Find Research Outputs

2019

Far-infrared Radiation Improves Motor Dysfunction and Neuropathology in Spinocerebellar Ataxia Type 3 Mice

Liu, S. W., Chang, J. C., Chuang, S. F., Liu, K. H., Cheng, W. L., Chang, H. J., Chang, H. S., Lin, T. T., Hsieh, C-L., Lin, W. Y., Hsieh, M., Kuo, S. J. & Liu, C. S., Feb 1 2019, In : Cerebellum. 18, 1, p. 22-32 11 p.

Research output: Contribution to journalArticle

Machado-Joseph Disease
Radiation
Purkinje Cells
Cerebellar Diseases
Autophagy

Fatigue following radiation therapy in nasopharyngeal cancer survivors: A dosimetric analysis incorporating patient report and observer rating

MD Anderson Head Neck Cancer Symptom Working Group, Apr 1 2019, In : Radiotherapy and Oncology. 133, p. 35-42 8 p.

Research output: Contribution to journalArticle

Nasopharyngeal Neoplasms
Fatigue
Survivors
Radiotherapy
Pituitary Gland

Fatty Acid β-Oxidation-dependent and -independent Responses and Tumor Aggressiveness Acquired Under Mild Hypoxia

Wakui, M., Kawai, K., Mizushima, T., Nishime, C., Serizawa, A., Suemizu, H., Asakura, K., Yamauchi, Y., Hayashida, T., Suematsu, M. & Murata, M., Jan 1 2019, In : Anticancer research. 39, 1, p. 191-200 10 p.

Research output: Contribution to journalArticle

HCT116 Cells
Fatty Acids
Neoplasms
Heme Oxygenase-1
Facilitative Glucose Transport Proteins

Favorable Cardiovascular Health at Young and Middle Ages and Dementia in Older Age-The CHA Study

Vu, T. H. T., Zhao, L., Liu, L., Schiman, C., Lloyd-Jones, D. M., Daviglus, M. L., Liu, K., Garside, D. B., Stamler, J., Fries, J. F., Shih, Y-C. T. & Allen, N. B., Jan 8 2019, In : Journal of the American Heart Association. 8, 1, p. e009730

Research output: Contribution to journalArticle

Dementia
Health
International Classification of Diseases
Blood Pressure
Social Adjustment

Feasibility and acceptance of oral human papillomavirus detection in the dental office: Results from The National Dental Practice-Based Research Network

The National Dental Practice-Based Research Network, Feb 1 2019, In : Journal of the American Dental Association. 150, 2, p. 130-139.e4

Research output: Contribution to journalArticle

Dental Offices
Tooth
Research
Dentistry
Tablets
Fine Needle Biopsy
Surgical Instruments
Registries
Prospective Studies
Breast Neoplasms

Fecal Microbiota Transplantation: Restoring the Injured Microbiome after Allogeneic Hematopoietic Cell Transplantation

DeFilipp, Z., Hohmann, E., Jenq, R. R. & Chen, Y. B., Jan 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 1, p. e17-e22

Research output: Contribution to journalReview article

Microbiota
Cell Transplantation
Clostridium Infections
Clostridium difficile
Graft vs Host Disease
ferulic acid
Cerebral Infarction
B-Cell Lymphoma
Brain Ischemia
Rats

Fetal hemoglobin induction during decitabine treatment of elderly patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: A potential dynamic biomarker of outcome

Stomper, J., Ihorst, G., Suciu, S., Sander, P. N., Becker, H., Wijermans, P. W., Plass, C., Weichenhan, D., Bissé, E., Claus, R. & Lübbert, M., Jan 1 2019, In : Haematologica. 104, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

decitabine
Fetal Hemoglobin
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Biomarkers

FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells

Zhao, M., Zhuo, M. L., Zheng, X., Su, X. & Meric-Bernstam, F., Jan 1 2019, In : Oncotarget. 10, 1, p. 30-44 15 p.

Research output: Contribution to journalArticle

Alternative Splicing
Protein Isoforms
Breast Neoplasms
Cell Migration Assays
Cell Line

FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation

Yan, J., Zhao, Q., Gabrusiewicz, K. R., Kong, L. Y., Xia, X., Wang, J., Ott, M., Xu, J., Davis, R. E., Huo, L., Rao, G., Sun, S-C., Watowich, S. S., Heimberger, A. B. & Li, S., Dec 1 2019, In : Nature communications. 10, 1, 448.

Research output: Contribution to journalArticle

fibrinogen
progressions
Dendritic Cells
Fibrinogen
Tumors

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3

Wang, J., Sanmamed, M. F., Datar, I., Su, T. T., Ji, L., Sun, J., Chen, L., Chen, Y., Zhu, G., Yin, W., Zheng, L., Zhou, T., Badri, T., Yao, S., Zhu, S., Boto, A., Sznol, M., Melero, I., Vignali, D. A. A., Schalper, K. & 1 othersChen, L., Jan 10 2019, In : Cell. 176, 1-2, p. 334-347.e12

Research output: Contribution to journalArticle

T-cells
Fibrinogen
Tumors
Ligands
T-Lymphocytes

Fibrosis-4 index at diagnosis can predict all-cause mortality in patients with rheumatoid arthritis: A retrospective monocentric study

Kim, S. U., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Park, Y. B., Han, K. H. & Lee, S. W., Jan 1 2019, (Accepted/In press) In : Modern Rheumatology.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Fibrosis
Retrospective Studies
Mortality
Blood Sedimentation

Fibrosis-matched outcomes between chronic hepatitis B patients with drug-induced virological response and inactive carriers

Kim, H. S., Baatarkhuu, O., Lee, H. W., Park, J. Y., Kim, D. Y., Ahn, S. H., Song, K., Han, K. H., Kim, B. K. & Kim, S. U., Jan 1 2019, In : Liver International. 39, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Fibrosis
Liver
Pharmaceutical Preparations
Hepatocellular Carcinoma
1 Citations

First-line axitinib versus sorafenib in Asian patients with metastatic renal cell carcinoma: Exploratory subgroup analyses of Phase III data

Sheng, X., Bi, F., Ren, X., Cheng, Y., Wang, J., Rosbrook, B., Jiang, M. & Guo, J., Jan 1 2019, In : Future Oncology. 15, 1, p. 3267-3277 11 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Disease-Free Survival
Diarrhea
Survival Rate
sorafenib
gemcitabine
Adenocarcinoma
Drug Therapy
130-nm albumin-bound paclitaxel
Confidence Intervals
1 Citations

Five-year Long-term Outcomes of Stereotactic Body Radiation Therapy for Operable Versus Medically Inoperable Stage I Non–small-cell Lung Cancer: Analysis by Operability, Fractionation Regimen, Tumor Size, and Tumor Location

Schonewolf, C. A., Heskel, M., Doucette, A., Singhal, S., Frick, M. A., Xanthopoulos, E. P., Corradetti, M. N., Friedberg, J. S., Pechet, T. T., Christodouleas, J. P., Levin, W., Berman, A., Cengel, K. A., Verma, V., Hahn, S., Kucharczuk, J. C., Rengan, R. & Simone, C. B., Jan 1 2019, In : Clinical Lung Cancer. 20, 1, p. e63-e71

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiotherapy
Neoplasms
Survival
Confidence Intervals

FLT3 internal tandem duplication in patients with acute myeloid leukemia is readily detectable in a single next-generation sequencing assay using the pindel algorithm

Kim, B., Kim, S. J., Lee, S. T., Min, Y. & Choi, J. R., Jan 1 2019, In : Annals of Laboratory Medicine. 39, 3, p. 327-329 3 p.

Research output: Contribution to journalLetter

Acute Myeloid Leukemia
Assays

Fluoroscopy and Cone-Beam CT-guided Fixation by Internal Cemented Screw for Pathologic Pelvic Fractures

Roux, C., Tselikas, L., Yevich, S. M., Sandes Solha, R., Hakime, A., Teriitehau, C., Gravel, G., de Baere, T. & Deschamps, F., Feb 1 2019, In : Radiology. 290, 2, p. 418-425 8 p.

Research output: Contribution to journalArticle

Spontaneous Fractures
Cone-Beam Computed Tomography
Fluoroscopy
Opioid Analgesics
Pain

Focal Rosai–Dorfman disease coexisting with lymphoma in the same anatomic site: a localized histiocytic proliferation associated with MAPK/ERK pathway activation

Garces, S., Yin, C. C., Patel, K. P., Khoury, J., Manning, J. T., Li, S., Xu, J., Pina-Oviedo, S., Johnson, M. R., González, S., Molgó, M., Ruiz-Cordero, R. & Medeiros, L. J., Jan 1 2019, In : Modern Pathology. 32, 1, p. 16-26 11 p.

Research output: Contribution to journalArticle

Sinus Histiocytosis
MAP Kinase Signaling System
Lymphoma
Histiocytes
Hodgkin Disease

Focal therapy for localized prostate cancer: Is there a 'middle ground' between active surveillance and definitive treatment?

Demirel, C. H., Altok, M. & Davis, J. W., Jan 1 2019, In : Asian Journal of Andrology. 21, 1, p. 37-44 8 p.

Research output: Contribution to journalReview article

Prostatic Neoplasms
Therapeutics
Publications
Prostate
Research

FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase

Son, D. H., Doan, K. V., Yang, D. J., Sun, J. S., Kim, S. K., Kang, N., Kang, J. Y., Paik, J. H., DePinho, R. A., Choi, Y. H., Shin, D. M. & Kim, K. W., Feb 1 2019, In : Metabolism: clinical and experimental. 91, p. 43-52 10 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Leptin
STAT3 Transcription Factor
Dopaminergic Neurons
Anti-Anxiety Agents

Frailty, transition in frailty status and all-cause mortality in older adults of a Taichung community-based population

Wang, M. C., Li, T-C., Li, C. I., Liu, C. S., Lin, W-Y., Lin, C-H., Yang, C. W., Yang, S. Y. & Lin, C-C., Jan 28 2019, In : BMC Geriatrics. 19, 1, 26.

Research output: Contribution to journalArticle

Frequency and clinical significance of NF1 mutation in lung adenocarcinomas from East Asian patients

Pan, Y., Yuan, C., Cheng, C., Zhang, Y., Ma, Y., Zheng, D., Zheng, S., Li, Y., Jin, Y., Sun, Y. & Chen, H., Jan 15 2019, In : International Journal of Cancer. 144, 2, p. 290-296 7 p.

Research output: Contribution to journalArticle

Mutation
Adenocarcinoma of lung
Disease-Free Survival
Semiconductors
Survival

Fully Automatic Treatment Planning for External-Beam Radiation Therapy of Locally Advanced Cervical Cancer: A Tool for Low-Resource Clinics

Kisling, K., Zhang, L., Simonds, H., Fakie, N., Yang, J., McCarroll, R., Balter, P. A., Burger, H., Bogler, O., Howell, R. M., Schmeler, K. M., Mejia, M., Beadle, B. M., Jhingran, A. & Court, L. E., Jan 1 2019, In : Journal of global oncology. 2019, p. 1-9 9 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Radiotherapy
South Africa
Therapeutics
Tomography

Functional Proteomics of Breast Cancer Metabolism Identifies GLUL as Responder during Hypoxic Adaptation

Bernhardt, S., Tönsing, C., Mitra, D., Erdem, N., Müller-Decker, K., Korf, U., Kreutz, C., Timmer, J. & Wiemann, S., Jan 1 2019, (Accepted/In press) In : Journal of Proteome Research.

Research output: Contribution to journalArticle

Function and Strength after Free Abdominally Based Breast Reconstruction: A 10-Year Follow-Up

Nelson, J. A., Tecci, M. G., Lanni, M. A., Fischer, J. P., Fosnot, J., Selber, J. C., Wu, L. C. & Serletti, J. M., Jan 1 2019, In : Plastic and reconstructive surgery. 143, 1, p. 22e-31e

Research output: Contribution to journalArticle

Mammaplasty
antineoplaston A10
Mental Health
Diagnostic Self Evaluation
Obesity

Functions and clinical implications of exosomes in pancreatic cancer

Qian, L., Yu, S., Chen, Z., Meng, Z., Huang, S. & Wang, P., Jan 1 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 1, p. 75-84 10 p.

Research output: Contribution to journalReview article

Exosomes
Pancreatic Neoplasms
Immune Evasion
Drug Resistance
Neoplasms

Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal caner

Zhang, S., Yang, Y., Weng, W., Guo, B., Cai, G., Ma, Y. & Cai, S., Jan 10 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 14.

Research output: Contribution to journalArticle

Fusobacterium nucleatum
Fusobacterium Infections
Fluorouracil
Up-Regulation
Colorectal Neoplasms

GADD45A binds R-loops and recruits TET1 to CpG island promoters

Arab, K., Karaulanov, E., Musheev, M., Trnka, P., Schäfer, A., Grummt, I. & Niehrs, C., Feb 1 2019, In : Nature Genetics. 51, 2, p. 217-223 7 p.

Research output: Contribution to journalLetter

CpG Islands
DNA Damage
DNA
Growth
Antisense RNA
1 Citations

Galectins as regulators of cell survival in the leukemia niche

Ruvolo, P., Jan 1 2019, In : Advances in Biological Regulation. 71, p. 41-54 14 p.

Research output: Contribution to journalReview article

Galectin 1
Galectins
Galectin 3
Cell Survival
Leukemia
Paneth Cells
Esophagogastric Junction
Carcinoma
beta Catenin
Coloring Agents
2 Citations

gBOIN: a unified model-assisted phase I trial design accounting for toxicity grades, and binary or continuous end points

Mu, R., Yuan, Y., Xu, J., Mandrekar, S. J. & Yin, J., Feb 1 2019, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 68, 2, p. 289-308 20 p.

Research output: Contribution to journalArticle

Phase I Trial
End point
Toxicity
Dose
Binary

Gene expression profiles analysis identifies a novel two-gene signature to predict overall survival in diffuse large B-cell lymphoma

Sun, C., Cheng, X., Wang, C., Wang, X., Xia, B. & Zhang, Y., Jan 3 2019, In : Bioscience reports. 39, 1, BSR20181293.

Research output: Contribution to journalArticle

prostaglandin R2 D-isomerase
Lymphoma, Large B-Cell, Diffuse
Transcriptome
Gene expression
Genes
Binge Drinking
Psychology
Impulsive Behavior
Hispanic Americans
Social Support
1 Citations
Prostatic Neoplasms
Single Nucleotide Polymorphism
T-Lymphocytes
Neoplasm Grading
Neoplasms

Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population

Imaizumi, A., Adachi, Y., Kawaguchi, T., Higasa, K., Tabara, Y., Sonomura, K., Sato, T. A., Takahashi, M., Mizukoshi, T., Yoshida, H. O., Kageyama, N., Okamoto, C., Takasu, M., Mori, M., Noguchi, Y., Shimba, N., Miyano, H., Yamada, R. & Matsuda, F., Jan 1 2019, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Amino Acids
Population
Quantitative Trait Loci
Glycine

Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident

Fisher, S. B., Cote, G., Bui-Griffith, J. H., Lu, W., Tang, X., Hai, T., Fisher, K. E., Williams, M. D., Wistuba, I. I., Waguespack, S. G., Dorman, C. M., Ludwig, M. S., Graham, P. H., Perrier, N. D., Lee, J. E. & Grubbs, E. G., Jan 1 2019, In : Surgery (United States). 165, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

Accidents
Survivors
Germ-Line Mutation
Radiation
Oncogene Fusion
2 Citations

Genetic Factors That Affect Spontaneous Clearance of Hepatitis C or B Virus, Response to Treatment, and Disease Progression

O'Brien, T. R., Yang, H-I., Groover, S. & Jeng, W. J., Jan 1 2019, In : Gastroenterology. 156, 2, p. 400-417 18 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepacivirus
Disease Progression
Virus Diseases
End Stage Liver Disease

Genetic variation associated with chromosomal aberration frequency: A genome-wide association study

Niazi, Y., Thomsen, H., Smolkova, B., Vodickova, L., Vodenkova, S., Kroupa, M., Vymetalkova, V., Kazimirova, A., Barancokova, M., Volkovova, K., Staruchova, M., Hoffmann, P., Nöthen, M. M., Dušinská, M., Musak, L., Vodicka, P., Hemminki, K. & Försti, A., Jan 1 2019, In : Environmental and Molecular Mutagenesis. 60, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Chromosome Aberrations
Neoplasms
Smoking
M Phase Cell Cycle Checkpoints

Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL-60 cancer cell xenograft growth in vivo

Hsiao, Y. C., Peng, S. F., Lai, K. C., Liao, C. L., Huang, Y. P., Lin, C. C., Lin, M. L., Liu, K. C., Tsai, C. C., Ma, Y. S. & Chung, J-G., Jan 1 2019, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Genistein
HL-60 Cells
apoptosis
Heterografts
Human Activities
Uniparental Disomy
Smoking
Alleles
Alcohols
Genome

Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection

Takeuchi, F., Kukimoto, I., Li, Z., Li, S., Li, N., Hu, Z., Takahashi, A., Inoue, S., Yokoi, S., Chen, J., Hang, D., Kuroda, M., Matsuda, F., Mizuno, M., Mori, S., Wu, P., Tanaka, N., Matsuo, K., Kamatani, Y., Kubo, M. & 2 othersMa, D. & Shi, Y., Jan 15 2019, In : Human molecular genetics. 28, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

Arrestin
Papillomavirus Infections
Genome-Wide Association Study
Uterine Cervical Neoplasms
Single Nucleotide Polymorphism

Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier)

Gündert, M., Edelmann, D., Benner, A., Jansen, L., Jia, M., Walter, V., Knebel, P., Herpel, E., Chang-Claude, J., Hoffmeister, M., Brenner, H. & Burwinkel, B., Jan 1 2019, In : Gut. 68, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Colorectal Neoplasms
Genome
Survival
Methylation

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

Ko, T. M., Chang, J. S., Chen, S. P., Liu, Y. M., Chang, C. J., Tsai, F-J., Lee, Y. C., Chen, C. H., Chen, Y. T. & Wu, J. Y., Dec 1 2019, In : Scientific reports. 9, 1, 328.

Research output: Contribution to journalArticle

Long Noncoding RNA
Neutrophil Activation
Mucocutaneous Lymph Node Syndrome
Gene Expression Profiling
Genome
1 Citations

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy

Berlin, A., Murgic, J., Hosni, A., Pintilie, M., Salcedo, A., Fraser, M., Kamel-Reid, S., Zhang, J., Wang, Q., Ch'ng, C., Deheshi, S., Davicioni, E., van der Kwast, T., Boutros, P. C., Bristow, R. G. & Chua, M. L. K., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics. 103, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

Image-Guided Radiotherapy
hormones
classifiers
radiation therapy
therapy
1 Citations

German Cancer Consortium (DKTK) – A national consortium for translational cancer research

Joos, S., Nettelbeck, D. M., Reil-Held, A., Engelmann, K., Moosmann, A., Eggert, A., Hiddemann, W., Krause, M., Peters, C., Schuler, M., Schulze-Osthoff, K., Serve, H., Wick, W., Puchta, J. & Baumann, M., Jan 1 2019, (Accepted/In press) In : Molecular oncology.

Research output: Contribution to journalArticle

Translational Medical Research
Neoplasms
Germany
Research
Peer Review
2 Citations

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

Yurgelun, M. B., Chittenden, A. B., Morales-Oyarvide, V., Rubinson, D. A., Dunne, R. F., Kozak, M. M., Qian, Z. R., Welch, M. W., Brais, L. K., Da Silva, A., Bui, J. L., Yuan, C., Li, T., Li, W., Masuda, A., Gu, M., Bullock, A. J., Chang, D. T., Clancy, T. E., Linehan, D. C. & 18 othersFindeis-Hosey, J. J., Doyle, L. A., Thorner, A. R., Ducar, M. D., Wollison, B. M., Khalaf, N., Perez, K., Syngal, S., Aguirre, A. J., Hahn, W. C., Meyerson, M. L., Fuchs, C. S., Ogino, S., Hornick, J. L., Hezel, A. F., Koong, A., Nowak, J. A. & Wolpin, B. M., Jan 1 2019, In : Genetics in Medicine. 21, 1, p. 213-223 11 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Pancreatic Neoplasms
DNA Repair
DNA Damage
Adenocarcinoma

GHSR DNA hypermethylation is a new epigenetic biomarker for gastric adenocarcinoma and beyond

Amini, M., Foroughi, K., Talebi, F., Aghagolzade Haji, H., Kamali, F., Jandaghi, P., Hoheisel, J. & Manoochehri, M., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Gigantol has protective effects against high glucose-evoked nephrotoxicity in mouse glomerulus mesangial cells by suppressing ROS/MAPK/NF-κB signaling pathways

Chen, M. F., Liou, S. S., Hong, T. Y., Kao, S. T. & Liu, I. M., Jan 1 2019, In : Molecules. 24, 1, 80.

Research output: Contribution to journalArticle

glomerulus
Mesangial Cells
Mitogen-Activated Protein Kinases
glucose
mice