients and patient advocates will be necessary to ensure that the directionality of all efforts reflects what is most meaningful in the context of patient care.
AB - Brain metastases are an increasing global public health concern, even as survival rates improve for patients with metastatic disease. Both metastases and the sequelae of their treatment are key determinants of the inter-related priorities of patient survival, function, and quality of life, mandating a multidimensional approach to clinical care and research. At a virtual National Cancer Institute Workshop in September, 2022, key stakeholders convened to define research priorities to address the crucial areas of unmet need for patients with brain metastases to achieve meaningful advances in patient outcomes. This Policy Review outlines existing knowledge gaps, collaborative opportunities, and specific recommendations regarding consensus priorities and future directions in brain metastases research. Achieving major advances in research will require enhanced coordination between the ongoing efforts of individual organisations and consortia. Importantly, the continual and active engagement of patients and patient advocates will be necessary to ensure that the directionality of all efforts reflects what is most meaningful in the context of patient care.
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U2 - 10.1016/S1470-2045(23)00297-8
DO - 10.1016/S1470-2045(23)00297-8
M3 - Review article
C2 - 37541280
AN - SCOPUS:85166598153
SN - 1470-2045
VL - 24
SP - e344-e354
JO - The lancet oncology
JF - The lancet oncology
IS - 8
ER -