Find Research Outputs

2019

Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy

Caswell-Jin, J. L., McNamara, K., Reiter, J. G., Sun, R., Hu, Z., Ma, Z., Ding, J., Suarez, C. J., Tilk, S., Raghavendra, A., Forte, V., Chin, S. F., Bardwell, H., Provenzano, E., Caldas, C., Lang, J., West, R., Tripathy, D., Press, M. F. & Curtis, C., Dec 1 2019, In : Nature communications. 10, 1, 657.

Research output: Contribution to journalArticle

Open Access
breast
Tumors
therapy
tumors
Breast Neoplasms

Coffee, tea, and caffeine intake and amyotrophic lateral sclerosis mortality in a pooled analysis of eight prospective cohort studies

Petimar, J., O'Reilly, Adami, H. O., van den Brandt, P. A., Buring, J., English, D. R., Freedman, D. M., Giles, G. G., Håkansson, N., Kurth, T., Larsson, S. C., Robien, K., Schouten, L. J., Weiderpass, E. V., Wolk, A. & Smith-Warner, S. A., Mar 1 2019, In : European Journal of Neurology. 26, 3, p. 468-475 8 p.

Research output: Contribution to journalArticle

Coffee
Amyotrophic Lateral Sclerosis
Tea
Caffeine
Cohort Studies

Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

Sen, A., Papadimitriou, N., Lagiou, P., Perez-Cornago, A., Travis, R. C., Key, T. J., Murphy, N., Gunter, M., Freisling, H., Tzoulaki, I., Muller, D. C., Cross, A. J., Lopez, D. S., Bergmann, M., Boeing, H., Bamia, C., Kotanidou, A., Karakatsani, A., Tjønneland, A., Kyrø, C. & 27 othersOutzen, M., Redondo, M. L., Cayssials, V., Chirlaque, M. D., Barricarte, A., Sánchez, M. J., Larrañaga, N., Tumino, R., Grioni, S., Palli, D., Caini, S., Sacerdote, C., Bueno-de-Mesquita, B., Kühn, T., Kaaks, R., Nilsson, L. M., Landberg, R., Wallström, P., Drake, I., Bech, B. H., Overvad, K., Aune, D., Khaw, K. T., Riboli, E., Trichopoulos, D., Trichopoulou, A. & Tsilidis, K. K., Jan 15 2019, In : International Journal of Cancer. 144, 2, p. 240-250 11 p.

Research output: Contribution to journalArticle

Coffee
Tea
Prostatic Neoplasms
Confidence Intervals
Neoplasms

Cognate Interaction With CD4 + T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype

Eisel, D., Das, K., Dickes, E., König, R., Osen, W. & Eichmüller, S. B., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Macrophages
T-Lymphocytes
Phenotype
Neoplasms
Th1 Cells

Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial

Richard, N. M., Bernstein, L. J., Mason, W. P., Laperriere, N., Maurice, C., Millar, B. A., Shultz, D. B., Berlin, A. & Edelstein, K., Jan 1 2019, In : Journal of neuro-oncology.

Research output: Contribution to journalArticle

Brain Neoplasms
Rehabilitation
Randomized Controlled Trials
Health
Brain

Cohort Profile: The Finnish Health in Teens (Fin-HIT) study: A population-based study

Figueiredo, R. A. D. O., Simola-Ström, S., Rounge, T. B., Viljakainen, H., Eriksson, J. G., Roos, E. & Weiderpass, E. V., Feb 1 2019, In : International journal of epidemiology. 48, 1, p. 22-24H

Research output: Contribution to journalArticle

Open Access
Population
Adolescent Health

Colapso dinámico excesivo de la vía aérea o traquebroncomalacia: ¿es relevante?

Kheir, F., Fernandez-Buzzy, S., Gangadharan, S. P. & Majid, A., Feb 1 2019, In : Archivos de bronconeumologia. 55, 2, p. 69-70 2 p.

Research output: Contribution to journalArticle

Tracheobronchomalacia

Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma

Atkinson, A., Renziehausen, A., Wang, H., Lo Nigro, C., Lattanzio, L., Merlano, M., Rao, B., Weir, L., Evans, A., Matin, R., Harwood, C., Szlosarek, P., Pickering, J. G., Fleming, C., Sim, V. R., Li, S., Vasta, J. T., Raines, R. T., Boniol, M., Thompson, A. & 3 othersProby, C., Crook, T. & Syed, N., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Melanoma
Collagen
Growth
Tumors

Combination of different fecal immunochemical tests in colorectal cancer screening: Any gain in diagnostic performance?

Gies, A., Cuk, K., Schrotz-King, P. & Brenner, H., Jan 1 2019, In : Cancers. 11, 1, 120.

Research output: Contribution to journalArticle

Open Access
Early Detection of Cancer
Colorectal Neoplasms
Colonoscopy
Adenoma
Hemoglobins
Kruppel-Like Transcription Factors
Protein-Tyrosine Kinases
Proteolysis
Cell Death
Apoptosis
1 Citation (Scopus)

Combination therapies with HSP90 inhibitors against colorectal cancer

Kryeziu, K., Bruun, J., Guren, T. K., Sveen, A. & Lothe, R., Apr 1 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 2, p. 240-247 8 p.

Research output: Contribution to journalReview article

Open Access
Colorectal Neoplasms
Neoplasms
Oncogenes
Fluorouracil
Immune System
Tumor Microenvironment
Immunotherapy
Melanoma
Clinical Trials
Melanoma-Specific Antigens
9 Citations (Scopus)

Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients with Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial

Massarelli, E., William Jr, W. N., Johnson, F. M., Kies, M. S., Ferrarotto, R., Guo, M., Feng, L., Lee, J-K. J., Tran, H. T., Kim, Y. U., Haymaker, C. L., Bernatchez, C., Curran, M., Zecchini Barrese, T., Rodriguez Canales, J., Wistuba, I. I., Li, L., Wang, J., Van Der Burg, S. H., Melief, C. J. & 1 othersGlisson, B. S., Jan 1 2019, In : JAMA Oncology. 5, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Human papillomavirus 16
Papillomaviridae
Clinical Trials
Neoplasms

Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Camilio, K. A., Wang, M. Y., Mauseth, B., Waagene, S., Kvalheim, G., Rekdal, Ø., Sveinbjørnsson, B. & Mælandsmo, G. M., Jan 22 2019, In : Breast Cancer Research. 21, 1, 9.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Doxorubicin
Carcinogenesis
Peptides
Health
Adenocarcinoma
Therapeutics

Communication about geriatric assessment domains in advanced cancer settings: “Missed opportunities”

Lowenstein, L. M., Volk, R., Street, R., Flannery, M., Magnuson, A., Epstein, R. & Mohile, S. G., Jan 1 2019, In : Journal of Geriatric Oncology. 10, 1, p. 68-73 6 p.

Research output: Contribution to journalArticle

Geriatric Assessment
Communication
Neoplasms
Medical Oncology
Atlases

Comparative analysis of co-occurring mutations of specific tumor suppressor genes in lung adenocarcinoma between Asian and Caucasian populations

Zhang, Y., Ma, Y., Li, Y., Shen, X., Yu, Y., Pan, Y., Zhang, Y., Zheng, D., Zhao, Y., Ye, T., Li, B., Hu, H., Sun, Y., Zhang, Y., Xiang, J. & Chen, H., Mar 13 2019, In : Journal of cancer research and clinical oncology. 145, 3, p. 747-757 11 p.

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Genetic Suppression
Mutation
Population
Survival
Angiography
Tomography
Liver
Cone-Beam Computed Tomography
Artifacts

Comparative Effectiveness of Medication Therapy Management Eligibility Criteria Across Racial/Ethnic Groups

Spivey, C. A., Qiao, Y., Wang, J., Shih, Y-C. T., Wan, J. Y., Dagogo-Jack, S., Cushman, W. C., Hines, L. E. & Chisholm-Burns, M. A., Jan 1 2019, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Medication Therapy Management
Medicare
Ethnic Groups
Patient Protection and Affordable Care Act
Social Change
Anthracyclines
Breast Neoplasms
Drug Therapy
Cyclophosphamide
Carboplatin

Comparative outcomes of myeloablative and reduced-intensity conditioning allogeneic hematopoietic cell transplantation for therapy-related acute myeloid leukemia with prior solid tumor: A report from the acute leukemia working party of the European society for blood and bone marrow transplantation

Lee, C. J., Labopin, M., Beelen, D., Finke, J., Blaise, D., Ganser, A., Itälä-Remes, M., Chevallier, P., Labussière-Wallet, H., Maertens, J., Yakoub-Agha, I., Bourhis, J. H., Mailhol, A., Mohty, M., Savani, B. N. & Nagler, A., Jan 1 2019, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Cell Transplantation
Cell- and Tissue-Based Therapy
Bone Marrow Transplantation
Acute Myeloid Leukemia
Leukemia
1 Citation (Scopus)

Comparing artificial intelligence algorithms to 157 German dermatologists: the melanoma classification benchmark

Brinker, T. J., Hekler, A., Hauschild, A., Berking, C., Schilling, B., Enk, A. H., Haferkamp, S., Karoglan, A., von Kalle, C., Weichenthal, M., Sattler, E., Schadendorf, D., Gaiser, M. R., Klode, J. & Utikal, J. S., Apr 1 2019, In : European Journal of Cancer. 111, p. 30-37 8 p.

Research output: Contribution to journalArticle

Open Access
Benchmarking
Artificial Intelligence
Melanoma
ROC Curve
Sensitivity and Specificity

Comparison between chronic hepatitis B patients with untreated immune-tolerant phase vs. those with virological response by antivirals

Lee, H. W., Kim, S. U., Oidov, B., Park, J. Y., Kim, D. Y., Ahn, S. H., Han, K. H. & Kim, B. K., Dec 1 2019, In : Scientific reports. 9, 1, 2508.

Research output: Contribution to journalArticle

Open Access
Chronic Hepatitis B
Antiviral Agents
Propensity Score
Liver
Virus Diseases
Symptom Assessment
Dyspnea
Chronic Obstructive Pulmonary Disease
Biomedical Research
Comorbidity
Tertiary Care Centers
Software
Weights and Measures
Iodine
Confidence Intervals

Comparison of a new-generation fecal immunochemical test (FIT) with guaiac fecal occult blood test (gFOBT) in detecting colorectal neoplasia among colonoscopy-referral patients

Guimarães, D. P., Fregnani, J. H. T. G., Reis, R. M. V., Taveira, L. N., Scapulatempo, C. N., Matsushita, M., Silva, S. R. M., Oliveira, C. Z., Longatto-Filho, A., Eklund, C., Paloheimo, L., Mauad, E., Suovaniemi, O. & Syrjänen, K., Jan 1 2019, In : Anticancer research. 39, 1, p. 261-269 9 p.

Research output: Contribution to journalArticle

Guaiac
Occult Blood
Prothrombin Time
Hematologic Tests
Colonoscopy

Comparison of body condition score and other minimally invasive biomarkers between dogs with gastric carcinoma and dogs with chronic gastritis

Seim-Wikse, T., Skancke, E., Nødtvedt, A., Jörundsson, E., Grotmol, T., Kristensen, A. T. & Bjørnvad, C. R., Jan 15 2019, In : Journal of the American Veterinary Medical Association. 254, 2, p. 226-235 10 p.

Research output: Contribution to journalArticle

gastritis
Gastritis
carcinoma
body condition
biomarkers
1 Citation (Scopus)

Comparison of different functional prediction scores using a gene-based permutation model for identifying cancer driver genes

Nono, A. D., Chen, K. & Liu, X., Jan 31 2019, In : BMC Medical Genomics. 12, 22.

Research output: Contribution to journalArticle

Neoplasm Genes
Mutation
Genes
Genome
Neoplasms

Comparison of dynamic contrast-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for evaluation of the effects of sorafenib in a rat model of hepatocellular carcinoma

Muñoz, N. M., Minhaj, A. A., Maldonado, K. L., Kingsley, C. V., Cortes, A. C., Taghavi, H., Polak, U., Mitchell, J., Ensor, J. E., Bankson, J. A., Rashid, A. & Avritscher, R., Apr 1 2019, In : Magnetic Resonance Imaging. 57, p. 156-164 9 p.

Research output: Contribution to journalArticle

Magnetic resonance
Rats
Tumors
Hepatocellular Carcinoma
Ultrasonics

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

Blando, J., Sharma, A., Higa, M. G., Zhao, H., Vence, L., Yadav, S. S., Kim, J., Sepulveda, A. M., Sharp, M., Maitra, A., Wargo, J., Tetzlaff, M., Broaddus, R., Katz, M. H., Varadhachary, G. R., Overman, M. J., Wang, H., Yee, C., Bernatchez, C., Iacobuzio-Donahue, C. & 3 othersBasu, S., Allison, J. P. & Sharma, P., Jan 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1692-1697 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Melanoma
Adenocarcinoma
Neoplasms
Therapeutics

Comparison of microwave ablation and radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis

Tan, W., Deng, Q., Lin, S., Wang, Y. & Xu, G-L., Jan 1 2019, (Accepted/In press) In : International Journal of Hyperthermia.

Research output: Contribution to journalArticle

Microwaves
Meta-Analysis
Hepatocellular Carcinoma
Recurrence
Disease-Free Survival
Ovarian Neoplasms
Neoplasms
Drug Therapy
Operative Time
Ambulatory Surgical Procedures

ComPAS: A Bayesian drug combination platform trial design with adaptive shrinkage

Tang, R., Shen, J. & Yuan, Y., Mar 30 2019, In : Statistics in Medicine. 38, 7, p. 1120-1134 15 p.

Research output: Contribution to journalArticle

Drug Combinations
Shrinkage
Drugs
Pharmaceutical Preparations
Design
Dissection
Melanoma
cyhalothrin
Medicare
Costs and Cost Analysis
Lung
Lung Neoplasms
Tomography

Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden

Liang, W. S., Vergilio, J. A., Salhia, B., Huang, H. J., Oki, Y., Garrido-Laguna, I., Park, H., Westin, J. R., Meric-Bernstam, F., Fabrizio, D., Miller, V. A., Stephens, P. J., Fanale, M. A., Ross, J. S. & Janku, F., Feb 1 2019, In : Oncologist. 24, 2, p. 219-228 10 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Mutation
Genes
Plasma Cells
Gene Frequency

Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: A pilot study

Grizzi, F., Fiorino, S., Qehajaj, D., Fornelli, A., Russo, C., De Biase, D., Masetti, M., Mastrangelo, L., Zanello, M., Lombardi, R., Domanico, A., Accogli, E., Tura, A., Mirandola, L., Chiriva-Internati, M., Bresalier, R., Jovine, E., Leandri, P. & Di Tommaso, L., Feb 28 2019, In : Journal of Translational Medicine. 17, 1, 61.

Research output: Contribution to journalArticle

Open Access
Carcinogenesis
Adenocarcinoma
Degradation
Fractal dimension
Fractals

Concept domain validation and item generation for the Treatment-Induced Neuropathy Assessment Scale (TNAS)

Williams, L. A., Garcia-Gonzalez, A., Mendoza, T. R., Haq, S. & Cleeland, C., Mar 1 2019, In : Supportive Care in Cancer. 27, 3, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

Peripheral Nervous System Diseases
oxaliplatin
Therapeutics
Accidental Falls
Interviews
1 Citation (Scopus)

Conceptual framework of middle hepatic vein anatomy as a roadmap for safe right hepatectomy

Ogiso, S., Okuno, M., Shindoh, J., Sakamoto, Y., Mizuno, T., Araki, K., Goumard, C., Nomi, T., Ishii, T., Uemoto, S., Segraves, Y., Tzeng, C-W. D., Lee, J. E., Vauthey, J. N. & Conrad, C., Jan 1 2019, In : HPB. 21, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Hepatic Veins
Hepatectomy
Anatomy
Hemorrhage
Wounds and Injuries

Concomitant CIS on TURBT does not impact oncological outcomes in patients treated with neoadjuvant or induction chemotherapy followed by radical cystectomy

Vasdev, N., Zargar, H., Noël, J. P., Veeratterapillay, R., Fairey, A. S., Mertens, L. S., Dinney, C. P., Mir, M. C., Krabbe, L. M., Cookson, M. S., Jacobsen, N. E., Gandhi, N. M., Griffin, J., Montgomery, J. S., Yu, E. Y., Xylinas, E., Campain, N. J., Kassouf, W., Dall’Era, M. A., Seah, J. A. & 21 othersErcole, C. E., Horenblas, S., Sridhar, S. S., McGrath, J. S., Aning, J., Shariat, S. F., Wright, J. L., Morgan, T. M., Bivalacqua, T. J., North, S., Barocas, D. A., Lotan, Y., Grivas, P., Stephenson, A. J., Shah, J. B., van Rhijn, B. W., Daneshmand, S., Spiess, P. E., Holzbeierlein, J. M., Thorpe, A. & Black, P. C., Jan 23 2019, In : World journal of urology. 37, 1, p. 165-172 8 p.

Research output: Contribution to journalArticle

Induction Chemotherapy
Cystectomy
Carcinoma in Situ
Urinary Bladder Neoplasms
Drug Therapy

Conditional survival of patients with small renal masses undergoing active surveillance

Petros, F. G., Venkatesan, A. M., Kaya, D., Ng, C. S., Fellman, B. M., Karam, J. A., Wood, C. G. & Matin, S., Mar 1 2019, In : BJU International. 123, 3, p. 447-455 9 p.

Research output: Contribution to journalArticle

Kidney
Survival
Nephrectomy
Growth
Neoplasms
2 Citations (Scopus)

Conducting high-quality research in cardiothoracic surgical education: Recommendations from the Thoracic Education Cooperative Group

Antonoff, M. B., Nguyen, S., Nguyen, T. C. & Odell, D. D., Feb 1 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 820-827.e1

Research output: Contribution to journalArticle

Thorax
Education
Research
Ethics
Sample Size
Open Access
Surgical Pathology
Fluorescence Microscopy
Confocal Microscopy
Hematoxylin
Eosine Yellowish-(YS)
3 Citations (Scopus)

Congenital generalized lipodystrophy in Taiwan

Hsu, R. H., Lin, W. D., Chao, M. C., Hsiao, H. P., Wong, S. L., Chiu, P. C., Chu, S. Y., Ke, Y. Y., Lau, B. H., Chien, Y. H., Hwu, W. L., Tsai, F-J., Wang, C. H. & Lee, N. C., Jan 1 2019, In : Journal of the Formosan Medical Association. 118, 1P1, p. 142-147 6 p.

Research output: Contribution to journalArticle

Congenital Generalized Lipodystrophy
Taiwan
Leptin
Genotype
Acanthosis Nigricans
1 Citation (Scopus)

Connexins in cancer: bridging the gap to the clinic

Aasen, T., Leithe, E., Graham, S. V., Kameritsch, P., Mayán, M. D., Mesnil, M., Pogoda, K. & Tabernero, A., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalReview article

Open Access
Connexins
Gap Junctions
Neoplasms
Precision Medicine
Cell Differentiation

Conservative management of cervical cancer: Current status and obstetrical implications

Fokom Domgue, J. & Schmeler, K. M., Feb 1 2019, In : Best Practice and Research: Clinical Obstetrics and Gynaecology. 55, p. 79-92 14 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
Conization
Morbidity
Standard of Care
Hysterectomy

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo

Aryal, N. K., Pant, V., Wasylishen, A., Parker-Thornburg, J., Baseler, L., El-Naggar, A. K., Liu, B., Kalia, A., Lozano, G. & Arur, S., Jan 15 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 3, p. 960-969 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Serine
HEK293 Cells
Caenorhabditis elegans
Pathologic Processes

Construction of confidence intervals for the maximum of the Youden index and the corresponding cutoff point of a continuous biomarker

Bantis, L. E., Nakas, C. T. & Reiser, B., Jan 1 2019, In : Biometrical Journal. 61, 1, p. 138-156 19 p.

Research output: Contribution to journalArticle

Biomarkers
Confidence interval
Normality
Power Transformation
Observational Study