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2020

A solution to the dilution: The role for biomarkers in advanced ovarian cancer

Handley, K. F. & Sood, A. K., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 9-10 2 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers

Can stress promote the pathophysiology of brain metastases? A critical review of biobehavioral mechanisms

Seiler, A., Sood, A. K., Jenewein, J. & Fagundes, C. P., Jan 1 2020, (Accepted/In press) In : Brain, behavior, and immunity.

Research output: Contribution to journalReview article

Neoplasm Metastasis
Brain
Neoplasms
Cellular Microenvironment
Tumor Microenvironment

Clinical and biological significance of EZH2 expression in endometrial cancer

Roh, J. W., Choi, J. E., Han, H. D., Hu, W., Matsuo, K., Nishimura, M., Lee, J. S., Kwon, S. Y., Cho, C. H., Kim, J., Coleman, R. L., Lopez-Bernstein, G. & Sood, A. K., Feb 1 2020, In : Cancer Biology and Therapy. 21, 2, p. 147-156 10 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Taxoids
Small Interfering RNA
Apoptosis
Neoplasms

GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma

El-Arabey, A. A., Denizli, M., Kanlikilicer, P., Bayraktar, R., Ivan, C., Rashed, M., Kabil, N., Ozpolat, B., Calin, G. A., Salama, S. A., Abd-Allah, A. R., Sood, A. K. & Lopez-Berestein, G., Apr 2020, In : Cellular Signalling. 68, 109539.

Research output: Contribution to journalArticle

Open Access
Macrophages
Carcinoma
Neoplasms
Ovarian Neoplasms
Cell Line

Pan-cancer clinical and molecular analysis of racial disparities

Lara, O. D., Wang, Y., Asare, A., Xu, T., Chiu, H. S., Liu, Y., Hu, W., Sumazin, P., Uppal, S., Zhang, L., Rauh-Hain, J. A. & Sood, A. K., Feb 15 2020, In : Cancer. 126, 4, p. 800-807 8 p.

Research output: Contribution to journalArticle

African Americans
Neoplasms
Databases
Epigenomics
MicroRNAs

Predictors of survival trajectories among women with epithelial ovarian cancer

Peres, L. C., Sinha, S., Townsend, M. K., Fridley, B. L., Karlan, B. Y., Lutgendorf, S. K., Shinn, E., Sood, A. K. & Tworoger, S. S., Feb 2020, In : Gynecologic oncology. 156, 2, p. 459-466 8 p.

Research output: Contribution to journalArticle

Survival
Mortality
Carcinoma
Ovarian Neoplasms
SEER Program
2019

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-2 regulates TP53-dependent paclitaxel sensitivity in ovarian and breast cancers

Yang, H., Shu, Z., Jiang, Y., Mao, W., Pang, L., Redwood, A., Jeter-Jones, S. L., Jennings, N. B., Ornelas, A., Zhou, J., Rodriguez-Aguayo, C., Bartholomeusz, G., Iles, L. K. R., Zacharias, N. M., Millward, S. W., Lopez-Berestein, G., Le, X. F., Ahmed, A. A., Piwnica-Worms, H., Sood, A. K. & 2 others, Bast, R. C. & Lu, Z., Sep 15 2019, In : Clinical Cancer Research. 25, 18, p. 5702-5716 15 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Paclitaxel
Fructose
Ovarian Neoplasms
Breast Neoplasms
1 Citation (Scopus)

Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53-altered tumors

Gunaratne, P. H., Pan, Y., Rao, A. K., Lin, C., Hernandez-Herrera, A., Liang, K., Rait, A. S., Venkatanarayan, A., Benham, A. L., Rubab, F., Kim, S. S., Rajapakshe, K., Chan, C. K., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Rowat, A. C., Coarfa, C., Pirollo, K. F., Flores, E. R. & 1 others, Chang, E. H., Jul 15 2019, In : Cancer. 125, 14, p. 2409-2422 14 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Neoplasms
B-Cell Lymphoma
Therapeutics
Heterografts
3 Citations (Scopus)

Advancing drug development in gynecologic malignancies

Beaver, J. A., Coleman, R. L., Arend, R. C., Armstrong, D. K., Bala, S., Mills, G. B., Sood, A. K. & Herzog, T. J., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4874-4880 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Pharmaceutical Preparations
Neoplasms
Drug Approval
Education
2 Citations (Scopus)

Anti-Angiogenesis Therapy in Ovarian Cancer: Which Patient is It Most Likely to Benefit?

Chelariu-Raicu, A., Coleman, R. L. & Sood, A. K., Jul 16 2019, In : Oncology (Williston Park, N.Y.). 33, 7

Research output: Contribution to journalArticle

Ovarian Neoplasms
Drug Approval
Combination Drug Therapy
Colorectal Neoplasms
Therapeutics

A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

Xu, X., Wang, Y., Mojumdar, K., Zhou, Z., Jeong, K. J., Mangala, L. S., Yu, S., Tsang, Y. H., Rodriguez-Aguayo, C., Lu, Y., Lopez-Berestein, G., Sood, A. K., Mills, G. B. & Liang, H., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5343-5356 14 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Cell Proliferation
Apoptosis
RNA Editing
Neoplasms

Author Correction: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2 (Nature, (2014), 512, 7515, (431-435), 10.1038/nature13375)

Krzeszinski, J. Y., Wei, W., Huynh, H. D., Jin, Z., Wang, X., Chang, T. C., Xie, X. J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Jun 20 2019, In : Nature. 570, 7761, p. E51

Research output: Contribution to journalComment/debate

Open Access
Osteogenesis
Osteoporosis
History
Neoplasm Metastasis
Bone and Bones
1 Citation (Scopus)

Chromosomal instability in tumor initiation and development

Bach, D. H., Zhang, W. & Sood, A. K., Aug 15 2019, In : Cancer research. 79, 16, p. 3995-4002 8 p.

Research output: Contribution to journalReview article

Chromosomal Instability
Neoplasms
Genomic Instability
Carcinogenesis
Neoplasm Metastasis
45 Citations (Scopus)

Circular RNAs in Cancer

Bach, D. H., Lee, S. K. & Sood, A. K., Jun 7 2019, In : Molecular Therapy - Nucleic Acids. 16, p. 118-129 12 p.

Research output: Contribution to journalReview article

Open Access
Neoplasms
RNA Precursors
Porifera
Tumor Biomarkers
Computational Biology
1 Citation (Scopus)

Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention

Shi, S., Li, T., Wen, X., Wu, S. Y., Xiong, C., Zhao, J., Lincha, V. R., Chow, D. S., Liu, Y., Sood, A. K. & Li, C., Jan 1 2019, In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

Exosomes
Positron emission tomography
Positron-Emission Tomography
Tumors
Copper

Corrigendum: FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair

Park, Y. Y., Jung, S. Y., Jennings, N. B., Rodriguez-Aguayo, C., Peng, G., Lee, S. R., Kim, S. B., Kim, K., Leem, S. H., Lin, S. Y., Lopez-Berestein, G., Sood, A. K. & Lee, J. S., Jul 20 2019, In : Carcinogenesis. 40, 7, 1 p.

Research output: Contribution to journalComment/debate

Open Access
DNA Repair
Breast Neoplasms
corrigendum
4 Citations (Scopus)

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference

Bast, R. C., Matulonis, U. A., Sood, A. K., Ahmed, A. A., Amobi, A. E., Balkwill, F. R., Wielgos-Bonvallet, M., Bowtell, D. D. L., Brenton, J. D., Brugge, J. S., Coleman, R. L., Draetta, G. F., Doberstein, K., Drapkin, R. I., Eckert, M. A., Edwards, R. P., Elias, K. M., Ennis, D., Futreal, A., Gershenson, D. M. & 23 others, Greenberg, R. A., Huntsman, D. G., Ji, J. X. Y., Kohn, E. C., Iavarone, C., Lengyel, E. R., Levine, D. A., Lord, C. J., Lu, Z., Mills, G. B., Modugno, F., Nelson, B. H., Odunsi, K., Pilsworth, J. A., Rottapel, R. K., Powell, D. J., Shen, L., Shih, I. M., Spriggs, D. R., Walton, J., Zhang, K., Zhang, R. & Zou, L., Jun 15 2019, In : Cancer. 125, 12, p. 1963-1972 10 p.

Research output: Contribution to journalComment/debate

Ovarian Neoplasms
Poly Adenosine Diphosphate Ribose
Drug Therapy
Platinum
Drug Resistance

Diagnosis-shift between low-grade serous ovarian cancer and serous borderline ovarian tumor: A population-based study

Matsuo, K., Machida, H., Grubbs, B. H., Matsuzaki, S., Klar, M., Roman, L. D., Sood, A. K. & Gershenson, D. M., Jan 1 2019, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Population
Neoplasms
SEER Program
Survival

Effects of Gastrointestinal-Type Chemotherapy in Women With Ovarian Mucinous Carcinoma

Kurnit, K. C., Sinno, A. K., Fellman, B. M., Varghese, A., Stone, R., Sood, A. K., Gershenson, D. M., Schmeler, K. M., Malpica, A., Fader, A. N. & Frumovitz, M., Dec 1 2019, In : Obstetrics and gynecology. 134, 6, p. 1253-1259 7 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Drug Therapy
oxaliplatin
irinotecan
Survival
3 Citations (Scopus)

EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis

An, J., Du, Y., Fan, X., Wang, Y., Ivan, C., Zhang, X. G., Sood, A. K., An, Z. & Zhang, N., Mar 21 2019, In : Oncogene. 38, 12, p. 2123-2134 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Cell Movement
Heterografts

Erratum: Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers (Science Translational Medicine DOI: 10.1126/scitranslmed.aao4307)

Nilsson, M. B., Sun, H., Diao, L., Tong, P., Liu, D., Li, L., Fan, Y., Poteete, A., Lim, S. O., Howells, K., Haddad, V., Gomez, D., Tran, H., Pena, G. A., Sequist, L. V., Yang, J. C., Wang, J., Kim, E. S., Herbst, R., Lee, J. J. & 5 others, Hong, W. K., Wistuba, I., Hung, M. C., Sood, A. K. & Heymach, J. V., May 22 2019, In : Science Translational Medicine. 11, 493, eaax9987.

Research output: Contribution to journalComment/debate

Translational Medical Research
Hormones
Research
1 Citation (Scopus)

Erratum: The Immune Landscape of Cancer (Immunity (2018) 48(4) (812–830.e14), (S1074761318301213), (10.1016/j.immuni.2018.03.023))

The Cancer Genome Atlas Research Network, Aug 20 2019, In : Immunity. 51, 2, p. 411-412 2 p.

Research output: Contribution to journalComment/debate

Open Access
Immunity
Names
Genes
Neoplasms
Research Design
18 Citations (Scopus)

Exploring and comparing adverse events between PARP inhibitors

LaFargue, C. J., Dal Molin, G. Z., Sood, A. K. & Coleman, R., Jan 1 2019, In : The lancet oncology. 20, 1, p. e15-e28

Research output: Contribution to journalReview article

Ovarian Neoplasms
Recombinational DNA Repair
Poisons
United States Food and Drug Administration
Pharmaceutical Preparations
15 Citations (Scopus)

exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids

Murillo, O. D., Thistlethwaite, W., Rozowsky, J., Subramanian, S. L., Lucero, R., Shah, N., Jackson, A. R., Srinivasan, S., Chung, A., Laurent, C. D., Kitchen, R. R., Galeev, T., Warrell, J., Diao, J. A., Welsh, J. A., Hanspers, K., Riutta, A., Burgstaller-Muehlbacher, S., Shah, R. V., Yeri, A. & 38 others, Jenkins, L. M., Ahsen, M. E., Cordon-Cardo, C., Dogra, N., Gifford, S. M., Smith, J. T., Stolovitzky, G., Tewari, A. K., Wunsch, B. H., Yadav, K. K., Danielson, K. M., Filant, J., Moeller, C., Nejad, P., Paul, A., Simonson, B., Wong, D. K., Zhang, X., Balaj, L., Gandhi, R., Sood, A. K., Alexander, R. P., Wang, L., Wu, C., Wong, D. T. W., Galas, D. J., Van Keuren-Jensen, K., Patel, T., Jones, J. C., Das, S., Cheung, K. H., Pico, A. R., Su, A. I., Raffai, R. L., Laurent, L. C., Roth, M. E., Gerstein, M. B. & Milosavljevic, A., Apr 4 2019, In : Cell. 177, 2, p. 463-477.e15

Research output: Contribution to journalArticle

Atlases
RNA
Deconvolution
Saliva
Urine

GnRH-R-Targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition

Ma, S., Pradeep, S., Villar-Prados, A., Wen, Y., Bayraktar, E., Mangala, L. S., Kim, M. S., Wu, S. Y., Hu, W., Rodriguez-Aguayo, C., Leuschner, C., Liang, X., Ram, P. T., Schlacher, K., Coleman, R. L. & Sood, A. K., Jan 1 2019, In : Molecular cancer therapeutics. 18, 5, p. 969-979 11 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Ovarian Neoplasms
Peptides
Protein Array Analysis
Comet Assay
2 Citations (Scopus)

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S., Sabnis, N., Kong, X., Yang, X., Lopez-Berestein, G., Lacko, A. G. & Sood, A. K., Aug 15 2019, In : Oncogene. 38, 33, p. 6095-6108 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Ovarian Neoplasms
Neoplasms
CD36 Antigens
Vascular Endothelial Growth Factor A

Long non-coding RNAs in ovarian cancer: expression profile and functional spectrum

Oncul, S., Amero, P., Rodriguez-Aguayo, C., Calin, G. A., Sood, A. K. & Lopez-Berestein, G., Jan 1 2019, (Accepted/In press) In : RNA Biology.

Research output: Contribution to journalReview article

Long Noncoding RNA
Ovarian Neoplasms
Ovary
Immune System
Neoplasms

Mechanisms of nuclear content loading to exosomes

Yokoi, A., Villar-Prados, A., Oliphint, P. A., Zhang, J., Song, X., DeHoff, P., Morey, R., Liu, J., Roszik, J., Clise-Dwyer, K., Burks, J. K., O'Halloran, T. J., Laurent, L. C. & Sood, A. K., Nov 20 2019, In : Science advances. 5, 11, eaax8849.

Research output: Contribution to journalArticle

Open Access
cancer
deoxyribonucleic acid
markers
cargo
cytometry

miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

Parashar, D., Geethadevi, A., Aure, M. R., Mishra, J., George, J., Chen, C., Mishra, M. K., Tahiri, A., Zhao, W., Nair, B., Lu, Y., Mangala, L. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Camara, A. K. S., Liang, M., Rader, J. S., Ramchandran, R., You, M., Sood, A. K. & 4 others, Kristensen, V. N., Mills, G. B., Pradeep, S. & Chaluvally-Raghavan, P., Dec 24 2019, In : Cell Reports. 29, 13, p. 4389-4406.e10

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Genes
Autocrine Communication
MicroRNAs
Transcriptional Activation
1 Citation (Scopus)

Mucinous borderline ovarian tumor versus invasive well-differentiated mucinous ovarian cancer: Difference in characteristics and outcomes

Matsuo, K., Machida, H., Mandelbaum, R. S., Grubbs, B. H., Roman, L. D., Sood, A. K. & Gershenson, D. M., May 1 2019, In : Gynecologic oncology. 153, 2, p. 230-237 8 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Propensity Score
Survival
SEER Program
8 Citations (Scopus)

Ovarian cancer cell-derived lysophosphatidic acid induces glycolytic shift and cancer-associated fibroblast-phenotype in normal and peritumoral fibroblasts

Radhakrishnan, R., Ha, J. H., Jayaraman, M., Liu, J., Moxley, K. M., Isidoro, C., Sood, A. K., Song, Y. S. & Dhanasekaran, D. N., Feb 1 2019, In : Cancer Letters. 442, p. 464-474 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Fibroblasts
Phenotype
Glycolysis
Conditioned Culture Medium

Oxytocin in the tumor microenvironment is associated with lower inflammation and longer survival in advanced epithelial ovarian cancer patients

Cuneo, M. G., Szeto, A., Schrepf, A., Kinner, E. M., Schachner, B. I., Ahmed, R., Thaker, P. H., Goodheart, M., Bender, D., Cole, S. W., McCabe, P. M., Sood, A. K., Lutgendorf, S. K. & Mendez, A. J., Aug 2019, In : Psychoneuroendocrinology. 106, p. 244-251 8 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Oxytocin
Inflammation
Survival
Interleukin-6
3 Citations (Scopus)

Pan-cancer genomic analysis links 3’UTR DNA methylation with increased gene expression in T cells

McGuire, M. H., Herbrich, S. M., Dasari, S. K., Wu, S. Y., Wang, Y., Rupaimoole, R., Lopez-Berestein, G., Baggerly, K. A. & Sood, A. K., May 2019, In : EBioMedicine. 43, p. 127-137 11 p.

Research output: Contribution to journalArticle

Open Access
T-cells
DNA Methylation
Gene expression
T-Lymphocytes
Gene Expression
10 Citations (Scopus)

Performance of the MasSpec pen for rapid diagnosis of Ovarian cancer

Sans, M., Zhang, J., Lin, J. Q., Feider, C. L., Giese, N., Breen, M. T., Sebastian, K., Liu, J., Sood, A. K. & Eberlin, L. S., May 1 2019, In : Clinical chemistry. 65, 5, p. 674-683 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Tissue
Peritoneum
Mass spectrometers
Learning systems
4 Citations (Scopus)

Perineural invasion (PNI) in vulvar carcinoma: A review of 421 cases

Salcedo, M. P., Sood, A. K., dos Reis, R., Ramalingam, P., Chen, C., Frumovitz, M., Jhingran, A., Pitcher, B., Ramirez, P. T. & Schmeler, K. M., Jan 2019, In : Gynecologic oncology. 152, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

Carcinoma
Disease-Free Survival
Lichen Sclerosus et Atrophicus
Survival
Medical Records

Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers

Sa, J. K., Hwang, J. R., Cho, Y. J., Ryu, J. Y., Choi, J. J., Jeong, S. Y., Kim, J., Kim, M. S., Paik, E. S., Lee, Y. Y., Choi, C. H., Kim, T. J., Kim, B. G., Bae, D. S., Lee, Y., Her, N. G., Shin, Y. J., Cho, H. J., Kim, J. Y., Seo, Y. J. & 14 others, Koo, H., Oh, J. W., Lee, T., Kim, H. S., Song, S. Y., Bae, J. S., Park, W. Y., Han, H. D., Ahn, H. J., Sood, A. K., Rabadan, R., Lee, J. K., Nam, D. H. & Lee, J. W., Nov 26 2019, In : Genome biology. 20, 1, 253.

Research output: Contribution to journalArticle

Open Access
pharmacogenomics
tumor
cancer
neoplasms
drug
2 Citations (Scopus)

Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein Brd4

Villar-Prados, A., Wu, S. Y., Court, K. A., Ma, S., LaFargue, C., Chowdhury, M. A., Engelhardt, M. I., Ivan, C., Ram, P. T., Wang, Y., Baggerly, K., Rodriguez-Aguayo, C., Lopez-Berestein, G., Yang, S. M., Maloney, D. J., Yoshioka, M., Strovel, J. W., Roszik, J. & Sood, A. K., Feb 2019, In : Molecular cancer therapeutics. 18, 2, p. 421-436 16 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Small Interfering RNA
Therapeutics
Down-Regulation
Neoplasms
3 Citations (Scopus)

PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer

Hisamatsu, T., McGuire, M., Wu, S. Y., Rupaimoole, R., Pradeep, S., Bayraktar, E., Noh, K., Hu, W., Hansen, J. M., Lyons, Y., Gharpure, K. M., Nagaraja, A. S., Mangala, L. S., Mitamura, T., Rodriguez-Aguayo, C., Eun, Y. G., Rose, J., Bartholomeusz, G., Ivan, C., Lee, J. S. & 5 others, Matsuo, K., Frumovitz, M., Wong, K. K., Lopez-Berestein, G. & Sood, A. K., Jan 2019, In : Molecular cancer therapeutics. 18, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Ovarian Neoplasms
Small Interfering RNA
Platinum
Phosphotransferases
2 Citations (Scopus)

Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene expression

Ramondetta, L. M., Hu, W., Thaker, P. H., Urbauer, D. L., Chisholm, G. B., Westin, S. N., Sun, Y., Ramirez, P. T., Fleming, N., Sahai, S. K., Nick, A. M., Arevalo, J. M. G., Dizon, T., Coleman, R. L., Cole, S. W. & Sood, A. K., Sep 2019, In : Gynecologic oncology. 154, 3, p. 524-530 7 p.

Research output: Contribution to journalArticle

Propranolol
Gene Expression
Drug Therapy
Adrenergic Agents
Therapeutics

Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer

Shuford, S., Wilhelm, C., Rayner, M., Elrod, A., Millard, M., Mattingly, C., Lotstein, A., Smith, A. M., Guo, Q. J., O’Donnell, L., Elder, J., Puls, L., Weroha, S. J., Hou, X., Zanfagnin, V., Nick, A., Stany, M. P., Maxwell, G. L., Conrads, T., Sood, A. K. & 5 others, Orr, D., Holmes, L. M., Gevaert, M., Crosswell, H. E. & DesRochers, T. M., Dec 1 2019, In : Scientific reports. 9, 1, 11153.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Therapeutics
Recurrence
Survival
Population

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis

Rodriguez-Aguayo, C., Bayraktar, E., Ivan, C., Aslan, B., Mai, J., He, G., Mangala, L. S., Jiang, D., Nagaraja, A. S., Ozpolat, B., Chavez-Reyes, A., Ferrari, M., Mitra, R., Siddik, Z. H., Shen, H., Yang, X., Sood, A. K. & Lopez-Berestein, G., Feb 2019, In : EBioMedicine. 40, p. 290-304 15 p.

Research output: Contribution to journalArticle

Dinoprostone
Cisplatin
Ovary
Carcinogenesis
Up-Regulation
1 Citation (Scopus)

Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis

Azam, S. H., Porrello, A., Harrison, E. B., Leslie, P. L., Liu, X., Waugh, T. A., Belanger, A., Mangala, L. S., Lopez-Berestein, G., Wilson, H. L., McCann, J. V., Kim, W. Y., Sood, A. K., Liu, J., Dudley, A. C. & Pecot, C. V., Jun 27 2019, In : Oncogene. 38, 26, p. 5191-5210 20 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Cell Cycle
Endothelial Cells
MicroRNAs
Neoplasm Metastasis
22 Citations (Scopus)

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

Srinivasan, S., Yeri, A., Cheah, P. S., Chung, A., Danielson, K., De Hoff, P., Filant, J., Laurent, C. D., Laurent, L. D., Magee, R., Moeller, C., Murthy, V. L., Nejad, P., Paul, A., Rigoutsos, I., Rodosthenous, R., Shah, R. V., Simonson, B., To, C., Wong, D. & 14 others, Yan, I. K., Zhang, X., Balaj, L., Breakefield, X. O., Daaboul, G., Gandhi, R., Lapidus, J., Londin, E., Patel, T., Raffai, R. L., Sood, A. K., Alexander, R. P., Das, S. & Laurent, L. C., Apr 4 2019, In : Cell. 177, 2, p. 446-462.e16

Research output: Contribution to journalArticle

RNA Sequence Analysis
RNA
MicroRNAs
Research Personnel
Ribonucleoproteins

Social Integration, Marital Status, and Ovarian Cancer Risk: A 20-Year Prospective Cohort Study

Trudel-Fitzgerald, C., Poole, E. M., Sood, A. K., Okereke, O. I., Kawachi, I., Kubzansky, L. D. & Tworoger, S. S., Nov 1 2019, In : Psychosomatic medicine. 81, 9, p. 833-840 8 p.

Research output: Contribution to journalArticle

Marital Status
Ovarian Neoplasms
Cohort Studies
Prospective Studies
Widowhood
13 Citations (Scopus)

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

The Extracellular RNA Communication Consortium, Apr 4 2019, In : Cell. 177, 2, p. 231-242 12 p.

Research output: Contribution to journalReview article

Open Access
RNA
Technology
Communication
Research
Biomarkers

Tumor core biopsies adequately represent immune microenvironment of high-grade serous carcinoma

Lara, O. D., Krishnan, S., Wang, Z., Corvigno, S., Zhong, Y. P., Lyons, Y., Dood, R., Hu, W., Qi, L., Liu, J., Coleman, R. L., Westin, S. N., Fleming, N. D., Cristini, V., Rao, A., Burks, J. & Sood, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 17589.

Research output: Contribution to journalArticle

Open Access
Carcinoma
Biopsy
Tumor Microenvironment
Neoplasms
Staining and Labeling
2018
72 Citations (Scopus)

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Breast Neoplasms
Atlases
Long Noncoding RNA
Decision Trees
Genome
8 Citations (Scopus)

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

González-González, A., Muñoz-Muela, E., Marchal, J. A., Cara, F. E., Molina, M. P., Cruz-Lozano, M., Jiménez, G., Verma, A., Ramírez, A., Qian, W., Chen, W., Kozielski, A. J., Elemento, O., Martín-Salvago, M. D., Luque, R. J., Rosa-Garrido, C., Landeira, D., Quintana-Romero, M., Rosato, R. R., García, M. A. & 9 others, Ramirez-Tortosa, C. L., Kim, H., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Lorente, J. A., Sánchez-Rovira, P., Chang, J. C. & Granados-Principal, S., Nov 15 2018, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 24, 22, p. 5697-5709 13 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 4
Triple Negative Breast Neoplasms
Survival
Breast Neoplasms
Heterografts
3 Citations (Scopus)

ADH1B promotes mesothelial clearance and ovarian cancer infiltration

Gharpure, K. M., Lara, O. D., Wen, Y., Pradeep, S., LaFargue, C., Ivan, C., Rupaimoole, R., Hu, W., Mangala, L. S., Wu, S. Y., Nagaraja, A. S., Baggerly, K. & Sood, A. K., May 18 2018, In : Oncotarget. 9, 38, p. 25115-25126 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Adjuvant Chemotherapy
Cell Adhesion
Extracellular Matrix
1 Citation (Scopus)

Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens

Nagaraja, A. S., Dood, R. L., Armaiz-Pena, G., Kang, Y., Wu, S. Y., Allen, J. K., Jennings, N. B., Mangala, L. S., Pradeep, S., Lyons, Y., Haemmerle, M., Gharpure, K. M., Sadaoui, N. C., Rodriguez-Aguayo, C., Ivan, C., Wang, Y., Baggerly, K., Ram, P., Lopez-Berestein, G., Liu, J. & 5 others, Mok, S. C., Cohen, L., Lutgendorf, S. K., Cole, S. W. & Sood, A. K., Jun 7 2018, In : JCI Insight. 3, 11

Research output: Contribution to journalArticle

Open Access