TY - JOUR
T1 - Perspectives in immunotherapy
T2 - meeting report from the “Immunotherapy Bridge” (December 4th–5th, 2019, Naples, Italy)
AU - Ascierto, Paolo A.
AU - Butterfield, Lisa H.
AU - Campbell, Katie
AU - Daniele, Bruno
AU - Dougan, Michael
AU - Emens, Leisha A.
AU - Formenti, Silvia
AU - Janku, Filip
AU - Khleif, Samir N.
AU - Kirchhoff, Tomas
AU - Morabito, Alessandro
AU - Najjar, Yana
AU - Nathan, Paul
AU - Odunsi, Kunle
AU - Patnaik, Akash
AU - Paulos, Chrystal M.
AU - Reinfeld, Bradley I.
AU - Skinner, Heath D.
AU - Timmerman, John
AU - Puzanov, Igor
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - Over the last few years, numerous clinical trials and real-world experience have provided a large amount of evidence demonstrating the potential for long-term survival with immunotherapy agents across various malignancies, beginning with melanoma and extending to other tumours. The clinical success of immune checkpoint blockade has encouraged increasing development of other immunotherapies. It has been estimated that there are over 3000 immuno-oncology trials ongoing, targeting hundreds of disease and immune pathways. Evolving topics on cancer immunotherapy, including the state of the art of immunotherapy across various malignancies, were the focus of discussions at the Immunotherapy Bridge meeting (4–5 December, 2019, Naples, Italy), and are summarised in this report.
AB - Over the last few years, numerous clinical trials and real-world experience have provided a large amount of evidence demonstrating the potential for long-term survival with immunotherapy agents across various malignancies, beginning with melanoma and extending to other tumours. The clinical success of immune checkpoint blockade has encouraged increasing development of other immunotherapies. It has been estimated that there are over 3000 immuno-oncology trials ongoing, targeting hundreds of disease and immune pathways. Evolving topics on cancer immunotherapy, including the state of the art of immunotherapy across various malignancies, were the focus of discussions at the Immunotherapy Bridge meeting (4–5 December, 2019, Naples, Italy), and are summarised in this report.
KW - Biomarkers
KW - Checkpoint inhibitors
KW - Combination therapy
KW - Immunotherapy
KW - Tumor microenvironment
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=85098760976&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098760976&partnerID=8YFLogxK
U2 - 10.1186/s12967-020-02627-y
DO - 10.1186/s12967-020-02627-y
M3 - Article
C2 - 33407605
AN - SCOPUS:85098760976
SN - 1479-5876
VL - 19
JO - Journal of translational medicine
JF - Journal of translational medicine
IS - 1
M1 - 13
ER -