New insights about immune populations in gastrointestinal GvHD

Eiko Hayase; Robert R. Jenq

doi:10.1016/j.xcrm.2023.101126

New insights about immune populations in gastrointestinal GvHD

Eiko Hayase, Robert R. Jenq

Genomic Medicine

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Jarosch et al.¹ have deeply characterized immune cell infiltrates in gastrointestinal (GI) biopsies from individuals with GI graft-versus-host disease (GI-GvHD) using single-cell RNA sequencing and ChipCytometry. Individuals with severe GI-GvHD demonstrated increased clonally expanded cytotoxic CD8 T cells in GI biopsies.

Original language	English (US)
Article number	101126
Journal	Cell Reports Medicine
Volume	4
Issue number	7
DOIs	https://doi.org/10.1016/j.xcrm.2023.101126
State	Published - Jul 18 2023

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.xcrm.2023.101126

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title = "New insights about immune populations in gastrointestinal GvHD",

abstract = "Jarosch et al.1 have deeply characterized immune cell infiltrates in gastrointestinal (GI) biopsies from individuals with GI graft-versus-host disease (GI-GvHD) using single-cell RNA sequencing and ChipCytometry. Individuals with severe GI-GvHD demonstrated increased clonally expanded cytotoxic CD8 T cells in GI biopsies.",

author = "Eiko Hayase and Jenq, {Robert R.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

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doi = "10.1016/j.xcrm.2023.101126",

language = "English (US)",

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AU - Hayase, Eiko

AU - Jenq, Robert R.

PY - 2023/7/18

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N2 - Jarosch et al.1 have deeply characterized immune cell infiltrates in gastrointestinal (GI) biopsies from individuals with GI graft-versus-host disease (GI-GvHD) using single-cell RNA sequencing and ChipCytometry. Individuals with severe GI-GvHD demonstrated increased clonally expanded cytotoxic CD8 T cells in GI biopsies.

AB - Jarosch et al.1 have deeply characterized immune cell infiltrates in gastrointestinal (GI) biopsies from individuals with GI graft-versus-host disease (GI-GvHD) using single-cell RNA sequencing and ChipCytometry. Individuals with severe GI-GvHD demonstrated increased clonally expanded cytotoxic CD8 T cells in GI biopsies.

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DO - 10.1016/j.xcrm.2023.101126

M3 - Comment/debate

C2 - 37467719

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VL - 4

JO - Cell Reports Medicine

JF - Cell Reports Medicine

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New insights about immune populations in gastrointestinal GvHD

Abstract

ASJC Scopus subject areas

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