• 19873 Citations
  • 67 h-Index
1978 …2019
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Research Output 1978 2019

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Review article
2019

Current and future horizons of patient-derived xenograft models in colorectal cancer translational research

Inoue, A., Deem, A. K., Kopetz, S., Heffernan, T. P., Draetta, G. F. & Carugo, A., Sep 2019, In : Cancers. 11, 9, 1321.

Research output: Contribution to journalReview article

Open Access
Translational Medical Research
Heterografts
Colorectal Neoplasms
Clonal Evolution
Neoplasms
2018
25 Citations (Scopus)

Adaptive global innovative learning environment for glioblastoma: GBM AGILE

GBM AGILE Network, Feb 15 2018, In : Clinical Cancer Research. 24, 4, p. 737-743 7 p.

Research output: Contribution to journalReview article

Glioblastoma
Learning
Biomarkers
Therapeutics
Random Allocation
2017
60 Citations (Scopus)

Future cancer research priorities in the USA: a Lancet Oncology Commission

Jaffee, E. M., Dang, C. V., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., Barker, A. D., Bastani, R., Bhatia, S., Bluestone, J. A., Brawley, O., Butte, A. J., Coit, D. G., Davidson, N. E., Davis, M., DePinho, R. A., Diasio, R. B., Draetta, G., Frazier, A. L., Futreal, A. & 34 others, Gambhir, S. S., Ganz, P. A., Garraway, L., Gerson, S., Gupta, S., Heath, J., Hoffman, R. I., Hudis, C., Hughes-Halbert, C., Ibrahim, R., Jadvar, H., Kavanagh, B., Kittles, R., Le, Q. T., Lippman, S. M., Mankoff, D., Mardis, E. R., Mayer, D. K., McMasters, K., Meropol, N. J., Mitchell, B., Naredi, P., Ornish, D., Pawlik, T. M., Peppercorn, J., Pomper, M. G., Raghavan, D., Ritchie, C., Schwarz, S. W., Sullivan, R., Wahl, R., Wolchok, J. D., Wong, S. L. & Yung, A., Nov 2017, In : The lancet oncology. 18, 11, p. e653-e706

Research output: Contribution to journalReview article

Research
Neoplasms
Precision Medicine
Radiation Oncology
National Cancer Institute (U.S.)
2016
151 Citations (Scopus)

Genetics and biology of pancreatic ductal adenocarcinoma

Ying, H., Dey, P., Yao, W., Kimmelman, A. C., Draetta, G. F., Maitra, A. & Depinho, R. A., Feb 15 2016, In : Genes and Development. 30, 4, p. 355-385 31 p.

Research output: Contribution to journalReview article

Adenocarcinoma
Neoplasms
Molecular Models
Critical Pathways
Tumor Microenvironment
2015

Tumors and mitochondrial respiration: a neglected connection

Viale, A., Corti, D. & Draetta, G. F., Sep 15 2015, In : Cancer Research. 75, 18, p. 3685-3686 2 p.

Research output: Contribution to journalReview article

Respiration
Neoplasms
Multiple Drug Resistance
Glycolysis
Recurrence
63 Citations (Scopus)

Tumors and mitochondrial respiration: A neglected connection

Viale, A., Corti, D. & Draetta, G. F., Sep 15 2015, In : Cancer research. 75, 18, p. 3687-3691 5 p.

Research output: Contribution to journalReview article

Respiration
Neoplasms
Multiple Drug Resistance
Glycolysis
Recurrence
2004
148 Citations (Scopus)

Cdc25A phosphatase: Combinatorial phosphorylation, ubiquitylation and proteolysis

Busino, L., Chiesa, M., Draetta, G. F. & Donzelli, M., Mar 15 2004, In : Oncogene. 23, 11 REV. ISS. 1, p. 2050-2056 7 p.

Research output: Contribution to journalReview article

cdc25 Phosphatases
Ubiquitination
Proteolysis
Phosphorylation
Cell Cycle
2003
299 Citations (Scopus)

Regulating mammalian checkpoints through Cdc25 inactivation

Donzelli, M. & Draetta, G. F., Jul 1 2003, In : EMBO reports. 4, 7, p. 671-677 7 p.

Research output: Contribution to journalReview article

Chromosome Segregation
DNA Replication
Cell Cycle
Centrosome
Cyclin-Dependent Kinases
1997
177 Citations (Scopus)

Cdc25 protein phosphatases in cell proliferation

Draetta, G. & Eckstein, J., Apr 18 1997, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1332, 2, p. M53-M63

Research output: Contribution to journalReview article

37 Citations (Scopus)

Cell cycle: Will the real Cdk-activating kinase please stand up

Draetta, G., Jan 1 1997, In : Current Biology. 7, 1

Research output: Contribution to journalReview article

cyclin-dependent kinase
cell cycle
Cell Cycle
phosphotransferases (kinases)
Cells
1992
2 Citations (Scopus)

cdc2 protein kinase: structure-function relationships.

Marcote, M. J., Pagano, M. & Draetta, G., 1992, In : Ciba Foundation symposium. 170, p. 30-41; discussion 41-49

Research output: Contribution to journalReview article

CDC2 Protein Kinase
Cyclin A
Cyclins
Protein Kinases
Cell Cycle
1990
259 Citations (Scopus)

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

Draetta, G., Oct 1990, In : Trends in Biochemical Sciences. 15, 10, p. 378-383 6 p.

Research output: Contribution to journalReview article

Cell Cycle Checkpoints
Eukaryota
Phosphotransferases
Chemical activation
Cells
1988
395 Citations (Scopus)

Calcineurin.

Klee, C. B., Draetta, G. F. & Hubbard, M. J., 1988, In : Advances in enzymology and related areas of molecular biology. 61, p. 149-200 52 p.

Research output: Contribution to journalReview article

Calmodulin-Binding Proteins
Calcineurin
Phosphoprotein Phosphatases
Calmodulin
Calcium