Find Research Outputs

Search concepts
Selected Filters
2020

A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis

Umu, S. U., Langseth, H., Keller, A., Meese, E., Helland, Å., Lyle, R. & Rounge, T. B., Feb 1 2020, In : Molecular oncology. 14, 2, p. 235-247 13 p.

Research output: Contribution to journalArticle

Open Access
Lung Neoplasms
Carcinogenesis
RNA
Lung
Serum
Fallopian Tubes
Carcinoma
Drug Therapy
Disease-Free Survival
Omentum

Acute myeloid leukemia with a novel CPSF6-RARG variant is sensitive to homoharringtonine and cytarabine chemotherapy

Zhang, Z., Jiang, M., Borthakur, G., Luan, S., Huang, X., Tang, G., Xu, Q., Ji, D., Boyer, A. D., Li, F., Huang, R. & You, M. J., Feb 1 2020, In : American journal of hematology. 95, 2, p. E48-E51

Research output: Contribution to journalLetter

Open Access

Acute respiratory failure and the kinetics of neutrophil recovery in pediatric hematopoietic cell transplantation: a multicenter study

Investigators of the Pediatric Acute Lung Injury and Sepsis Network, Feb 1 2020, In : Bone marrow transplantation.

Research output: Contribution to journalArticle

Cell Transplantation
Artificial Respiration
Respiratory Insufficiency
Multicenter Studies
Neutrophils

Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

Zhu, Q., Zhong, A. L., Hu, H., Zhao, J. J., Weng, D. S., Tang, Y., Pan, Q. Z., Zhou, Z. Q., Song, M. J., Yang, J. Y., He, J. Y., Liu, Y., Li, M., Hu, W. M., Yang, C. P., Xiang, T., Chen, M. Y., Ma, G., Guo, L. & Xia, J. C., Jan 3 2020, In : Journal of hematology & oncology. 13, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
acylglycerol kinase
Phosphatidylinositol 3-Kinases
Renal Cell Carcinoma
Neoplasm Metastasis
Growth
1 Citation (Scopus)
Minority Health
Research Personnel
Education
Population
Neoplasms
Open Access
Propensity Score
Segmental Mastectomy
Breast
Breast Neoplasms
Disease-Free Survival

Advanced, Interactive, Image-based Education: Technology and Pedagogy

Richardson, M. L., Shaffer, K., Amini, B. & Spittler, N. L. J., Mar 1 2020, In : Current Problems in Diagnostic Radiology. 49, 2, p. 74-81 8 p.

Research output: Contribution to journalReview article

Teaching
Students
Technology
Education
Radiology

Advances in endovascular neuro-oncology: Endovascular selective intra-arterial (ESIA) infusion of targeted biologic therapy for brain tumors

Srinivasan, V. M., Lang, F. F., Chen, S. R., Chen, M. M., Gumin, J., Johnson, J., Burkhardt, J. K. & Kan, P., Feb 1 2020, In : Journal of neurointerventional surgery. 12, 2, p. 197-203 7 p.

Research output: Contribution to journalReview article

Intra Arterial Infusions
Biological Therapy
Brain Neoplasms
temozolomide
Technology

Adverse Events of Novel Therapies for Hematologic Malignancies: What Emergency Physicians Should Know

Shah, M., Rajha, E., DiNardo, C., Muckey, E., Wierda, W. G. & Yeung, S. C. J., Feb 2020, In : Annals of emergency medicine. 75, 2, p. 264-286 23 p.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Emergencies
Physicians
Antigen Receptors
Emergency Medicine

A functional model for classifying metastatic lesions integrating scans and biomarkers

Wang, Y., Hu, J., Ng, C. S. & Hobbs, B. P., Jan 1 2020, In : Statistical Methods in Medical Research. 29, 1, p. 137-150 14 p.

Research output: Contribution to journalArticle

Functional Model
Biomarkers
Perfusion
Computed Tomography
Liver

Age at first intercourse, number of partners and sexually transmitted infection prevalence among Danish, Norwegian and Swedish women: estimates and trends from nationally representative cross-sectional surveys of more than 100 000 women

Hansen, B. T., Kjær, S. K., Arnheim-Dahlström, L., Liaw, K. L., Juul, K. E., Thomsen, L. T., Frederiksen, K., Elfström, K. M., Munk, C. & Nygård, M., Feb 1 2020, In : Acta Obstetricia et Gynecologica Scandinavica. 99, 2, p. 175-185 11 p.

Research output: Contribution to journalArticle

Coitus
Sexually Transmitted Diseases
Denmark
Norway
Sweden

A Limited-Versus-Extensive Staging Strategy for Small Cell Prostate Cancer

Syed, S., Basourakos, S. P., Ali, F. S., Garcia, J. L., Zurita-Saavedra, A. & Gong, Z., Feb 1 2020, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 43, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Prostate-Specific Antigen
Neoplasm Metastasis
Survival
Small Cell Lung Carcinoma

ALKATI interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma

Xu, B. S., Chen, H. Y., Que, Y., Xiao, W., Zeng, M. S. & Zhang, X., Jan 2 2020, In : Oncogene. 39, 1, p. 151-163 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Sarcoma
Stem Cells
Cell Nucleus
Disease-Free Survival
1 Citation (Scopus)

Allogeneic haemopoietic transplantation for acute myeloid leukaemia in second complete remission: a registry report by the Acute Leukaemia Working Party of the EBMT

Gilleece, M. H., Labopin, M., Savani, B. N., Yakoub-Agha, I., Socié, G., Gedde-Dahl, T., Blaise, D., Byrne, J. L., Craddock, C., Cornelissen, J. J., Arcese, W., Forcade, E., Crawley, C., Polge, E., Mohty, M. & Nagler, A., Jan 1 2020, In : Leukemia. 34, 1, p. 87-99 13 p.

Research output: Contribution to journalArticle

Homologous Transplantation
Acute Myeloid Leukemia
Registries
Leukemia
Transplants

Allogeneic hematopoietic stem cell transplantation with fludarabine, busulfan, and thiotepa conditioning is associated with favorable outcomes in myelofibrosis

Shouval, R., Vega, Y., Fein, J. A., Danylesko, I., Shem Tov, N., Yerushalmi, R., Sobas, M., Czyż, A., Nagler, A. & Shimoni, A., Jan 1 2020, In : Bone marrow transplantation. 55, 1, p. 147-156 10 p.

Research output: Contribution to journalArticle

Thiotepa
Busulfan
Primary Myelofibrosis
Hematopoietic Stem Cell Transplantation
Disease-Free Survival

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells

Hsu, Y. A., Chang, C. Y., Lan, J. L., Li, J. P., Lin, H. J., Chen, C. S., Wan, L. & Liu, F. T., Jan 15 2020, In : Journal of biomedical science. 27, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Galectins
Pulmonary Fibrosis
Bleomycin
Fibroblasts
Cells

AMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation

Wang, Y. N., Lu, Y. X., Liu, J., Jin, Y., Bi, H. C., Zhao, Q., Liu, Z. X., Li, Y. Q., Hu, J. J., Sheng, H., Jiang, Y. M., Zhang, C., Tian, F., Chen, Y., Pan, Z. Z., Chen, G., Zeng, Z. L., Liu, K. Y., Ogasawara, M., Yun, J. P. & 8 others, Ju, H. Q., Feng, J. X., Xie, D., Gao, S., Jia, W. H., Kopetz, S., Xu, R. H. & Wang, F., Jan 16 2020, In : Oncogene. 39, 3, p. 637-650 14 p.

Research output: Contribution to journalArticle

Open Access
Physiological Stress
Glutathione Reductase
Colorectal Neoplasms
Phosphorylation
oxaliplatin

An adaptive test for meta-analysis of rare variant association studies

Yang, T., Kim, J., Wu, C., Ma, Y., Wei, P. & Pan, W., Jan 1 2020, In : Genetic epidemiology. 44, 1, p. 104-116 13 p.

Research output: Contribution to journalArticle

Meta-Analysis
Exome
National Heart, Lung, and Blood Institute (U.S.)
Coronary Artery Disease
Triglycerides

An adipose tissue galectin controls endothelial cell function via preferential recognition of 3-fucosylated glycans

Maller, S. M., Cagnoni, A. J., Bannoud, N., Sigaut, L., Pérez Sáez, J. M., Pietrasanta, L. I., Yang, R. Y., Liu, F. T., Croci, D. O., Di Lella, S., Sundblad, V., Rabinovich, G. A. & Mariño, K. V., Jan 1 2020, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 1, p. 735-753 19 p.

Research output: Contribution to journalArticle

Open Access
Galectins
Endothelial cells
Polysaccharides
Adipose Tissue
Endothelial Cells

Androgen receptor reverses the oncometabolite R-2-hydroxyglutarate-induced prostate cancer cell invasion via suppressing the circRNA-51217/miRNA-646/TGFβ1/p-Smad2/3 signaling

Xu, H., Sun, Y., You, B., Huang, C. P., Ye, D. & Chang, C., Mar 1 2020, In : Cancer Letters. 472, p. 151-164 14 p.

Research output: Contribution to journalArticle

Open Access
Androgen Receptors
MicroRNAs
Prostatic Neoplasms
Isocitrate Dehydrogenase
Mutation

An international multicenter retrospective analysis of patients with extranodal marginal zone lymphoma and histologically confirmed central nervous system and dural involvement

Sunderland, A. J., Steiner, R. E., Al Zahrani, M., Pinnix, C. C., Dabaja, B. S., Gunther, J. R., Nastoupil, L. J., Jerkeman, M., Joske, D., Cull, G., El-Galaly, T., Villa, D. & Cheah, C. Y., Jan 1 2020, In : Cancer medicine. 9, 2, p. 663-670 8 p.

Research output: Contribution to journalArticle

Open Access
Lymphoma
Central Nervous System
Multicenter Studies
Survival Rate
Retrospective Studies
5 Citations (Scopus)

An inverse association between the Mediterranean diet and bladder cancer risk: a pooled analysis of 13 cohort studies

Witlox, W. J. A., van Osch, F. H. M., Brinkman, M., Jochems, S., Goossens, M. E., Weiderpass, E., White, E., van den Brandt, P. A., Giles, G. G., Milne, R. L., Huybrechts, I., Adami, H. O., Bueno-de-Mesquita, B., Wesselius, A. & Zeegers, M. P., Feb 1 2020, In : European Journal of Nutrition. 59, 1, p. 287-296 10 p.

Research output: Contribution to journalArticle

Mediterranean Diet
Urinary Bladder Neoplasms
Cohort Studies
Diet
Carcinogenesis

A nomogram to predict survival of patients with intermediate-stage hepatocellular carcinoma after transarterial chemoembolization combined with microwave ablation

Ni, J. Y., Fang, Z. T., Sun, H. L., An, C., Huang, Z. M., Zhang, T. Q., Jiang, X. Y., Chen, Y. T., Xu, L. F. & Huang, J. H., Jan 1 2020, (Accepted/In press) In : European Radiology.

Research output: Contribution to journalArticle

Nomograms
Microwaves
Hepatocellular Carcinoma
Survival
Confidence Intervals

A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice

Mattiske, D., Behringer, R. R., Overbeek, P. A. & Pask, A. J., Mar 1 2020, In : Differentiation. 112, p. 1-6 6 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Fertility
Embryonic Development
Ephrins
Urogenital System

A novel nomogram to predict the local tumor progression after microwave ablation in patients with early-stage hepatocellular carcinoma: A tool in prediction of successful ablation

An, C., Wu, S., Huang, Z., Ni, J., Zuo, M., Gu, Y., Zhang, T. & Huang, J., Jan 1 2020, In : Cancer medicine. 9, 1, p. 104-115 12 p.

Research output: Contribution to journalArticle

Open Access
Nomograms
Microwaves
Hepatocellular Carcinoma
Neoplasms
Tomography

A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway

Hsieh, C. L., Huang, H. S., Chen, K. C., Saka, T., Chiang, C. Y., Chung, L. W. K. & Sung, S. Y., Jan 1 2020, In : Molecular cancer therapeutics. 19, 1, p. 101-111 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Castration
Autophagy
Prostatic Neoplasms
Cell Death

A novel treatment strategy using indocyanine green for transarterial chemoembolization in BCLC stage C hepatocellular carcinoma

Mei, J., Li, S. H., Wang, Q. X., Zhong, X. P., Lu, L. H., Kan, A., Wei, W. & Guo, R. P., Jan 1 2020, In : Cancer medicine. 9, 1, p. 62-76 15 p.

Research output: Contribution to journalArticle

Open Access
Indocyanine Green
Liver Neoplasms
Hepatocellular Carcinoma
Survival
Ethiodized Oil
1 Citation (Scopus)

Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Sanikini, H., Muller, D. C., Sophiea, M., Rinaldi, S., Agudo, A., Duell, E. J., Weiderpass, E., Overvad, K., Tjønneland, A., Halkjær, J., Boutron-Ruault, M. C., Carbonnel, F., Cervenka, I., Boeing, H., Kaaks, R., Kühn, T., Trichopoulou, A., Martimianaki, G., Karakatsani, A., Pala, V. & 20 others, Palli, D., Mattiello, A., Tumino, R., Sacerdote, C., Skeie, G., Rylander, C., Chirlaque López, M. D., Sánchez, M. J., Ardanaz, E., Regnér, S., Stocks, T., Bueno-de-Mesquita, B., Vermeulen, R. C. H., Aune, D., Tong, T. Y. N., Kliemann, N., Murphy, N., Chadeau-Hyam, M., Gunter, M. J. & Cross, A. J., Feb 15 2020, In : International Journal of Cancer. 146, 4, p. 929-942 14 p.

Research output: Contribution to journalArticle

Open Access
Esophageal Neoplasms
Stomach Neoplasms
Confidence Intervals
Waist-Hip Ratio
Neoplasms

Antifibrotic and tumor microenvironment modulating effect of date palm fruit (Phoenix dactylifera L.) extracts in pancreatic cancer

Al Alawi, R., Alhamdani, M. S. S., Hoheisel, J. D. & Baqi, Y., Jan 2020, In : Biomedicine and Pharmacotherapy. 121, 109522.

Research output: Contribution to journalArticle

Open Access
Pancreatic Stellate Cells
Tumor Microenvironment
Pancreatic Neoplasms
Acetone
Ethanol
Angelica sinensis
liver failure
cyclodextrins
Liver Failure
Cyclodextrins

An update on fertility preservation strategies for women with cancer

Campbell, S. B. & Woodard, T. L., Jan 2020, In : Gynecologic oncology. 156, 1, p. 3-5 3 p.

Research output: Contribution to journalEditorial

APAatlas: decoding alternative polyadenylation across human tissues

Hong, W., Ruan, H., Zhang, Z., Ye, Y., Liu, Y., Li, S., Jing, Y., Zhang, H., Diao, L., Liang, H. & Han, L., Jan 8 2020, In : Nucleic acids research. 48, D1, p. D34-D39

Research output: Contribution to journalArticle

Open Access
Polyadenylation
Databases
RNA
RNA Isoforms
Organ Specificity
1 Citation (Scopus)

A phase 1 trial of alisertib and romidepsin for relapsed/refractory aggressive B-cell and T-cell lymphomas

Strati, P., Nastoupil, L. J., Davis, R. E., Fayad, L. E., Fowler, N., Hagemeister, F. B., Kwak, L., Oki, Y., Wang, M., Westin, J., Ruben, C. E., Wesson, E. T., Piekarz, R., Fanale, M. A. & Lee, H. J., Jan 1 2020, In : Haematologica. 105, 1, p. E26-E28

Research output: Contribution to journalLetter

Open Access

A phase 3 randomized, open-label, multicenter trial for safety and efficacy of combined trabectedin and pegylated liposomal doxorubicin therapy for recurrent ovarian cancer

Monk, B. J., Herzog, T. J., Wang, G., Triantos, S., Maul, S., Knoblauch, R., McGowan, T., Shalaby, W. S. W. & Coleman, R. L., Jan 1 2020, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journalArticle

trabectedin
Ovarian Neoplasms
Multicenter Studies
Safety
Platinum

A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma

van den Bent, M., Azaro, A., De Vos, F., Sepulveda, J., Yung, W. K. A., Wen, P. Y., Lassman, A. B., Joerger, M., Tabatabai, G., Rodon, J., Tiedt, R., Zhao, S., Kirsilae, T., Cheng, Y., Vicente, S., Balbin, O. A., Zhang, H. & Wick, W., Jan 1 2020, In : Journal of neuro-oncology. 146, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Multicenter Studies
Phosphoric Monoester Hydrolases
Maximum Tolerated Dose
Fatigue

A phase II study of addition of pracinostat to a hypomethylating agent in patients with myelodysplastic syndromes who have not responded to previous hypomethylating agent therapy

Yalniz, F. F., Berdeja, J. G., Maris, M. B., Lyons, R. M., Reeves, J. A., Essell, J. H., Patel, P., Sekeres, M., Hughes, A., Mappa, S. & Garcia-Manero, G., Feb 1 2020, In : British Journal of Haematology. 188, 3, p. 404-412 9 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Proxy
Therapeutics
Bone Marrow
Histone Deacetylase Inhibitors

APOBEC-mediated DNA alterations: A possible new mechanism of carcinogenesis in EBV-positive gastric cancer

Bobrovnitchaia, I., Valieris, R., Drummond, R. D., Lima, J. P., Freitas, H. C., Bartelli, T. F., de Amorim, M. G., Nunes, D. N., Dias-Neto, E. & da Silva, I. T., Jan 1 2020, In : International Journal of Cancer. 146, 1, p. 181-191 11 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Stomach Neoplasms
Carcinogenesis
Mutation
DNA

Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma in vivo

Tsai, J. J., Chen, J. H., Chen, C. H., Chung, J. G. & Hsu, F. T., Feb 1 2020, In : Environmental Toxicology. 35, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
apoptosis
tumor
Tumors
Hepatocellular Carcinoma

Application of Trifluoroacetic Acid as a Theranostic Agent for Chemical Ablation of Solid Tissue

Einstein, S. A., Thompson, E. A., Guo, C., Whitley, E. M., Bankson, J. A. & Cressman, E. N. K., Jan 2020, In : Journal of Vascular and Interventional Radiology. 31, 1, p. 169-175 7 p.

Research output: Contribution to journalArticle

Trifluoroacetic Acid
Theranostic Nanomedicine
Fluorine
Liver
Fluorescence Microscopy

A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort

Ohwada, C., Sakaida, E., Igarashi, A., Kobayashi, T., Doki, N., Mori, T., Kato, J., Koda, Y., Kanamori, H., Tanaka, M., Tachibana, T., Fujisawa, S., Nakajima, Y., Numata, A., Toyosaki, M., Aoyama, Y., Onizuka, M., Hagihara, M., Koyama, S., Kanda, Y. & 9 others, Nakasone, H., Shimizu, H., Kato, S., Watanabe, R., Shono, K., Sakai, R., Saito, T., Nakaseko, C. & Okamoto, S., Jan 2020, In : Biology of Blood and Marrow Transplantation. 26, 1, p. 162-170 9 p.

Research output: Contribution to journalArticle

National Institutes of Health (U.S.)
Graft vs Host Disease
Observation
Survival
Incidence

A Randomized-Controlled Phase 2 Study of the MET Antibody Emibetuzumab in Combination with Erlotinib as First-Line Treatment for EGFR Mutation–Positive NSCLC Patients

Scagliotti, G., Moro-Sibilot, D., Kollmeier, J., Favaretto, A., Cho, E. K., Grosch, H., Kimmich, M., Girard, N., Tsai, C. M., Hsia, T. C., Brighenti, M., Schumann, C., Wang, X. A., Wijayawardana, S. R., Gruver, A. M., Wallin, J., Mansouri, K., Wacheck, V. & Chang, G. C., Jan 2020, In : Journal of Thoracic Oncology. 15, 1, p. 80-90 11 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Antibodies
Disease-Free Survival
Therapeutics
Confidence Intervals

ARID1A deficiency and immune checkpoint blockade therapy: From mechanisms to clinical application

Hu, G., Tu, W., Yang, L., Peng, G. & Yang, L., Mar 31 2020, In : Cancer Letters. 473, p. 148-155 8 p.

Research output: Contribution to journalShort survey

Microsatellite Instability
Chromatin Assembly and Disassembly
Tumor Burden
Neoplasms
Cell Death

A risk-based modeling approach for radiation therapy treatment planning under tumor shrinkage uncertainty

Lim, G. J., Kardar, L., Ebrahimi, S. & Cao, W., Jan 1 2020, In : European Journal of Operational Research. 280, 1, p. 266-278 13 p.

Research output: Contribution to journalArticle

Radiation Therapy
Radiotherapy
Shrinkage
Tumors
Tumor

A role for peroxiredoxins in H2O2- and MEKK-dependent activation of the p38 signaling pathway

Barata, A. G. & Dick, T. P., Jan 2020, In : Redox Biology. 28, 101340.

Research output: Contribution to journalArticle

Open Access
Peroxiredoxins
MAP Kinase Kinase Kinases
p38 Mitogen-Activated Protein Kinases
Chemical activation
Drosophila

Artificial intelligence applications in upper gastrointestinal cancers – Authors' reply

Luo, H., Li, C., He, L., Wang, Z. & Xu, R. H., Jan 2020, In : The lancet oncology. 21, 1, p. e5

Research output: Contribution to journalLetter

Open Access
Neoadjuvant Therapy
Stomach Neoplasms

A solution to the dilution: The role for biomarkers in advanced ovarian cancer

Handley, K. F. & Sood, A. K., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 9-10 2 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers

Assessment of Progression-Free Survival as a Surrogate End Point of Overall Survival in First-Line Treatment of Ovarian Cancer: A Systematic Review and Meta-analysis

Gynecologic Cancer InterGroup (GCIG) Meta-analysis Committee, Jan 3 2020, In : JAMA Network Open. 3, 1, p. e1918939

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Disease-Free Survival
Meta-Analysis
Biomarkers
Survival