• 4048 Citations
  • 34 h-Index
1991 …2019
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Research Output 1991 2019

  • 4048 Citations
  • 34 h-Index
  • 113 Article
  • 5 Letter
  • 4 Review article
  • 1 Comment/debate
2019

Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma

George, B., George, S. K., Shi, W., Haque, A., Shi, P., Eskandari, G., Axelson, M., Larsson, O., Kaseb, A. O. & Amin, H. M., Jan 1 2019, In : Journal of Hematology and Oncology. 12, 1, 80.

Research output: Contribution to journalArticle

Open Access
T-Cell Lymphoma
Lymphoma
Neoplasms
IGF Type 1 Receptor
Protein-Tyrosine Kinases
2018
2 Citations (Scopus)
Lymphoproliferative Disorders
Natural Killer Cells
Mutation
Immunophenotyping
Rare Diseases

Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma

Pestana, R. C., Hassan, M. M., Ali, R. A. H., Abugabal, Y. I., Girard, L. M., Li, D., Chang, P., Raghav, K. P. S., Morris, J., Wolff, R. A., Rashid, A., Amin, H. & Kaseb, A., Dec 1 2018, In : Oncotarget. 9, 102, p. 37721-37732 12 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Angiopoietin-1
Hepatocellular Carcinoma
Survival
Confidence Intervals
2 Citations (Scopus)

Involvement of oncogenic tyrosine kinase NPM-ALK in trifluoperazine-induced cell cycle arrest and apoptosis in ALK + anaplastic large cell lymphoma

Hu, L., Zhang, X., Wang, J., Wang, S., Amin, H. & Shi, P., May 28 2018, In : Hematology. 23, 5, p. 284-290 7 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Trifluoperazine
Cell Cycle Checkpoints
Protein-Tyrosine Kinases
Apoptosis
6 Citations (Scopus)
Philadelphia Chromosome
Myelodysplastic Syndromes
Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Therapeutics
2017
4 Citations (Scopus)

Downregulation of HADH promotes gastric cancer progression via Akt signaling pathway

Shen, C., Song, Y. H., Xie, Y., Wang, X., Wang, Y., Wang, C., Liu, S., Xue, S. L., Li, Y., Liu, B., Tang, Z., Chen, W., Song, J., Amin, H. M. & Zhou, J., Jan 1 2017, In : Oncotarget. 8, 44, p. 76279-76289 11 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Down-Regulation
Stomach
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Phosphatidylinositol 3-Kinases
16 Citations (Scopus)

GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery

Liu, Y., Zhu, S., Gu, K., Guo, Z., Huang, X., Wang, M., Amin, H., Zhu, W. & Shi, P., Sep 6 2017, In : ACS Applied Materials and Interfaces. 9, 35, p. 29496-29504 9 p.

Research output: Contribution to journalArticle

Podophyllotoxin
Pyrans
Prodrugs
Tumors
Infrared radiation

Natural history of T1N0M0 hepatocellular carcinoma: Large-scale study in the United States

Alshamsi, H. O., Ali, R. A. H., Hassan, M. M., Shalaby, A. S., Dahbour, I., Lacin, S., Mahvash, A., Odisio, B. C., Murthy, R., Avritscher, R., Abdelsalam, M. E., Rashid, A., Vauthey, J. N., Aloia, T. A., Conrad, C., Segraves, Y., Krishnan, S., Das, P., Koay, E. J., Amin, H. & 2 others, Yao, J. C. & Kaseb, A., Sep 1 2017, In : Oncology (Switzerland). 93, 4, p. 233-242 10 p.

Research output: Contribution to journalArticle

Natural History
Hepatocellular Carcinoma
Therapeutics
Survival
Hepatitis
4 Citations (Scopus)

TrkA is a binding partner of NPM-ALK that promotes the survival of ALK + T-cell lymphoma

Shi, W., George, S. K., George, B., Curry, C. V., Murzabdillaeva, A., Alkan, S. & Amin, H. M., Sep 2017, In : Molecular oncology. 11, 9, p. 1189-1207 19 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Survival
Cell Survival
Nerve Growth Factors
Nerve Growth Factor
10 Citations (Scopus)

Type I insulin-like growth factor receptor signaling in hematological malignancies

Vishwamitra, D., George, S. K., Shi, P., Kaseb, A. & Amin, H., Jan 1 2017, In : Oncotarget. 8, 1, p. 1814-1844 31 p.

Research output: Contribution to journalReview article

IGF Type 1 Receptor
Somatomedins
Hematologic Neoplasms
Plasma Cell Leukemia
Neoplasms
2016
14 Citations (Scopus)

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma

Mohanty, A., Sandoval, N., Das, M., Pillai, R., Chen, L., Chen, R. W., Amin, H. M., Wang, M., Marcucci, G., Weisenburger, D. D., Rosen, S. T., Pham, L. V. & Ngo, V. N., Jan 1 2016, In : Oncotarget. 7, 45, p. 73558-73572 15 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Protein Stability
Cyclin D1
Mutation
Proteins

Effect of Tyrosine Phosphorylation Sites of Oncogenic Protein NPM-ALK on Cell Cycle and Its Related Mechanisms

Hu, L. L., Zhen, H., Zhang, X. N., Zhou, L., Amin, H. & Shi, P., Aug 1 2016, In : Zhongguo shi yan xue ye xue za zhi. 24, 4, p. 1201-1205 5 p.

Research output: Contribution to journalArticle

Jurkat Cells
Tyrosine
Cell Cycle
HEK293 Cells
Phosphorylation
12 Citations (Scopus)

Evaluating clinical and prognostic implications of Glypican-3 in hepatocellular carcinoma

Kaseb, A. O., Hassan, M., Lacin, S., Abdel-Wahab, R., Amin, H. M., Shalaby, A., Wolff, R. A., Yao, J., Rashid, A., Vennapusa, B., Feng, J. & Ohtomo, T., Jan 1 2016, In : Oncotarget. 7, 43, p. 69916-69926 11 p.

Research output: Contribution to journalArticle

Glypicans
Hepatocellular Carcinoma
Confidence Intervals
Staining and Labeling
Survival
14 Citations (Scopus)

IGF-1R and mTOR blockade: Novel resistance mechanisms and synergistic drug combinations for ewing sarcoma

Lamhamedi-Cherradi, S. E., Menegaz, B. A., Ramamoorthy, V., Vishwamitra, D., Wang, Y., Maywald, R. L., Buford, A. S., Fokt, I., Skora, S., Wang, J., Naing, A., Lazar, A., Rohren, E. M., Daw Bitar, N., Subbiah, V., Benjamin, R. S., Ratan, R., Priebe, W., Mikos, A. G., Amin, H. & 1 others, Ludwig, J. A., Dec 1 2016, In : Journal of the National Cancer Institute. 108, 12, djw182.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Drug Combinations
Sirolimus
Phosphatidylinositol 3-Kinases
Drug Resistance
19 Citations (Scopus)
Colorectal Neoplasms
Exome
DNA
Biopsy
Neoplasms
8 Citations (Scopus)

Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs

Mitchell, J., Tinkey, P. T., Avritscher, R., Van Pelt, C., Eskandari, G., Konnath George, S., Xiao, L., Cressman, E., Morris, J. S., Rashid, A., Kaseb, A. O., Amin, H. M. & Uthamanthil, R., Aug 1 2016, In : Oncology (Switzerland). 91, 2, p. 90-100 11 p.

Research output: Contribution to journalArticle

Diethylnitrosamine
Swine
Hepatocellular Carcinoma
Liver
Neoplasms
2015
11 Citations (Scopus)

A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies

Irwin, M. E., Johnson, B. P., Manshouri, R., Amin, H. M. & Chandra, J., Jan 1 2015, In : Oncotarget. 6, 27, p. 23631-23646 16 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Protein-Tyrosine Kinases
Growth
Neoplasms
Glioblastoma
25 Citations (Scopus)
Chromosomes, Human, Pair 3
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chromosomes
Chromosome Aberrations
Protein-Tyrosine Kinases
5 Citations (Scopus)

SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein

Vishwamitra, D., Curry, C. V., Shi, P., Alkan, S. & Amin, H., Jan 1 2015, In : Neoplasia. 17, 9, p. 742-754 13 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
T-Cell Lymphoma
Proteins
Lymphoma
5 Citations (Scopus)

Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms

Yang, L., Zhang, S., George, S. K., Teng, R., You, X., Xu, M., Liu, H., Sun, X., Amin, H. M. & Shi, W., Jan 1 2015, In : Oncotarget. 6, 17, p. 14953-14969 17 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
T-Lymphocytes
Neoplasms
Amyloid Precursor Protein Secretases
Proteasome Inhibitors
12 Citations (Scopus)

The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK + T-cell lymphoma

Vishwamitra, D., Curry, C. V., Alkan, S., Song, Y. H., Gallick, G. E., Kaseb, A. O., Shi, P. & Amin, H. M., Feb 25 2015, In : Molecular cancer. 14, 1, 53.

Research output: Contribution to journalArticle

Ikaros Transcription Factor
T-Cell Lymphoma
Zinc Fingers
Insulin-Like Growth Factor I
Protein Isoforms
4 Citations (Scopus)

Validation of an IGF-CTP scoring system for assessing hepatic reserve in egyptian patients with hepatocellular carcinoma

Ali, R. A. H., Shehata, S., Hassan, M. M., Xiao, L., Lee, J-S., Cheung, S., Essa, H. H., Hassabo, H. M., Shalaby, A. S., Mosad, E., Raghav, K. P. S., Rashid, A., Wolff, R. A., Morris, J., Amin, H. & Kaseb, A., Jan 1 2015, In : Oncotarget. 6, 25, p. 21193-21207 15 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Liver
Demography
Somatomedins
Population
2014
22 Citations (Scopus)

3D tissue-engineered model of Ewing's sarcoma

Lamhamedi-Cherradi, S. E., Santoro, M., Ramammoorthy, V., Menegaz, B. A., Bartholomeusz, G., Iles, L. R., Amin, H. M., Livingston, J. A., Mikos, A. G. & Ludwig, J. A., Dec 15 2014, In : Advanced Drug Delivery Reviews. 79, p. 155-171 17 p.

Research output: Contribution to journalReview article

Ewing's Sarcoma
Extracellular Matrix
Neoplasms
Biomimetics
Precision Medicine
14 Citations (Scopus)

Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK+ anaplastic large cell lymphoma

Hamedani, F. S., Cinar, M., Mo, Z., Cervania, M. A., Amin, H. & Alkan, S., Jan 1 2014, In : Leukemia Research. 38, 4, p. 503-508 6 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Down-Regulation
Apoptosis
STAT3 Transcription Factor
Proteins
12 Citations (Scopus)

Inhibition of type i insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma

Huang, Z., Fang, Z., Zhen, H., Zhou, L., Amin, H. & Shi, P., Jan 1 2014, In : Leukemia and Lymphoma. 55, 8, p. 1876-1883 8 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
Cell Cycle Checkpoints
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Apoptosis
1 Citation (Scopus)
Antineoplastic Combined Chemotherapy Protocols
Anaplastic Large-Cell Lymphoma
Immunophenotyping
Genetic Translocation
Hematopoietic Stem Cell Transplantation
31 Citations (Scopus)

Loss of p53 and altered miR15-a/16-1→MCL-1 pathway in CLL: Insights from TCL1-Tg:p53-/- mouse model and primary human leukemia cells

Liu, J., Chen, G., Feng, L., Zhang, W., Pelicano, H., Wang, F., Ogasawara, M. A., Lu, W., Amin, H., Croce, C. M., Keating, M. J. & Huang, P., Jan 14 2014, In : Leukemia. 28, 1, p. 118-128 11 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Phenotype
Drug Resistance
B-Cell Leukemia
5 Citations (Scopus)

Requirement for Ssbp2 in hematopoietic stem cell maintenance and stress response

Li, J., Kurasawa, Y., Wang, Y., Dwyer, K. C., Klumpp, S. A., Liang, H., Tailor, R. C., Raymond, A. C., Estrov, Z., Brandt, S. J., Davis, R. E., Zweidler-McKay, P. A., Amin, H. & Nagarajan, L., Nov 1 2014, In : Journal of Immunology. 193, 9, p. 4654-4662 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Maintenance
Carrier Proteins
Acute Myeloid Leukemia
Bone Marrow
2 Citations (Scopus)

Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors

Yue, Y., Wang, Y., He, Y., Yang, S., Chen, Z., Wang, Y., Xing, S., Shen, C., Amin, H. M., Wu, D. & Song, Y. H., Mar 7 2014, In : PloS one. 9, 3, e90992.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
mitosis
apoptosis
cell lines
myeloma
31 Citations (Scopus)

Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab

Falchook, G. S., Wheler, J. J., Naing, A., Jackson, E. F., Janku, F., Hong, D., Ng, C. S., Tannir, N. M., Lawhorn, K. N., Huang, M., Angelo, L. S., Vishwamitra, D., Hess, K., Howard, A. N., Parkhurst, K. L., Amin, H. M. & Kurzrock, R., Jan 1 2014, In : Oncotarget. 5, 21, p. 10280-10292 13 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Therapeutics
Magnetic Resonance Imaging
Neoplasms
Proteasome Endopeptidase Complex
23 Citations (Scopus)

The ALK inhibitor ASP3026 eradicates NPM-ALK + T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model

George, S. K., Vishwamitra, D., Manshouri, R., Shi, P. & Amin, H. M., 2014, In : Oncotarget. 5, 14, p. 5750-5763 14 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
T-Cell Lymphoma
Heterografts
Lymphoma
Clinical Trials
15 Citations (Scopus)

The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia

Ma, H., Mallampati, S., Lu, Y., Sun, B., Wang, E., Leng, X., Gong, Y., Shen, H., Yin, C. C., Jones, D., Amin, H., You, M. J., Zweidler-McKay, P. A., Ma, Y., Kantarjian, H. M., Arlinghaus, R. B., Glassman, A. & Sun, X., Jan 1 2014, In : Haematologica. 99, 10, p. 1591-1598 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphoid Precursor Cells
Leukemia
Alleles
Cell Proliferation
2013

B lymphoblastic leukemia/lymphoma presenting as seventh cranial nerve palsy

Kamiya Matsuoka, C., Garciarena, P., Amin, H., Tremont-Lukats, I. W. & de Groot, J. F., Dec 2013, In : Neurology: Clinical Practice. 3, 6, p. 532-534 3 p.

Research output: Contribution to journalArticle

Cranial Nerve Diseases
Facial Nerve
Precursor Cell Lymphoblastic Leukemia-Lymphoma
73 Citations (Scopus)

Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis

Cinar, M., Hamedani, F. S., Mo, Z., Cinar, B., Amin, H. & Alkan, S., Oct 1 2013, In : Leukemia Research. 37, 10, p. 1271-1277 7 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Apoptosis
B-Cell Antigen Receptors
Cell Survival
B-Lymphocytes
119 Citations (Scopus)

Modeling Ewing sarcoma tumors in vitro with 3D scaffolds

Fong, E. L. S., Lamhamedi-Cherradi, S. E., Burdett, E., Ramamoorthy, V., Lazar, A., Kasper, F. K., Farach-Carson, M. C., Vishwamitra, D., Demicco, E. G., Menegaz, B. A., Amin, H., Mikos, A. G. & Ludwig, J. A., Apr 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6500-6505 6 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Somatomedin Receptors
Bone and Bones
Neoplasms
Preclinical Drug Evaluations
12 Citations (Scopus)

Molecular and functional characterizations of the association and interactions between nucleophosmin-anaplastic lymphoma Kinase and type I Insulin-like growth factor receptor

Shi, B., Vishwamitra, D., Gabrielle Granda, J., Whitton, T., Shi, P. & Amin, H., Jan 1 2013, In : Neoplasia (United States). 15, 6, p. 669-683 15 p.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
Mutation
nucleophosmin
anaplastic lymphoma kinase
T-Cell Lymphoma
18 Citations (Scopus)

NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism

Zhu, H., Vishwamitra, D., Curry, C. V., Manshouri, R., Diao, L., Khan, A. & Amin, H., May 1 2013, In : Journal of Pathology. 230, 1, p. 82-94 13 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
MicroRNAs
Up-Regulation
T-Cell Lymphoma
Lymphoma
2012
3 Citations (Scopus)
Systemic Mastocytosis
Multiple Myeloma
Mast Cells
CD30 Ligand
Neoplasms
13 Citations (Scopus)

Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia

Singh, M. M., Irwin, M. E., Gao, Y., Ban, K., Shi, P., Arlinghaus, R. B., Amin, H. M. & Chandra, J., Jul 1 2012, In : Cancer. 118, 13, p. 3433-3445 13 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
NADP
Oxidoreductases
Oncogenes
34 Citations (Scopus)

MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression

Vishwamitra, D., Li, Y., Wilson, D., Manshouri, R., Curry, C. V., Shi, B., Tang, X. M., Sheehan, A. M., Wistuba, I. I., Shi, P. & Amin, H., May 1 2012, In : American Journal of Pathology. 180, 5, p. 1772-1780 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
anaplastic lymphoma kinase
Anaplastic Large-Cell Lymphoma
Cell Line
2011
25 Citations (Scopus)

Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma

Vishwamitra, D., Shi, P., Wilson, D., Manshouri, R., Vega, F., Schlette, E. J. & Amin, H., Jun 1 2011, In : Haematologica. 96, 6, p. 874-880 7 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
IGF Type 1 Receptor
Protein-Tyrosine Kinases
Cell Line
Apoptosis

Sclerosing orbital pseudotumor with involvement of the optic nerve

Amin, H. M., Perilman, J. I., Close, T. W., Collins, S. L. & Thomas, C., Aug 1 2011, In : Clinical and Surgical Ophthalmology. 29, 8-9, p. 194-200 7 p.

Research output: Contribution to journalArticle

Orbital Pseudotumor
Optic Nerve
Plasma Cell Granuloma
Pain
Narcotics
2010
62 Citations (Scopus)

Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation

Singh, R. R., Kim, J. E., Davuluri, Y., Drakos, E., Cho-Vega, J. H., Amin, H. & Vega, F., Jan 1 2010, In : Leukemia. 24, 5, p. 1025-1036 12 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Cell Survival
Cell Proliferation
Neoplasms
B-Lymphocytes
15 Citations (Scopus)

Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukaemia cells

Shi, P., Chandra, J., Sun, X., Gergely, M., Cortes, J. E., Garcia-Manero, G., Arlinghaus, R. B., Lai, R. & Amin, H. M., Jun 1 2010, In : Journal of Cellular and Molecular Medicine. 14, 6 B, p. 1777-1792 16 p.

Research output: Contribution to journalArticle

Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cell Cycle Checkpoints
Protein-Tyrosine Kinases
Apoptosis
59 Citations (Scopus)

Response of histiocytoses to imatinib mesylate: Fire to ashes

Janku, F., Amin, H., Yang, D., Garrido-Laguna, I., Trent, J. C. & Kurzrock, R., Nov 1 2010, In : Journal of Clinical Oncology. 28, 31

Research output: Contribution to journalArticle

Drug Administration Schedule
Piperazines
Erdheim-Chester Disease
abl Genes
Platelet-Derived Growth Factor alpha Receptor
17 Citations (Scopus)

SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability

Wang, Y., Klumpp, S., Amin, H., Liang, H., Li, J., Estrov, Z., Zweidler-McKay, P. A., Brandt, S. J., Agulnick, A. & Nagarajan, L., May 27 2010, In : Oncogene. 29, 21, p. 3044-3053 10 p.

Research output: Contribution to journalArticle

Cell Differentiation
T-Lymphocytes
Gene Targeting
B-Cell Lymphoma
Thymocytes
7 Citations (Scopus)

Treatment of aggressive systemic mastocytosis with daclizumab

Quintás-Cardama, A., Amin, H., Kantarjian, H. M. & Verstovsek, S., 2010, In : Leukemia and Lymphoma. 51, 3, p. 540-542 3 p.

Research output: Contribution to journalLetter

Drug Administration Schedule
Systemic Mastocytosis
Antibodies, Monoclonal, Humanized
Immunoglobulin G
Bone Marrow
2009
37 Citations (Scopus)

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells

Shi, P., Lai, R., Lin, Q., Iqbal, A. S., Young, L. C., Kwak, L. W., Ford, R. J. & Amin, H. M., Nov 20 2009, In : Blood. 114, 2, p. 360-370 11 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
T-cells
Oncogenes
Protein-Tyrosine Kinases
Lymphoma
36 Citations (Scopus)

IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma

Bard, J. D., Gelebart, P., Anand, M., Zak, Z., Hegazy, S. A., Amin, H. & Lai, R., Jan 1 2009, In : American Journal of Pathology. 175, 2, p. 825-834 10 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Growth
Interleukins
Small Interfering RNA
Interleukin-21 Receptors
32 Citations (Scopus)

Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism

Gelebart, P., Zak, Z., Anand, M., Dien-Bard, J., Amin, H. & Lai, R., Jan 1 2009, In : Leukemia. 23, 10, p. 1836-1846 11 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Apoptosis
Interleukin-21 Receptors
interleukin-21
Oligonucleotide Array Sequence Analysis