NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers

T. A. Yap; N. Ngoi; E. E. Dumbrava; D. D. Karp; J. Rodon Ahnert; S. Fu; D. S. Hong; A. Naing; S. Pant; S. A. Piha-Paul; V. Subbiah; A. M. Tsimberidou; D. Dufner; J. Rhudy; S. Gore; S. P. Ivy; Y. Yuan; S. N. Westin; Gordon B Mills; F. Meric-Bernstam

doi:10.1016/S0959-8049(22)00822-X

NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers

T. A. Yap, N. Ngoi, E. E. Dumbrava, D. D. Karp, J. Rodon Ahnert, S. Fu, D. S. Hong, A. Naing, S. Pant, S. A. Piha-Paul, V. Subbiah, A. M. Tsimberidou, D. Dufner, J. Rhudy, S. Gore, S. P. Ivy, Y. Yuan, S. N. Westin, Gordon B Mills, F. Meric-Bernstam

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8 Scopus citations

Original language	English (US)
Pages (from-to)	S7
Journal	European Journal of Cancer
Volume	174
DOIs	https://doi.org/10.1016/S0959-8049(22)00822-X
State	Published - Oct 2022

ASJC Scopus subject areas

Oncology
Cancer Research

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Yap, T. A., Ngoi, N., Dumbrava, E. E., Karp, D. D., Rodon Ahnert, J., Fu, S., Hong, D. S., Naing, A., Pant, S., Piha-Paul, S. A., Subbiah, V., Tsimberidou, A. M., Dufner, D., Rhudy, J., Gore, S., Ivy, S. P., Yuan, Y., Westin, S. N., Mills, G. B., & Meric-Bernstam, F. (2022). NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers. European Journal of Cancer, 174, S7. https://doi.org/10.1016/S0959-8049(22)00822-X

NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers. / Yap, T. A.; Ngoi, N.; Dumbrava, E. E. et al.
In: European Journal of Cancer, Vol. 174, 10.2022, p. S7.

Research output: Contribution to journal › Article › peer-review

Yap, TA, Ngoi, N, Dumbrava, EE, Karp, DD, Rodon Ahnert, J , Fu, S , Hong, DS , Naing, A , Pant, S , Piha-Paul, SA, Subbiah, V, Tsimberidou, AM, Dufner, D, Rhudy, J, Gore, S, Ivy, SP, Yuan, Y , Westin, SN, Mills, GB & Meric-Bernstam, F 2022, 'NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers', European Journal of Cancer, vol. 174, pp. S7. https://doi.org/10.1016/S0959-8049(22)00822-X

Yap TA, Ngoi N, Dumbrava EE, Karp DD, Rodon Ahnert J , Fu S et al. NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers. European Journal of Cancer. 2022 Oct;174:S7. doi: 10.1016/S0959-8049(22)00822-X

Yap, T. A. ; Ngoi, N. ; Dumbrava, E. E. et al. / NCI10329 : Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers. In: European Journal of Cancer. 2022 ; Vol. 174. pp. S7.

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