Revealing the genomic heterogeneity of melanoma

Omar Kabbarah, Lynda Chin

Research output: Contribution to journalShort surveypeer-review

29 Scopus citations


The melanoma genome possesses numerous recurrent chromosomal rearrangements, and embedded within this complexity are clues critical to disease pathogenesis and response to therapy. High-resolution genome-wide DNA copy number approaches, in conjunction with gene-specific mutational analyses, appear poised to define keystone molecular events, provide more accurate classification schemes, and set the stage for the design of rational therapies that may finally have an impact on survival of this deadly disease.

Original languageEnglish (US)
Pages (from-to)439-441
Number of pages3
JournalCancer cell
Issue number6
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research


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