Research output per year
Research output per year
- 20 results
Search results
-
2020
A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia
Shen, X., Wang, R., Kim, M. J., Hu, Q., Hsu, C. C., Yao, J., Klages-Mundt, N., Tian, Y., Lynn, E., Brewer, T. F., Zhang, Y., Arun, B., Gan, B., Andreeff, M., Takeda, S., Chen, J., Park, J. I., Shi, X., Chang, C. J., Jung, S. Y., & 2 others, Dec 17 2020, In: Molecular cell. 80, 6, p. 1013-1024.e6Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
C17orf53 is identified as a novel gene involved in inter-strand crosslink repair
Wang, C., Chen, Z., Su, D., Tang, M., Nie, L., Zhang, H., Feng, X., Wang, R., Shen, X., Srivastava, M., McLaughlin, M. E., Hart, T., Li, L. & Chen, J., Nov 2020, In: DNA Repair. 95, 102946.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress
Wang, R., Lenoir, W. F., Wang, C., Su, D., McLaughlin, M., Hu, Q., Shen, X., Tian, Y., Klages-Mundt, N., Lynn, E., Wood, R. D., Chen, J., Hart, T. & Li, L., Dec 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 52, p. 33436-33445 10 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks
Hu, Q., Klages-Mundt, N., Wang, R., Lynn, E., Kuma Saha, L., Zhang, H., Srivastava, M., Shen, X., Tian, Y., Kim, H., Ye, Y., Paull, T., Takeda, S., Chen, J. & Li, L., Jan 28 2020, In: Cell Reports. 30, 4, p. 1235-1245.e4Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2018
Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells
Kotlajich, M. V., Xia, J., Zhai, Y., Lin, H. Y., Bradley, C. C., Shen, X., Mei, Q., Wang, A. Z., Lynn, E. J., Shee, C., Chen, L. T., Li, L., Miller, K. M., Herman, C., Hastings, P. J. & Rosenberg, S. M., Dec 2018, In: DNA Repair. 72, p. 86-92 7 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2017
Constitutive role of the Fanconi anemia D2 gene in the replication stress response
Tian, Y., Shen, X., Wang, R., Klages-Mundt, N. L., Lynn, E. J., Martin, S. K., Ye, Y., Gao, M., Chen, J., Schlacher, K. & Li, L., Dec 8 2017, In: Journal of Biological Chemistry. 292, 49, p. 20184-20195 12 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2016
Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase
Xia, J., Chen, L. T., Mei, Q., Ma, C. H., Halliday, J. A., Lin, H. Y., Magnan, D., Pribis, J. P., Fitzgerald, D. M., Hamilton, H. M., Richters, M., Nehring, R. B., Shen, X., Li, L., Bates, D., Hastings, P. J., Herman, C., Jayaram, M. & Rosenberg, S. M., Nov 2016, In: Science Advances. 2, 11, e1601605.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
LIG4 mediates Wnt signalling-induced radioresistance
Jun, S., Jung, Y. S., Suh, H. N., Wang, W., Kim, M. J., Oh, Y. S., Lien, E. M., Shen, X., Matsumoto, Y., McCrea, P. D., Li, L., Chen, J. & Park, J. I., Mar 24 2016, In: Nature communications. 7, 10994.Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations -
Modularized Functions of the Fanconi Anemia Core Complex [Cell Reports 7, (2014), 1849-1857]
Huang, Y., Leung, J. W. C., Lowery, M., Matsushita, N., Wang, Y., Shen, X., Huong, D., Takata, M., Chen, J. & Li, L., Mar 22 2016, In: Cell Reports. 14, 11, p. 2761-2763 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
2015
UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold
Tian, Y., Paramasivam, M., Ghosal, G., Chen, D., Shen, X., Huang, Y., Akhter, S., Legerski, R., Chen, J., Seidman, M. M., Qin, J. & Li, L., Mar 31 2015, In: Cell Reports. 10, 12, p. 1957-1966 10 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
2014
Modularized Functions of the Fanconi Anemia Core Complex
Huang, Y., Leung, J. W. C., Lowery, M., Matsushita, N., Wang, Y., Shen, X., Huong, D., Takata, M., Chen, J. & Li, L., Jun 26 2014, In: Cell Reports. 7, 6, p. 1849-1857 9 p.Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
2013
Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress
Leung, J. W. C., Ghosal, G., Wang, W., Shen, X., Wang, J., Li, L. & Chen, J., Mar 1 2013, In: Journal of Biological Chemistry. 288, 9, p. 6342-6350 9 p.Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
2010
A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability
Yan, Z., Delannoy, M., Ling, C., Daee, D., Osman, F., Muniandy, P. A., Shen, X., Oostra, A. B., Du, H., Steltenpool, J., Lin, T., Schuster, B., Décaillet, C., Stasiak, A., Stasiak, A. Z., Stone, S., Hoatlin, M. E., Schindler, D., Woodcock, C. L., Joenje, H., & 8 others, Mar 26 2010, In: Molecular cell. 37, 6, p. 865-878 14 p.Research output: Contribution to journal › Article › peer-review
182 Scopus citations -
Mutagenic repair of DNA interstrand crosslinks
Shen, X. & Li, L., Jul 2010, In: Environmental and Molecular Mutagenesis. 51, 6, p. 493-499 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access32 Scopus citations -
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication
Xu, D., Muniandy, P., Leo, E., Yin, J., Thangavel, S., Shen, X., Ii, M., Agama, K., Guo, R., Fox, D., Meetei, A. R., Wilson, L., Nguyen, H., Weng, N. P., Brill, S. J., Li, L., Vindigni, A., Pommier, Y., Seidman, M. & Wang, W., Sep 2010, In: EMBO Journal. 29, 18, p. 3140-3155 16 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
2009
Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication
Shen, X., Do, H., Li, Y., Chung, W. H., Tomasz, M., de Winter, J. P., Xia, B., Elledge, S. J., Wang, W. & Li, L., Sep 11 2009, In: Molecular cell. 35, 5, p. 716-723 8 p.Research output: Contribution to journal › Article › peer-review
78 Scopus citations -
2008
Snm1B/Apollo mediates replication fork collapse and S phase checkpoint activation in response to DNA interstrand cross-links
Bae, J. B., Mukhopadhyay, S. S., Liu, L., Zhang, N., Tan, J., Akhter, S., Liu, X., Shen, X., Li, L. & Legerski, R. J., Aug 28 2008, In: Oncogene. 27, 37, p. 5045-5056 12 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
2006
REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA)
Shen, X., Jun, S., O'Neal, L. E., Sonoda, E., Bemark, M., Sale, J. E. & Li, L., May 19 2006, In: Journal of Biological Chemistry. 281, 20, p. 13869-13872 4 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
2005
The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links
Zhang, N., Kaur, R., Lu, X., Shen, X., Li, L. & Legerski, R. J., Dec 9 2005, In: Journal of Biological Chemistry. 280, 49, p. 40559-40567 9 p.Research output: Contribution to journal › Article › peer-review
107 Scopus citations -
2000
Ribosomal DNA its sequence analyses of Cnidium monnieri from different geographical origin in China
Cai, J., Zhou, K., Xu, L., Wang, Z., Shen, X., Wang, Y. & Li, X., Jan 2000, In: Yaoxue Xuebao. 35, 1, p. 56-59 4 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations