Daniel E Frigo

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Daniel E Frigo

Professor

 https://orcid.org/0000-0002-0713-471X

    • 6767 Bertner Ave, Mitchell Basic Science Research Building

      77030 Houston

      United States

    Calculated based on number of publications stored in Pure and citations from Scopus
    20022024

    Research activity per year

    Search results

    • 2024

      Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity

      Awad, D., Cao, P. H. A., Pulliam, T. L., Spradlin, M., Subramani, E., Tellman, T. V., Ribeiro, C. F., Muzzioli, R., Jewell, B. E., Pakula, H., Ackroyd, J. J., Murray, M. M., Han, J. J., Leng, M., Jain, A., Piyarathna, B., Liu, J., Song, X., Zhang, J., Klekers, A. R., & 8 othersDrake, J. M., Ittmann, M. M., Coarfa, C., Piwnica-Worms, D., Farach-Carson, M. C., Loda, M., Eberlin, L. S. & Frigo, D. E., Mar 1 2024, In: Cancer Research. 84, 5, p. 703-724 22 p.

      Research output: Contribution to journal › Article › peer-review

    • 2023

      Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

      Xu, W., Qadir, M. M. F., Nasteska, D., Mota de Sa, P., Gorvin, C. M., Blandino-Rosano, M., Evans, C. R., Ho, T., Potapenko, E., Veluthakal, R., Ashford, F. B., Bitsi, S., Fan, J., Bhondeley, M., Song, K., Sure, V. N., Sakamuri, S. S. V. P., Schiffer, L., Beatty, W., Wyatt, R., & 15 othersFrigo, D. E., Liu, X., Katakam, P. V., Arlt, W., Buck, J., Levin, L. R., Hu, T., Kolls, J., Burant, C. F., Tomas, A., Merrins, M. J., Thurmond, D. C., Bernal-Mizrachi, E., Hodson, D. J. & Mauvais-Jarvis, F., May 30 2023, In: Cell Reports. 42, 5, 112529.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Cancer Cell-Extrinsic Roles for the Androgen Receptor in Prostate Cancer

      Hahn, A. W., Siddiqui, B. A., Leo, J., Dondossola, E., Basham, K. J., Miranti, C. K. & Frigo, D. E., Apr 17 2023, In: Endocrinology. 164, 6

      Research output: Contribution to journal › Review article › peer-review

      3 Scopus citations

    • Characterization of prostate cancer adrenal metastases: dependence upon androgen receptor signaling and steroid hormones

      Sakellakis, M. J., Hahn, A. W., Ramachandran, S., Zhang, M., Hoang, A., Song, J. H., Liu, J., Wang, F., Basu, H. S., Sheperd, P., Wang, X., Frigo, D. E., Lin, S. H., Panaretakis, T., Zhang, J., Navone, N., Troncoso, P., Logothetis, C. J. & Titus, M. A., Dec 2023, In: Prostate Cancer and Prostatic Diseases. 26, 4, p. 751-758 8 p.

      Research output: Contribution to journal › Article › peer-review

    • Editorial: Metabolic regulation under oxidative stress in cancer

      Subramani, E., Dominic, A., Bhattacharya, P. K., Frigo, D. E., Bederman, I. & Vaziri-Gohar, A., 2023, In: Frontiers in Oncology. 13, 1286086.

      Research output: Contribution to journal › Editorial › peer-review

      Open Access

    • SGC-CAMKK2-1: A Chemical Probe for CAMKK2

      Wells, C., Liang, Y., Pulliam, T. L., Lin, C., Awad, D., Eduful, B., O’Byrne, S., Hossain, M. A., Catta-Preta, C. M. C., Ramos, P. Z., Gileadi, O., Gileadi, C., Couñago, R. M., Stork, B., Langendorf, C. G., Nay, K., Oakhill, J. S., Mukherjee, D., Racioppi, L., Means, A. R., & 5 othersYork, B., McDonnell, D. P., Scott, J. W., Frigo, D. E. & Drewry, D. H., Jan 2023, In: Cells. 12, 2, 287.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Stranger Things: New Roles and Opportunities for Androgen Receptor in Oncology Beyond Prostate Cancer

      Leo, J., Dondossola, E., Basham, K. J., Wilson, N. R., Alhalabi, O., Gao, J., Kurnit, K. C., White, M. G., McQuade, J. L., Westin, S. N., Wellberg, E. A. & Frigo, D. E., 2023, In: Endocrinology. 164, 6, bqad071.

      Research output: Contribution to journal › Review article › peer-review

    • Subtype and Site Specific–Induced Metabolic Vulnerabilities in Prostate Cancer

      Mossa, F., Robesti, D., Sumankalai, R., Corey, E., Titus, M., Kang, Y., Zhang, J., Briganti, A., Montorsi, F., Vellano, C. P., Marszalek, J. R., Frigo, D. E., Logothetis, C. J., Gujral, T. S. & Dondossola, E., Jan 1 2023, In: Molecular Cancer Research. 21, 1, p. 51-61 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • The Androgen Receptor Does Not Directly Regulate the Transcription of DNA Damage Response Genes

      Hasterok, S., Scott, T. G., Roller, D. G., Spencer, A., Dutta, A. B., Sathyan, K. M., Frigo, D. E., Guertin, M. J. & Gioeli, D., Jan 1 2023, In: Molecular Cancer Research. 21, 12, p. 1329-1341 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
    • 2022

      Regulation and role of CAMKK2 in prostate cancer

      Pulliam, T. L., Goli, P., Awad, D., Lin, C., Wilkenfeld, S. R. & Frigo, D. E., Jun 2022, In: Nature Reviews Urology. 19, 6, p. 367-380 14 p.

      Research output: Contribution to journal › Article › peer-review

      14 Scopus citations

    • Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer

      Pulliam, T., Awad, D., Han, J., Murray, M., Ackroyd, J., Goli, P., Oakhill, J., Scott, J., Ittmann, M. & Frigo, D. E., Jun 1 2022, In: Cells. 11, 12, 1890.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations
    • 2021

      A simple quantitative PCR assay to determine TRAMP transgene zygosity

      Chen, R., Liang, X., Murray, M. M., Karasik, E., Han, J. J., Zhu, M., Foster, B. A., Frigo, D. E. & Wang, G., Jun 2021, In: Prostate Cancer and Prostatic Diseases. 24, 2, p. 358-361 4 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

      Eduful, B. J., O'Byrne, S. N., Temme, L., Asquith, C. R. M., Liang, Y., Picado, A., Pilotte, J. R., Hossain, M. A., Wells, C. I., Zuercher, W. J., Catta-Preta, C. M. C., Zonzini Ramos, P., Santiago, A. D. S., Couñago, R. M., Langendorf, C. G., Nay, K., Oakhill, J. S., Pulliam, T. L., Lin, C., Awad, D., & 4 othersWillson, T. M., Frigo, D. E., Scott, J. W. & Drewry, D. H., Aug 12 2021, In: Journal of Medicinal Chemistry. 64, 15, p. 10849-10877 29 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling

      Lin, C., Blessing, A. M., Pulliam, T. L., Shi, Y., Wilkenfeld, S. R., Han, J. J., Murray, M. M., Pham, A. H., Duong, K., Brun, S. N., Shaw, R. J., Ittmann, M. M. & Frigo, D. E., Mar 4 2021, In: Oncogene. 40, 9, p. 1690-1705 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      32 Scopus citations

    • Mitochondria in Metabolic Syndrome, Reproduction and Transgenerational Inheritance-Ongoing Debates and Emerging Links

      Subramani, E. & Frigo, D. E., Jan 1 2021, In: Endocrinology. 162, 1, bqaa182.

      Research output: Contribution to journal › Comment/debate › peer-review

      Open Access
      1 Scopus citations

    • Nuclear receptors: From molecular mechanisms to therapeutics

      Frigo, D. E., Bondesson, M. & Williams, C., Nov 2021, In: Essays in Biochemistry. 65, 6, p. 847-856 10 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      38 Scopus citations

    • Roles of the tumor suppressor inhibitor of growth family member 4 (ING4) in cancer

      Shatnawi, A., Abu Rabe, D. I. & Frigo, D. E., Jan 2021, Advances in Cancer Research. Tew, K. D. & Fisher, P. B. (eds.). Academic Press Inc., p. 225-262 38 p. (Advances in Cancer Research; vol. 152).

      Research output: Chapter in Book/Report/Conference proceeding › Chapter

      4 Scopus citations

    • Steroid Hormones and Receptors in Health and Disease: A Research Conference Co-Organized by FASEB and the International Committee on Rapid Responses to Steroid Hormones (RRSH), May 25-27, 2021

      Barton, M., Frigo, D. E., Madak-Erdogan, Z., Mauvais-Jarvis, F. & Prossnitz, E. R., Nov 2021, In: FASEB Journal. 35, 11, e21858.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
    • 2020

      Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

      Dahl, H. C., Kanchwala, M., Thomas-Jardin, S. E., Sandhu, A., Kanumuri, P., Nawas, A. F., Xing, C., Lin, C., Frigo, D. E. & Delk, N. A., Dec 2020, In: PloS one. 15, 12 December, e0242970.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations
    • 2019

      Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Alters Hyperpolarized Pyruvate to Lactate Conversion and Lactate Levels In Vivo

      Zacharias, N., Lee, J., Ramachandran, S., Shanmugavelandy, S., McHenry, J., Dutta, P., Millward, S., Gammon, S., Efstathiou, E., Troncoso, P., Frigo, D. E., Piwnica-Worms, D., Logothetis, C. J., Maity, S. N., Titus, M. A. & Bhattacharya, P., Feb 15 2019, In: Molecular Imaging and Biology. 21, 1, p. 86-94 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Assessing therapeutic efficacy in real-time by hyperpolarized magnetic resonance metabolic imaging

      Dutta, P., Salzillo, T. C., Pudakalakatti, S., Gammon, S. T., Kaipparettu, B. A., McAllister, F., Wagner, S., Frigo, D. E., Logothetis, C. J., Zacharias, N. M. & Bhattacharya, P. K., Apr 2019, In: Cells. 8, 4, 340.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Prostate Cancer Energetics and Biosynthesis

      Lin, C., Salzillo, T. C., Bader, D. A., Wilkenfeld, S. R., Awad, D., Pulliam, T. L., Dutta, P., Pudakalakatti, S., Titus, M., McGuire, S. E., Bhattacharya, P. K. & Frigo, D. E., 2019, Advances in Experimental Medicine and Biology. Springer, p. 185-237 53 p. (Advances in Experimental Medicine and Biology; vol. 1210).

      Research output: Chapter in Book/Report/Conference proceeding › Chapter

      Open Access
      15 Scopus citations
    • 2018

      Communication between genomic and non-genomic signaling events coordinate steroid hormone actions

      Wilkenfeld, S. R., Lin, C. & Frigo, D. E., May 2018, In: Steroids. 133, p. 2-7 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      72 Scopus citations

    • Delineation of the androgen-regulated signaling pathways in prostate cancer facilitates the development of novel therapeutic approaches

      Awad, D., Pulliam, T. L., Lin, C., Wilkenfeld, S. R. & Frigo, D. E., Aug 2018, In: Current Opinion in Pharmacology. 41, p. 1-11 11 p.

      Research output: Contribution to journal › Review article › peer-review

      9 Scopus citations

    • GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling

      White, M. A., Tsouko, E., Lin, C., Rajapakshe, K., Spencer, J. M., Wilkenfeld, S. R., Vakili, S. S., Pulliam, T. L., Awad, D., Nikolos, F., Reddy Katreddy, R., Abraham Kaipparettu, B., Sreekumar, A., Zhang, X., Cheung, E., Coarfa, C. & Frigo, D. E., Apr 2018, In: Endocrine-related cancer. 25, 4, p. 453-469 17 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      39 Scopus citations

    • Organelle-derived acetyl-CoA promotes prostate cancer cell survival, migration, and metastasis via activation of calmodulin Kinase II

      Yu, G., Cheng, C. J., Lin, S. C., Lee, Y. C., Frigo, D. E., Yu-Lee, L. Y., Gallick, G. E., Titus, M. A., Nutt, L. K. & Lin, S. H., May 15 2018, In: Cancer Research. 78, 10, p. 2490-2502 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      25 Scopus citations

    • Regulation of SLC1A4 and SLC1A5 in prostate cancer-response

      White, M. A. & Frigo, D. E., Nov 2018, In: Molecular Cancer Research. 16, 11, p. 1811-1812 2 p.

      Research output: Contribution to journal › Letter › peer-review

      Open Access
      4 Scopus citations
    • 2017

      A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer

      Khan, A. S. & Frigo, D. E., Mar 1 2017, In: Nature Reviews Urology. 14, 3, p. 164-180 17 p.

      Research output: Contribution to journal › Review article › peer-review

      50 Scopus citations

    • Glutamine transporters are targets of multiple oncogenic signaling pathways in prostate cancer

      White, M. A., Lin, C., Rajapakshe, K., Dong, J., Shi, Y., Tsouko, E., Mukhopadhyay, R., Jasso, D., Dawood, W., Coarfa, C. & Frigo, D. E., Aug 2017, In: Molecular Cancer Research. 15, 8, p. 1017-1028 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      59 Scopus citations

    • Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression

      Blessing, A. M., Rajapakshe, K., Reddy Bollu, L., Shi, Y., White, M. A., Pham, A. H., Lin, C., Jonsson, P., Cortes, C. J., Cheung, E., La Spada, A. R., Bast, R. C., Merchant, F. A., Coarfa, C. & Frigo, D. E., Mar 4 2017, In: Autophagy. 13, 3, p. 506-521 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      81 Scopus citations
    • 2016

      Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

      Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M., & 2,442 othersAit-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J. M., Bae, D. H., Bae, J. S., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, S. H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X. Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J. F., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P. A., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M. N., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Bénard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Böckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouché, M., Bouchecareilh, M., Boucher, M. J., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M. M., Brancolini, C., Braus, G. H., Bravo-San-Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M. A., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burmeister, M., Bütikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A. M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A. I., Ceña, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H. J., Chagin, A. S., Chai, C. Y., Chakrabarti, G., Chamilos, G., Chan, E. Y. W., Chan, M. T. V., Chandra, D., Chandra, P., Chang, C. P., Chang, R. C. C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C. J., Chen, G., Chen, G. C., Chen, G., Chen, H., Chen, J. W., Chen, J. K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S. D., Chen, S., Chen, S. S. L., Chen, W., Chen, W. J., Chen, W. Q., Chen, W., Chen, X., Chen, Y. H., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y., Chen, Y. J., Chen, Y. Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S. G., Chiacchiera, F., Chiang, H. L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L. S., Chiong, M., Chiu, G. N. C., Cho, D. H., Cho, S. G., Cho, W. C., Cho, Y. Y., Cho, Y. S., Choi, A. M. K., Choi, E. J., Choi, E. K., Choi, J., Choi, M. E., Choi, S. I., Chou, T. F., Chouaib, S., Choubey, D., Choubey, V., Chow, K. C., Chowdhury, K., Chu, C. T., Chuang, T. H., Chun, T., Chung, H., Chung, T., Chung, Y. L., Chwae, Y. J., Cianfanelli, V., Ciarcia, R., Ciechomska, I. A., Ciriolo, M. R., Cirone, M., Claerhout, S., Clague, M. J., Cl� ria, J., Clarke, P. G. H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E. M., Cocco, T., Codogno, P., Coers, J., Cohen, E. E. W., Colecchia, D., Coletto, L., Coll, N. S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K. L., Coombs, G. H., Cooper, C. D., Cooper, J. M., Coppens, I., Corasaniti, M. T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M. D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S. L., Coto-Montes, A., Cottet, S., Couve, E., Covey, L. R., Cowart, L. A., Cox, J. S., Coxon, F. P., Coyne, C. B., Cragg, M. S., Craven, R. J., Crepaldi, T., Crespo, J. L., Criollo, A., Crippa, V., Cruz, M. T., Cuervo, A. M., Cuezva, J. M., Cui, T., Cutillas, P. R., Czaja, M. J., Czyzyk-Krzeska, M. F., Dagda, R. K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K. N., Valle, L. D., Dalmasso, G., D'amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V. M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C. R., Davey, H. M., Davids, L. M., Dávila, D., Davis, R. J., Dawson, T. M., Dawson, V. L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, R. C. B. Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G. R. Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J. P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D. P., Delage-Mourroux, R., Delbridge, L. M. D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C. J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T. P., Devenish, R. 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      Research output: Contribution to journal › Comment/debate › peer-review

      Open Access
      23 Scopus citations

    • Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

      Park, J. H., Vithayathil, S., Kumar, S., Sung, P. L., Dobrolecki, L. E., Putluri, V., Bhat, V. B., Bhowmik, S. K., Gupta, V., Arora, K., Wu, D., Tsouko, E., Zhang, Y., Maity, S., Donti, T. R., Graham, B. H., Frigo, D. E., Coarfa, C., Yotnda, P., Putluri, N., & 5 othersSreekumar, A., Lewis, M. T., Creighton, C. J., Wong, L. J. C. & Kaipparettu, B. A., Mar 8 2016, In: Cell Reports. 14, 9, p. 2154-2165 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      211 Scopus citations

    • Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

      Kaushik, A. K., Shojaie, A., Panzitt, K., Sonavane, R., Venghatakrishnan, H., Manikkam, M., Zaslavsky, A., Putluri, V., Vasu, V. T., Zhang, Y., Khan, A. S., Lloyd, S., Szafran, A. T., Dasgupta, S., Bader, D. A., Stossi, F., Li, H., Samanta, S., Cao, X., Tsouko, E., & 16 othersHuang, S., Frigo, D. E., Chan, L., Edwards, D. P., Kaipparettu, B. A., Mitsiades, N., Weigel, N. L., Mancini, M., McGuire, S. E., Mehra, R., Ittmann, M. M., Chinnaiyan, A. M., Putluri, N., Palapattu, G. S., Michailidis, G. & Sreekumar, A., May 19 2016, In: Nature communications. 7, 11612.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      64 Scopus citations
    • 2015

      Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy

      Gaur, S., Wen, Y., Song, J. H., Parikh, N. U., Mangala, L. S., Blessing, A. M., Ivan, C., Wu, S. Y., Varkaris, A., Shi, Y., Lopez-Berestein, G., Frigo, D. E., Sood, A. K. & Gallick, G. E., 2015, In: Oncotarget. 6, 30, p. 29161-29177 17 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      101 Scopus citations

    • Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

      Shafi, A. A., Putluri, V., Arnold, J. M., Tsouko, E., Maity, S., Roberts, J. M., Coarfa, C., Frigo, D. E., Putluri, N., Sreekumar, A. & Weigel, N. L., 2015, In: Oncotarget. 6, 31, p. 31997-32012 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      72 Scopus citations

    • Identification of a novel coregulator, SH3YL1, that interacts with the androgen receptor n-terminus

      Blessing, A. M., Ganesan, S., Rajapakshe, K., Sung, Y. Y., Bollu, L. R., Shi, Y., Cheung, E., Coarfa, C., Chang, J. T., McDonnell, D. P. & Frigo, D. E., Oct 2015, In: Molecular Endocrinology. 29, 10, p. 1426-1439 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      19 Scopus citations

    • miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene

      Tsouko, E., Wang, J., Frigo, D. E., Aydogdu, E. & Williams, C., Mar 24 2015, In: Carcinogenesis. 36, 9, p. 1051-1060 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      73 Scopus citations

    • Targeting the 5′-AMP-activated protein kinase and related metabolic pathways for the treatment of prostate cancer

      Popovics, P., Frigo, D. E., Schally, A. V. & Rick, F. G., May 1 2015, In: Expert Opinion on Therapeutic Targets. 19, 5, p. 617-632 16 p.

      Research output: Contribution to journal › Review article › peer-review

      22 Scopus citations
    • 2014

      Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch

      Tennakoon, J. B., Shi, Y., Han, J. J., Tsouko, E., White, M. A., Burns, A. R., Zhang, A., Xia, X., Ilkayeva, O. R., Xin, L., Ittmann, M. M., Rick, F. G., Schally, A. V. & Frigo, D. E., Nov 6 2014, In: Oncogene. 33, 45, p. 5251-5261 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      163 Scopus citations

    • Regulation of the pentose phosphate pathway by an androgen receptor-mTOR-mediated mechanism and its role in prostate cancer cell growth

      Tsouko, E., Khan, A. S., White, M. A., Han, J. J., Shi, Y., Merchant, F. A., Sharpe, M. A., Xin, L. & Frigo, D. E., Jan 1 2014, In: Oncogenesis. 3, 5, e103.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      115 Scopus citations
    • 2013

      Androgens promote prostate cancer cell growth through induction of autophagy

      Shi, Y., Han, J. J., Tennakoon, J. B., Mehta, F. F., Merchant, F. A., Burns, A. R., Howe, M. K., McDonnell, D. P. & Frigo, D. E., Feb 2013, In: Molecular Endocrinology. 27, 2, p. 280-295 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      73 Scopus citations

    • Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes

      Augello, M. A., Burd, C. J., Birbe, R., McNair, C., Ertel, A., Magee, M. S., Frigo, D. E., Wilder-Romans, K., Shilkrut, M., Han, S., Jernigan, D. L., Dean, J. L., Fatatis, A., McDonnell, D. P., Visakorpi, T., Feng, F. Y. & Knudsen, K. E., Jan 2 2013, In: Journal of Clinical Investigation. 123, 1, p. 493-508 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      38 Scopus citations
    • 2012

      Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha

      Collins-Burow, B. M., Antoon, J. W., Frigo, D. E., Elliott, S., Weldon, C. B., Boue, S. M., Beckman, B. S., Curiel, T. J., Alam, J., McLachlan, J. A. & Burow, M. E., Oct 2012, In: Journal of Steroid Biochemistry and Molecular Biology. 132, 1-2, p. 186-193 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      17 Scopus citations

    • Gαopotentiates estrogen receptor α activity via the ERK signaling pathway

      Bratton, M. R., WAntoon, J., Duong, B. N., Frigo, D. E., Tilghman, S., Collins-Burow, B. M., Elliott, S., Tang, Y., Melnik, L. I., Lai, L., Alam, J., Beckman, B. S., Hill, S. M., Rowan, B. G., McLachlan, J. A. & Burow, M. E., Jul 2012, In: Journal of Endocrinology. 214, 1, p. 45-54 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells

      Bratton, M. R., Frigo, D. E., Chris Segar, H., Nephew, K. P., McLachlan, J. A., Wiese, T. E. & Burow, M. E., Sep 2012, In: Environmental Health Perspectives. 120, 9, p. 1291-1296 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      29 Scopus citations
    • 2011

      CaM kinase kinase β-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

      Frigo, D. E., Howe, M. K., Wittmann, B. M., Brunner, A. M., Cushman, I., Wang, Q., Brown, M., Means, A. R. & McDonnell, D. P., Jan 15 2011, In: Cancer Research. 71, 2, p. 528-537 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      109 Scopus citations
    • 2009

      Glucose metabolism as a target of histone deacetylase inhibitors

      Wardell, S. E., Ilkayeva, O. R., Wieman, H. L., Frigo, D. E., Rathmell, J. C., Newgard, C. B. & McDonnell, D. P., Mar 2009, In: Molecular Endocrinology. 23, 3, p. 388-401 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      71 Scopus citations

    • Induction of Krüppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro

      Frigo, D. E., Sherk, A. B., Wittmann, B. M., Norris, J. D., Wang, Q., Joseph, J. D., Toner, A. P., Brown, M. & McDonnell, D. P., Sep 2009, In: Molecular Endocrinology. 23, 9, p. 1385-1396 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      58 Scopus citations

    • Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase

      Bratton, M. R., Frigo, D. E., Vigh-Conrad, K. A., Fan, D., Wadsworth, S., Mclachlan, J. A. & Burow, M. E., 2009, In: Carcinogenesis. 30, 1, p. 106-113 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      27 Scopus citations
    • 2008

      Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic

      Sherk, A. B., Frigo, D. E., Schnackenberg, C. G., Bray, J. D., Laping, N. J., Trizna, W., Hammond, M., Patterson, J. R., Thompson, S. K., Kazmin, D., Norris, J. D. & McDonnell, D. P., Sep 15 2008, In: Cancer Research. 68, 18, p. 7475-7483 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      178 Scopus citations