Jean Nicolas Vauthey

Professor

  • 43578 Citations
  • 105 h-Index
1984 …2019
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Research Output 1984 2019

2019
gemcitabine
Adenocarcinoma
Neoadjuvant Therapy
Carbohydrates
Antigens

Benign hepatic incidentalomas

Tran Cao, H. S., Marcal, L. P., Mason, M. C., Yedururi, S., Joechle, K., Wei, S. H. & Vauthey, J. N., Sep 1 2019, In : Current problems in surgery. 56, 9, 100642.

Research output: Contribution to journalArticle

Liver

Characteristics of atypical large well-differentiated hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma?

Okuno, M., Newhook, T. E., Joechle, K., Kawaguchi, Y., De Bellis, M., Tzeng, C. W. D., Chun, Y. S., Aloia, T. A., Shindoh, J., Kaseb, A. O. & Vauthey, J. N., Jan 1 2019, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Blood Vessels
Fibrosis
Liver Cell Adenoma
alpha-Fetoproteins
2 Citations (Scopus)
Propensity Score
Adenocarcinoma
Confidence Intervals
Drug Therapy
Lymph Nodes
2 Citations (Scopus)

Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer

Varkaris, A., Katsiampoura, A., Davis, J. S., Shah, N., Lam, M., Frias, R. L., Ivan, C., Shimizu, M., Morris, J., Menter, D., Overman, M., Tran, H., Heymach, J., Chun, Y. S., Vauthey, J. N., Calin, G. & Kopetz, S., Feb 5 2019, In : British journal of cancer. 120, 3, p. 340-345 6 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Inflammation
Recurrence
Survival
Interleukin-6
1 Citation (Scopus)

Conceptual framework of middle hepatic vein anatomy as a roadmap for safe right hepatectomy

Ogiso, S., Okuno, M., Shindoh, J., Sakamoto, Y., Mizuno, T., Araki, K., Goumard, C., Nomi, T., Ishii, T., Uemoto, S., Segraves, Y., Tzeng, C-W. D., Lee, J. E., Vauthey, J. N. & Conrad, C., Jan 1 2019, In : HPB. 21, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Hepatic Veins
Hepatectomy
Anatomy
Hemorrhage
Wounds and Injuries
5 Citations (Scopus)
Neoplasm Metastasis
Recurrence
Mutation
Survival
Liver

Contemporary analysis of complications associated with biliary stents during neoadjuvant therapy for pancreatic adenocarcinoma

Kim, B. J., Prakash, L. REKA., Narula, N., Davis, C. H., Kim, M., Aloia, T. A., Vauthey, J. N., Lee, J. E., Katz, M. H. & Tzeng, C-W. D., Jun 1 2019, In : HPB. 21, 6, p. 662-668 7 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Stents
Adenocarcinoma
Cholangitis
Pancreaticoduodenectomy
3 Citations (Scopus)

Dealing with an insufficient future liver remnant: Portal vein embolization and two-stage hepatectomy

Kawaguchi, Y., Lillemoe, H. A. & Vauthey, J. N., Apr 1 2019, In : Journal of surgical oncology. 119, 5, p. 594-603 10 p.

Research output: Contribution to journalReview article

Hepatectomy
Portal Vein
Liver
Neoplasm Metastasis
Drug Therapy
19 Citations (Scopus)

Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases

Chun, Y. S., Passot, G., Yamashita, S., Nusrat, M., Katsonis, P., Loree, J. M., Conrad, C., Tzeng, C. W. D., Xiao, L., Aloia, T. A., Eng, C., Kopetz, S. E., Lichtarge, O. & Vauthey, J. N., May 1 2019, In : Annals of surgery. 269, 5, p. 917-923 7 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Mutation
Liver
Survival
Genes
5 Citations (Scopus)
Opioid Analgesics
Habits
Education
Prescriptions
Surgical Oncology

Gene mutation and surgical technique: Suggestion or more?

Kawaguchi, Y., Lillemoe, H. A. & Vauthey, J. N., Jan 1 2019, In : Surgical Oncology.

Research output: Contribution to journalReview article

Mutation
Molecular Targeted Therapy
Neoplasm Metastasis
Genes
Liver
4 Citations (Scopus)

Hepatobiliary cancers, version 2.2019 featured updates to the NCCN guidelines

Benson, A. B., D'Angelica, M. I., Abbott, D. E., Abrams, T. A., Alberts, S. R., Anaya, D. A., Anders, R., Are, C., Brown, D., Chang, D. T., Cloyd, J., Covey, A. M., Hawkins, W., Iyer, R., Jacob, R., Karachristos, A., Kate Kelley, R., Kim, R., Palta, M., Park, J. O. & 11 others, Sahai, V., Schefter, T., Sicklick, J. K., Singh, G., Sohal, D., Stein, S., Gary Tian, G., Vauthey, J. N., Venook, A. P., Hammond, L. J. & Darlow, S. D., Apr 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 4, p. 302-310 9 p.

Research output: Contribution to journalArticle

Open Access
Guidelines
Gallbladder Neoplasms
Neoplasms
Liver Neoplasms
Bile Ducts
2 Citations (Scopus)

Impact of epidural analgesia on the systemic biomarker response after hepatic resection

Vicente, D., Patino, M., Marcus, R., Lillmoe, H., Limani, P., Newhook, T., Lee, A., Tzeng, C-W. D., Segraves, Y., Tweardy, D., Gottumukkala, V., Vauthey, J. N., Aloia, T. A. & Cata, J. P., Jan 1 2019, In : Oncotarget. 10, 5, p. 584-594 11 p.

Research output: Contribution to journalArticle

Epidural Analgesia
Patient-Controlled Analgesia
Biomarkers
Thorax
Liver

In Brief

Tran Cao, H. S., Marcal, L. P., Mason, M. C., Yedururi, S., Joechle, K., Wei, S. H. & Vauthey, J. N., Sep 2019, In : Current problems in surgery. 56, 9, 100643.

Research output: Contribution to journalComment/debate

Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors

Vega, E. A., Vinuela, E., Okuno, M., Joechle, K., Sanhueza, M., Diaz, C., Jarufe, N., Martinez, J., Troncoso, A., Diaz, A., Chun, Y. S., Tzeng, C. W. D., Lee, J. E., Vauthey, J. N. & Conrad, C., Aug 2019, In : HPB. 21, 8, p. 1046-1056 11 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Cholecystectomy
Survival
Neoplasms
Survival Rate
1 Citation (Scopus)

Inpatient Opioid Use After Pancreatectomy: Opportunities for Reducing Initial Opioid Exposure in Cancer Surgery Patients

Newhook, T. E., Dewhurst, W. L., Vreeland, T. J., Wang, X., Soliz, J., Speer, B. B., Hancher-Hodges, S., Feng, C., Bruno, M. L., Kim, M. P., Aloia, T. A., Vauthey, J. N., Lee, J. E., Katz, M. H. G. & Tzeng, C. W. D., Oct 1 2019, In : Annals of surgical oncology. 26, 11, p. 3428-3435 8 p.

Research output: Contribution to journalArticle

Pancreatectomy
Morphine
Opioid Analgesics
Inpatients
Pancreaticoduodenectomy

Interactions of multiple gene alterations in colorectal liver metastases

Kawaguchi, Y., Velasco, J. D., Arvide, E. M., Wei, S. H. & Vauthey, J. N., Jan 1 2019, In : Chinese Clinical Oncology. 8, 5, 50.

Research output: Contribution to journalReview article

Neoplasm Metastasis
Liver
Genes
p53 Genes
Survival
1 Citation (Scopus)
Neoplasm Metastasis
Recurrence
Survival
Liver
Drug Therapy

Intraoperative Air Leak Test to Prevent Bile Leak After Right Posterior Sectionectomy with En Bloc Diaphragm Resection for Metastatic Teratoma

Vreeland, T. J., Beaudry Simoneau, E., Dewhurst, W. L., Newhook, T. E., Westin, S. N., Mehran, R. J., Chun, Y. S., Aloia, T. A., Vauthey, J. N. & Tzeng, C. W. D., Aug 15 2019, In : Annals of surgical oncology. 26, 8, 1 p.

Research output: Contribution to journalArticle

Open Access
Teratoma
Diaphragm
Bile
Air
Liver
Neoadjuvant Therapy
Adenocarcinoma
Pathology
Pancreaticoduodenectomy
Survival

Long-term survival after post-hepatectomy liver failure for colorectal liver metastases

Joechle, K., Goumard, C., Vega, E. A., Okuno, M., Segraves, Y., Tzeng, C-W. D., Vauthey, J. N. & Conrad, C., Mar 1 2019, In : HPB. 21, 3, p. 361-369 9 p.

Research output: Contribution to journalArticle

Liver Failure
Hepatectomy
Neoplasm Metastasis
Survival
Liver
3 Citations (Scopus)

Loss of muscle mass during preoperative chemotherapy as a prognosticator for poor survival in patients with colorectal liver metastases

Okuno, M., Goumard, C., Kopetz, S., Vega, E. A., Joechle, K., Mizuno, T., Tzeng, C. W. D., Chun, Y. S., Lee, J. E., Vauthey, J. N., Aloia, T. A. & Conrad, C., Feb 2019, In : Surgery (United States). 165, 2, p. 329-336 8 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Drug Therapy
Muscles
Survival
Liver

Middle Hepatic Vein Roadmap for a Safe Laparoscopic Right Hepatectomy

Joechle, K., Vega, E. A., Okuno, M., Simoneau, E., Ogiso, S., Newhook, T. E., Ramirez, D. L., Holmes, A. A., Soliz, J. M., Chun, Y. S., Tzeng, C. W. D., Lee, J. E., Vauthey, J. N. & Conrad, C., Jan 15 2019, In : Annals of surgical oncology. 26, 1, 1 p.

Research output: Contribution to journalArticle

Hepatic Veins
Hepatectomy
Anatomy
Hemorrhage
Liver
5 Citations (Scopus)
Neoplasm Metastasis
Mutation
Liver
Survival
Recurrence

Opioid-Prescribing Practices after Oncologic Surgery: Opportunities for Improvement and a Call to Action

Newhook, T. E., Vreeland, T. J., Dewhurst, W. L., Arvide, E. M., Bruno, M. L., Robinson, K. A., Rajkot, N., Aloia, T. A., Katz, M. H. G., Vauthey, J. N., Lee, J. E. & Tzeng, C. W. D., Jan 1 2019, (Accepted/In press) In : Annals of surgery.

Research output: Contribution to journalArticle

Opioid Analgesics
1 Citation (Scopus)
Pancreaticoduodenectomy
Mesenteric Veins
Adenocarcinoma
Pancreatic Neoplasms
Inferior Vena Cava

Performance of a modified three-level classification in stratifying open liver resection procedures in terms of complexity and postoperative morbidity

Kawaguchi, Y., Hasegawa, K., Tzeng, C. W. D., Mizuno, T., Arita, J., Sakamoto, Y., Chun, Y. S., Aloia, T. A., Kokudo, N. & Vauthey, J. N., Jan 1 2019, (Accepted/In press) In : British Journal of Surgery.

Research output: Contribution to journalArticle

Hepatectomy
Morbidity
Liver
Tokyo
Segmental Mastectomy

Perioperative blood transfusions for vein resection during pancreaticoduodenectomy for pancreatic adenocarcinoma: Identification of clinical targets for optimization

Snyder, R. A., Prakash, L. R., Nogueras-Gonzalez, G. M., Kim, M. P., Aloia, T. A., Vauthey, J. N., Lee, J. E., Fleming, J. B., Katz, M. H. G. & Tzeng, C. W. D., Jul 2019, In : HPB. 21, 7, p. 841-848 8 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Blood Transfusion
Veins
Adenocarcinoma
Hemoglobins
1 Citation (Scopus)

Positive cystic duct margin at index cholecystectomy in incidental gallbladder cancer is an important negative prognosticator

Vega, E. A., Vinuela, E., Sanhueza, M., Mege, R., Caracci, M., Diaz, C., Diaz, A., Okuno, M., Joechle, K., Goumard, C., Segraves, Y., Tzeng, C-W. D., Lee, J. E., Vauthey, J. N. & Conrad, C., Jun 1 2019, In : European Journal of Surgical Oncology. 45, 6, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Cystic Duct
Cholecystectomy
Residual Neoplasm
Survival

Preoperative drainage for perihilar cholangiocarcinoma

Odisio, B. C., Krampitz, G. W., Murthy, R., Mahvash, A., Javle, M. & Vauthey, J. N., Jan 1 2019, In : The Lancet Gastroenterology and Hepatology. 4, 1, p. 10-11 2 p.

Research output: Contribution to journalLetter

Klatskin Tumor
Drainage
37 Citations (Scopus)

RAS Mutation Clinical Risk Score to Predict Survival after Resection of Colorectal Liver Metastases

Brudvik, K. W., Jones, R. P., Giuliante, F., Shindoh, J., Passot, G., Chung, M. H., Song, J., Li, L., Dagenborg, V. J., Fretland, Å. A., Røsok, B., De Rose, A. M., Ardito, F., Edwin, B., Panettieri, E., Larocca, L. M., Yamashita, S., Conrad, C., Aloia, T. A., Poston, G. J. & 2 others, Bjørnbeth, B. A. & Vauthey, J. N., Jan 1 2019, In : Annals of surgery. 269, 1, p. 120-126 7 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Mutation
Survival
Liver
Multivariate Analysis
2 Citations (Scopus)
Neoplasm Metastasis
Recurrence
Lung
Neoplasms
Confidence Intervals
1 Citation (Scopus)

Surgical Resection for Recurrence After Two-Stage Hepatectomy for Colorectal Liver Metastases Is Feasible, Is Safe, and Improves Survival

Lillemoe, H. A., Kawaguchi, Y., Passot, G., Karagkounis, G., Simoneau, E., You, Y-Q. N., Mehran, R. J., Segraves, Y., Tzeng, C-W. D., Aloia, T. A. & Vauthey, J. N., Jan 15 2019, In : Journal of Gastrointestinal Surgery. 23, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

Hepatectomy
Neoplasm Metastasis
Recurrence
Survival
Liver
3 Citations (Scopus)

The Prognostic Impact of KRAS Mutation in Patients Having Curative Resection of Synchronous Colorectal Liver Metastases

Goffredo, P., Utria, A. F., Beck, A. C., Chun, Y. S., Howe, J. R., Weigel, R. J., Vauthey, J. N. & Hassan, I., Oct 1 2019, In : Journal of Gastrointestinal Surgery. 23, 10, p. 1957-1963 7 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Mutation
Liver
Neoplasms
Survival
1 Citation (Scopus)

The role of preoperative therapy prior to pancreatoduodenectomy for distal cholangiocarcinoma

Cloyd, J. M., Prakash, L. REKA., Vauthey, J. N., Aloia, T. A., Segraves, Y., Tzeng, C-W. D., Kim, M., Lee, J. E. & Katz, M. H., Jul 1 2019, In : American Journal of Surgery. 218, 1, p. 145-150 6 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Cholangiocarcinoma
Therapeutics
Survival
Adenocarcinoma

Treatment Options for Metastatic Gastrointestinal Stromal Tumors to the Liver: A Review

Lillemoe, H. A., Brudvik, K. W. & Vauthey, J. N., Jan 1 2019, In : Seminars in Liver Disease. 39, 3, p. 395-402 8 p.

Research output: Contribution to journalReview article

Gastrointestinal Stromal Tumors
Liver
Therapeutics
Protein-Tyrosine Kinases
Survival Rate
2018
52 Citations (Scopus)

8th Edition of the AJCC Cancer Staging Manual: Pancreas and Hepatobiliary Cancers

Segraves, Y., Pawlik, T. M. & Vauthey, J. N., Apr 1 2018, In : Annals of surgical oncology. 25, 4, p. 845-847 3 p.

Research output: Contribution to journalEditorial

17 Citations (Scopus)

Ablation of colorectal liver metastasis: Interaction of ablation margins and RAS mutation profiling on local tumour progression-free survival

Calandri, M., Yamashita, S., Gazzera, C., Fonio, P., Veltri, A., Bustreo, S., Sheth, R. A., Yevich, S. M., Vauthey, J. N. & Odisio, B. C., Jul 1 2018, In : European Radiology. 28, 7, p. 2727-2734 8 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Neoplasm Metastasis
Mutation
Liver
Neoplasms
Neoplasm Metastasis
Drug Therapy
Liver
Therapeutics
1 Citation (Scopus)

ASO Author Reflections: RAS Mutations in Metastatic Colorectal Cancer

Passot, G., Vauthey, J. N. & Segraves, Y., Dec 17 2018, In : Annals of surgical oncology. 25, p. 850-851 2 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Mutation
13 Citations (Scopus)

Biomarkers in colorectal liver metastases

Yamashita, S., Segraves, Y., Kopetz, E. S. & Vauthey, J. N., May 1 2018, In : British Journal of Surgery. 105, 6, p. 618-627 10 p.

Research output: Contribution to journalReview article

Biomarkers
Neoplasm Metastasis
Liver
Mutation
Neoplasms
10 Citations (Scopus)
DNA Repair-Deficiency Disorders
Biliary Tract Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Cholangiocarcinoma
5 Citations (Scopus)

Comparison of early radiological predictors of outcome in patients with colorectal cancer with unresectable hepatic metastases treated with bevacizumab

Mazard, T., Boonsirikamchai, P., Overman, M. J., Asran, M. A., Choi, H., Herron, D., Eng, C., Maru, D. M., Ychou, M., Vauthey, J. N., Loyer, E. M. & Kopetz, E. S., Jan 1 2018, In : Gut. 67, 6, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasm Metastasis
Disease-Free Survival
Liver
oxaliplatin
2 Citations (Scopus)
Cholangiocarcinoma
Radiotherapy
Tumor Burden
Survival
Lymphopenia
22 Citations (Scopus)

Embryonic Origin of Primary Colon Cancer Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colon Cancer Liver Metastases

Yamashita, S., Brudvik, K. W., Kopetz, S. E., Maru, D., Clarke, C. N., Passot, G., Conrad, C., Chun, Y. S., Aloia, T. A. & Vauthey, J. N., Mar 1 2018, In : Annals of surgery. 267, 3, p. 514-520 7 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Colonic Neoplasms
Neoplasm Metastasis
Survival
Drug Therapy
1 Citation (Scopus)

Enhancing surgical performance by adopting expert musicians' practice and performance strategies

Rui, M., Lee, J. E., Vauthey, J. N. & Conrad, C., Apr 1 2018, In : Surgery (United States). 163, 4, p. 894-900 7 p.

Research output: Contribution to journalArticle

Performance Anxiety
Occupational Injuries
Diagnostic Self Evaluation
Functional Laterality
Wounds and Injuries

Evaluation of New Classifications for Liver Surgery

Tzeng, C-W. D. & Vauthey, J. N., Jan 1 2018, In : Annals of Surgery. 267, 1, p. 24-25 2 p.

Research output: Contribution to journalEditorial

5 Citations (Scopus)

Extended Lymphadenectomy Is Required for Incidental Gallbladder Cancer Independent of Cystic Duct Lymph Node Status

Vega, E. A., Vinuela, E., Yamashita, S., Sanhueza, M., Cavada, G., Diaz, C., Aloia, T. A., Segraves, Y., Tzeng, C-W. D., Okuno, M., Goumard, C., Vauthey, J. N., Lee, J. E. & Conrad, C., Jan 1 2018, In : Journal of Gastrointestinal Surgery. 22, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Cystic Duct
Lymph Node Excision
Lymph Nodes
Survival
1 Citation (Scopus)
Interventional Radiology
Hepatectomy
Portal Vein
Ligation
Liver