Find Research Outputs

2019
Open Access
Advanced Glycosylation End Products
Muscle Strength
Bone Density
Skeletal Muscle
Odds Ratio

Advanced hepatocellular carcinoma with bone metastases: Prevalence, associated factors, and survival estimation

Guo, X., Xu, Y., Wang, X., Lin, F., Wu, H., Duan, J., Xiong, Y., Han, X., Baklaushev, V. P., Xiong, S., Chekhonin, V. P., Peltzer, K., Wang, G. & Zhang, C., Jan 1 2019, In : Medical Science Monitor. 25, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasm Metastasis
Bone and Bones
Survival
Marital Status
1 Citation (Scopus)

Advanced stage breast cancer is associated with catheter-tip thrombus formation following implantable central venous port placement

Makary, M. S., Lionberg, A., Khayat, M., Lustberg, M. B., AlTaani, J., Pan, X. J., Layman, R. R., Raman, S. V., Layman, R. M. & Dowell, J. D., Mar 1 2019, In : Phlebology. 34, 2, p. 107-114 8 p.

Research output: Contribution to journalArticle

Thrombosis
Catheters
Breast Neoplasms
Thorax
Jugular Veins
2 Citations (Scopus)

Advances in Auto-Segmentation

Cardenas, C. E., Yang, J., Anderson, B. M., Court, L. E. & Brock, K. B., Jul 1 2019, In : Seminars in radiation oncology. 29, 3, p. 185-197 13 p.

Research output: Contribution to journalReview article

Radiotherapy
Learning
Observer Variation
Software
Safety

Advances in Biomaterials and Technologies for Vascular Embolization

Hu, J., Albadawi, H., Chong, B. W., Deipolyi, A. R., Sheth, R. A., Khademhosseini, A. & Oklu, R., Jan 1 2019, In : Advanced Materials. 31, 33, 1901071.

Research output: Contribution to journalReview article

Biocompatible Materials
Biomaterials
Biodegradable polymers
Radiology
Blood vessels

Advances in hematopoietic stem cell transplantation in the Asia-Pacific region: the second report from APBMT 2005–2015

Registry Committee of the Asia-Pacific Blood and Marrow Transplantation Group (APBMT), Jan 1 2019, In : Bone marrow transplantation.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
China
Hemoglobinopathies
Vietnam
Pakistan
5 Citations (Scopus)

Advances in HER2-targeted therapy: Novel agents and opportunities beyond breast and gastric cancer

Meric-Bernstam, F., Johnson, A. M., Ileana Dumbrava, E. E., Raghav, K. P. S., Balaji, K., Bhatt, M., Murthy, R. K., Rodon Ahnert, J. & Piha-Paul, S. A., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2033-2041 9 p.

Research output: Contribution to journalReview article

Stomach Neoplasms
Breast Neoplasms
Therapeutics
Biliary Tract Neoplasms
Neoplasms
1 Citation (Scopus)

Advances in multidisciplinary therapy for meningiomas

International Consortium on Meningiomas, Jan 14 2019, In : Neuro-oncology. 21, p. I18-I31

Research output: Contribution to journalArticle

Open Access
Meningioma
trabectedin
Therapeutics
Radiotherapy
Focal Adhesion Protein-Tyrosine Kinases
1 Citation (Scopus)

Advances in patient care through increasingly individualized therapy

DiNardo, C. & Perl, A. E., Feb 1 2019, In : Nature Reviews Clinical Oncology. 16, 2, p. 73-74 2 p.

Research output: Contribution to journalArticle

Patient Care
Acute Myeloid Leukemia
Therapeutics
Gene Expression
Mutation

Advances in PET Imaging of Sarcoidosis

Lu, Y. & Macapinlac, H. A., Mar 1 2019, In : Current Cardiovascular Imaging Reports. 12, 3, 10.

Research output: Contribution to journalReview article

Sarcoidosis
Positron-Emission Tomography
Perfusion
Carbohydrate-Restricted Diet
Fluorodeoxyglucose F18

Advances in technologies for cervical cancer detection in low-resource settings

Kundrod, K. A., Smith, C. A., Hunt, B., Schwarz, R. A., Schmeler, K. M. & Richards-Kortum, R., Jan 1 2019, In : Expert Review of Molecular Diagnostics. 19, 8, p. 695-714 20 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
Technology
Early Detection of Cancer
Medically Underserved Area
Molecular Imaging

Advances in the diagnosis and surveillance of Barrett's esophagus (with videos)

The ASGE Technology Committee, Sep 1 2019, In : Gastrointestinal endoscopy. 90, 3, p. 325-334 10 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Technology
Biomarkers
Adenocarcinoma
Fluorescence In Situ Hybridization
Chelating Agents
Catheters
Infection
Catheter-Related Infections
Anti-Infective Agents

Advances in treatment of synovial sarcoma

Tao, F., Han, X., Wang, G., Zhang, C. & Li, L., Apr 1 2019, In : Tumor. 39, 4, p. 317-324 8 p., 1000-7431 (2019) 04-0317-08.

Research output: Contribution to journalArticle

Synovial Sarcoma
Therapeutics
trabectedin
Drug Therapy
Sarcoma
1 Citation (Scopus)

Advancing drug development in gynecologic malignancies

Beaver, J. A., Coleman, R., Arend, R. C., Armstrong, D. K., Bala, S., Mills, G. B., Sood, A. K. & Herzog, T. J., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4874-4880 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Pharmaceutical Preparations
Neoplasms
Drug Approval
Education

Adverse effect of lymph node dissection in metastatic renal cell cancer patients treated with cytoreductive nephrectomy: A contemporary analysis of survival

Cao, D., Huang, Y., Zhang, C., Wu, J., Yu, L., Zhang, H., Shi, G. & Ye, D., Jan 1 2019, In : Journal of Cancer. 10, 19, p. 4639-4646 8 p.

Research output: Contribution to journalArticle

Open Access
Survival Analysis
Lymph Node Excision
Nephrectomy
Renal Cell Carcinoma
Survival
8 Citations (Scopus)

Adverse Effects of Immune Checkpoint Therapy in Cancer Patients Visiting the Emergency Department of a Comprehensive Cancer Center

El Majzoub, I., Qdaisat, A., Thein, K. Z., Win, M. A., Han, M. M., Jacobson, K., Chaftari, P., Prejean, M., Reyes-Gibby, C. C. & Yeung, S. J., Jan 1 2019, In : Annals of Emergency Medicine. 73, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

Hospital Emergency Service
Neoplasms
Diarrhea
Therapeutics
Thyroiditis
Open Access
Hypogonadism
Testicular Neoplasms
Multicenter Studies
Survivors
Drug Therapy

A feasible CT feature to differentiate focal-type autoimmune pancreatitis from pancreatic ductal adenocarcinoma

He, C., Rong, D., Hu, W., Cai, Q., Yang, Q., Mao, Y., Zhang, R., Li, S-P. & Lv, Y., Jan 1 2019, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journalArticle

Open Access
Pancreatitis
Adenocarcinoma
Tomography
ROC Curve
Nuclear Family
4 Citations (Scopus)

A first-in-human study and biomarker analysis of NKTR-214, a novel IL2Rβγ-biased cytokine, in patients with advanced or metastatic solid tumors

Bentebibel, S. E., Hurwitz, M. E., Bernatchez, C., Haymaker, C. L., Hudgens, C. W., Kluger, H. M., Tetzlaff, M., Tagliaferri, M. A., Zalevsky, J., Hoch, U., Fanton, C., Aung, S., Hwu, P., Curti, B. D., Tannir, N. M., Sznol, M. & Diab, A., Jun 1 2019, In : Cancer discovery. 9, 6, p. 711-721 11 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-2
Biomarkers
Interleukin-2 Receptors
Cytokines
Biopsy

A flexible and robust method for assessing conditional association and conditional concordance

Liu, X., Ning, J., Cheng, Y., Huang, X. & Li, R., Jan 1 2019, In : Statistics in Medicine.

Research output: Contribution to journalArticle

Concordance
Robust Methods
Covariates
Association Measure
Kendall's tau

AFM to study pore-forming proteins

Unsay, J. D. & Garcia-Saez, A., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 191-202 12 p. (Methods in Molecular Biology; vol. 1886).

Research output: Chapter in Book/Report/Conference proceedingChapter

Porins
Atomic Force Microscopy
Membranes
Lipid Bilayers
Microscopy
1 Citation (Scopus)

A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma

Wang, Y., Ruan, Z., Yu, S., Tian, T., Liang, X., Jing, L., Li, W., Wang, X., Xiang, L. C. L., Claret, F-X., Nan, K. & Guo, H., Jan 1 2019, In : Aging. 11, 1, p. 160-173 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Messenger RNA
Survival
Nomograms
BRCA1 Gene

A Framework to Prioritise Health Research Proposals for Funding: Integrating Value for Money

Tuffaha, H., Aitken, J., Chambers, S. & Scuffham, P. A., Jan 1 2019, In : Applied Health Economics and Health Policy.

Research output: Contribution to journalArticle

Research Design
Health
Research
Value for money
Funding

A functional model for classifying metastatic lesions integrating scans and biomarkers

Wang, Y., Hu, J., Ng, C. S. & Hobbs, B. P., Jan 1 2019, In : Statistical Methods in Medical Research.

Research output: Contribution to journalArticle

Functional Model
Biomarkers
Perfusion
Computed Tomography
Liver

Age-Associated Risk of 90-Day Postoperative Mortality after Cytoreductive Surgery for Advanced Ovarian Cancer

Melamed, A., Bercow, A. S., Bunnell, K., Rauh-Hain, J. A., Wright, J. D., Rice, L. W. & Del Carmen, M. G., Jul 1 2019, In : JAMA Surgery. 154, 7, p. 669-671 3 p.

Research output: Contribution to journalLetter

Ovarian Neoplasms
Mortality

Age at menarche and epithelial ovarian cancer risk: A meta-analysis and Mendelian randomization study

Yang, H., Dai, H., Li, L., Wang, X., Wang, P., Song, F., Zhang, B. & Chen, K., Jul 1 2019, In : Cancer medicine. 8, 8, p. 4012-4022 11 p.

Research output: Contribution to journalArticle

Open Access
Menarche
Random Allocation
Mendelian Randomization Analysis
Ovarian Neoplasms
Meta-Analysis
1 Citation (Scopus)

A Generic Sure Independence Screening Procedure

Pan, W., Wang, X., Xiao, W. & Zhu, H., Apr 3 2019, In : Journal of the American Statistical Association. 114, 526, p. 928-937 10 p.

Research output: Contribution to journalArticle

Screening
Medicine
Statistical Learning
Pursuit
High-dimensional Data

A genome-wide association study of prostate cancer in Latinos

Du, Z., Hopp, H., Ingles, S. A., Huff, C., Sheng, X., Weaver, B., Stern, M., Hoffmann, T. J., John, E. M., Van Den Eeden, S. K., Strom, S., Leach, R. J., Thompson, I. M., Witte, J. S., Conti, D. V. & Haiman, C. A., Jan 1 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Hispanic Americans
Prostatic Neoplasms
Population
Genome
1 Citation (Scopus)

Age-specific health-related quality of life in long-term and very long-term colorectal cancer survivors versus population controls–a population-based study*

Thong, M. S. Y., Koch-Gallenkamp, L., Jansen, L., Bertram, H., Eberle, A., Holleczek, B., Waldeyer-Sauerland, M., Waldmann, A., Zeissig, S. R., Brenner, H. & Arndt, V., May 4 2019, In : Acta Oncologica. 58, 5, p. 801-810 10 p.

Research output: Contribution to journalArticle

Survivors
Colorectal Neoplasms
Quality of Life
Population
Population Control

A giant leap for womankind

Valantine, H., Travis, E. L., El-Adhami, W., Vernos, I., Mosqueda, L., Wayne, E., Kearns-Zimmerman, F., Bonefont, L., Visweswariah, S. S., Akande-Sholabi, W. & Polka, J., May 1 2019, In : Nature medicine. 25, 5, p. 704-707 4 p.

Research output: Contribution to journalComment/debate

Aging and the cancer burden in Latin America and the Caribbean: Time to act

Pilleron, S., Soerjomataram, I., Soto-Perez-de-Celis, E., Ferlay, J., Vega, E., Bray, F. I. & Piñeros, M., Sep 1 2019, In : Journal of Geriatric Oncology. 10, 5, p. 799-804 6 p.

Research output: Contribution to journalArticle

Latin America
Neoplasms
Central America
South America
Skin Neoplasms
2 Citations (Scopus)

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Chiu Yen, R. W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C. A., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journalArticle

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

A global immune gene expression signature for human cancers

Liu, Y., Mar 1 2019, In : Oncotarget. 10, 20, p. 1993-2005 13 p.

Research output: Contribution to journalArticle

Transcriptome
Neoplasms
Genes
Transcription Factors
Th2 Cells

A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV)

Warren, C. J., Meyerson, N. R., Stabell, A. C., Fattor, W. T., Wilkerson, G. K. & Sawyer, S. L., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11460-11469 10 p.

Research output: Contribution to journalArticle

Primate Lentiviruses
Pan troglodytes
Polysaccharides
HIV
Infection
Open Access
Acceptance and Commitment Therapy
Internet
Waiting Lists
Survivors
Breast Neoplasms
1 Citation (Scopus)

A GYS2/p53 negative feedback loop restricts tumor growth in HBV-related hepatocellular carcinoma

Chen, S. L., Zhang, C. Z., Liu, L. L., Lu, S. X., Pan, Y. H., Wang, C. H., He, Y. F., Lin, C. S., Yang, X., Xie, D. & Yun, J-P., Feb 1 2019, In : Cancer research. 79, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Hepatocellular Carcinoma
Growth
Neoplasms
Glycogen
23 Citations (Scopus)

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

Walker, B. A., Mavrommatis, K., Wardell, C. P., Ashby, T. C., Bauer, M., Davies, F., Rosenthal, A., Wang, H., Qu, P., Hoering, A., Samur, M., Towfic, F., Ortiz, M., Flynt, E., Yu, Z., Yang, Z., Rozelle, D., Obenauer, J., Trotter, M., Auclair, D. & 19 others, Keats, J., Bolli, N., Fulciniti, M., Szalat, R., Moreau, P., Durie, B., Stewart, A. K., Goldschmidt, H., Raab, M-S., Einsele, H., Sonneveld, P., San Miguel, J., Lonial, S., Jackson, G. H., Anderson, K. C., Avet-Loiseau, H., Munshi, N., Thakurta, A. & Morgan, G., Jan 1 2019, In : Leukemia. 33, 1, p. 159-170 12 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Multiple Myeloma
Survival
Genome
Exome

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy

Tiessen, I., Abildgaard, M. H., Lubas, M., Gylling, H. M., Steinhauer, C., Pietras, E. J., Diederichs, S., Frankel, L. B. & Lund, A. H., Jun 27 2019, In : Oncogene. 38, 26, p. 5127-5141 15 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Autophagy
Untranslated RNA
MCF-7 Cells
Eukaryotic Cells

A homogenized approach to classify advanced gastric cancer patients with limited and adequate number of pathologically examined lymph nodes

Seeruttun, S. R., Xu, L., Wang, F., Yi, X., Fang, C., Liu, Z., Wang, W. & Zhou, Z-W., Jun 10 2019, In : Cancer Communications. 39, 1, 32.

Research output: Contribution to journalArticle

Open Access
Stomach Neoplasms
Lymph Nodes
Neoplasm Metastasis
Neoplasms
Survival Rate

A hybrid phase I-II/III clinical trial design allowing dose re-optimization in phase III

Chapple, A. G. & Thall, P. F., Jan 1 2019, In : Biometrics. 75, 2, p. 371-381 11 p.

Research output: Contribution to journalArticle

Reoptimization
Clinical Trials
clinical trials
Dose
Toxicity

AIDS-related Kaposi sarcoma, version 2.2019

Reid, E., Suneja, G., Ambinder, R. F., Ard, K., Baiocchi, R., Barta, S. K., Carchman, E., Cohen, A., Crysler, O. V., Gupta, N., Gustafson, C., Hall, A., Johung, K. L., Klopp, A. H., LaCasce, A. S., Lin, C., Mehta, A., Menon, M. P., Morgan, D., Nathwani, N. & 11 others, Noy, A., Ratner, L., Rizza, S., Rudek, M. A., Sanchez, J., Taylor, J., Tomlinson, B., Wang, C. C. J., Yendamuri, S., Dwyer, M. A. & Freedman-Cass, D. A., Feb 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 2, p. 171-189 19 p.

Research output: Contribution to journalArticle

Open Access
Kaposi's Sarcoma
HIV
Acquired Immunodeficiency Syndrome
Skin
Practice Guidelines

Airborne particulate matter induces mitotic slippage and chromosomal missegregation through disruption of the spindle assembly checkpoint (SAC)

Santibáñez-Andrade, M., Sánchez-Pérez, Y., Chirino, Y. I., Morales-Bárcenas, R., Herrera, L. A. & Garcia-Cuellar, C., Nov 1 2019, In : Chemosphere. 235, p. 794-804 11 p.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Particulate Matter
particulate matter
protein
Proteins

Air pollutants are associated with obstructive sleep apnea severity in non-rapid eye movement sleep

Cheng, W. J., Liang, S. J., Huang, C. S., Lin, C. L., Pien, L. C. & Hang, L-W., Jan 1 2019, In : Journal of Clinical Sleep Medicine. 15, 6, p. 831-837 7 p.

Research output: Contribution to journalArticle

Air Pollutants
Obstructive Sleep Apnea
Apnea
Eye Movements
Sleep

AJCC 7th edition staging classification is more applicable than AJCC 8th edition staging classification for invasive IPMN

Fan, Z., Cheng, H., Jin, K., Gong, Y., Huang, Q., Xu, J., Ni, Q., Yu, X., Liu, C. & Luo, G., Aug 6 2019, In : World journal of surgical oncology. 17, 1, 137.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Neoplasm Staging
Survival Analysis
Registries
Pancreas

AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway

Cui, Y., Wu, X., Lin, C., Zhang, X., Ye, L., Ren, L., Chen, M., Yang, M., Li, Y., Li, M., Li, J., Guan, J. & Song, L-B., Jul 4 2019, In : Oncogene. 38, 27, p. 5516-5529 14 p.

Research output: Contribution to journalArticle

Catenins
Hepatocellular Carcinoma
Recurrence
Adenomatous Polyposis Coli Protein
Cyclic AMP Response Element-Binding Protein

AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis

Kircher, D. A., Trombetti, K. A., Silvis, M. R., Parkman, G. L., Fischer, G. M., Angel, S. N., Stehn, C. M., Strain, S. C., Grossmann, A. H., Duffy, K. L., Boucher, K. M., McMahon, M., Davies, M. A., Mendoza, M. C., VanBrocklin, M. W. & Holmen, S. L., Sep 1 2019, In : Molecular cancer research : MCR. 17, 9, p. 1787-1800 14 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Melanoma
Neoplasm Metastasis
Brain
Mutation
1 Citation (Scopus)

Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study

Brenner, D. R., Fehringer, G., Zhang, Z. F., Lee, Y. C. A., Meyers, T., Matsuo, K., Ito, H., Vineis, P., Stucker, I., Boffetta, P., Brennan, P., Christiani, D. C., Diao, N., Hong, Y. C., Landi, M. T., Morgenstern, H., Schwartz, A. G., Rennert, G., Saliba, W., McLaughlin, J. R. & 19 others, Harris, C. C., Orlow, I., Barros Dios, J. M., Ruano Raviña, A., Siemiatycki, J., Koushik, A., Cote, M., Lazarus, P., Fernandez-Tardon, G., Tardon, A., Le Marchand, L., Brenner, H., Saum, K. U., Duell, E. J., Andrew, A. S., Consonni, D., Olsson, A., Hung, R. J. & Straif, K., Feb 1 2019, In : Cancer Epidemiology. 58, p. 25-32 8 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Lung Neoplasms
Squamous Cell Carcinoma
Alcoholic Beverages
Odds Ratio
4 Citations (Scopus)

Alisertib in Combination with Weekly Paclitaxel in Patients with Advanced Breast Cancer or Recurrent Ovarian Cancer: A Randomized Clinical Trial

Falchook, G., Coleman, R., Roszak, A., Behbakht, K., Matulonis, U., Ray-Coquard, I., Sawrycki, P., Duska, L. R., Tew, W., Ghamande, S., Lesoin, A., Schwartz, P. E., Buscema, J., Fabbro, M., Lortholary, A., Goff, B., Kurzrock, R., Martin, L. P., Gray, H. J., Fu, S. & 6 others, Sheldon-Waniga, E., Lin, H. M., Venkatakrishnan, K., Zhou, X., Leonard, E. J. & Schilder, R. J., Jan 1 2019, In : JAMA Oncology. 5, 1

Research output: Contribution to journalArticle

Paclitaxel
Ovarian Neoplasms
Randomized Controlled Trials
Breast Neoplasms
Disease-Free Survival

ALKATI interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma

Xu, B. S., Chen, H. Y., Que, Y., Xiao, W., Zeng, M-S. & Zhang, X., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Sarcoma
Stem Cells
Cell Nucleus
Disease-Free Survival