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2020
T-Cell Prolymphocytic Leukemia
Pentostatin
4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide
Gene Frequency
Acute Myeloid Leukemia
Mutation
Survival
Leukocyte Count
2019
1 Citation (Scopus)
decitabine
21 Citations (Scopus)

Acute myeloid leukemia, version 3.2019

Tallman, M. S., Wang, E. S., Altman, J. K., Appelbaum, F. R., Bhatt, V. R., Bixby, D., Coutre, S. E., De Lima, M., Fathi, A. T., Fiorella, M., Foran, J. M., Hall, A. C., Jacoby, M., Lancet, J., LeBlanc, T. W., Mannis, G., Marcucci, G., Martin, M. G., Mims, A., O'Donnell, M. R. & 14 others, Olin, R., Peker, D., Perl, A., Pollyea, D. A., Pratz, K., Prebet, T., Ravandi, F., Shami, P. J., Stone, R. M., Strickland, S. A., Wieduwilt, M., Gregory, K. M., Hammond, L. & Ogba, N., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 6, p. 721-749 29 p.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Leukemia
Practice Guidelines
Therapeutics
Guidelines
1 Citation (Scopus)
Acute Promyelocytic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Tretinoin
Leukemia
Bone Marrow Examination
7 Citations (Scopus)

Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs

Jain, P., Kantarjian, H., Boddu, P. C., Nogueras-González, G. M., Verstovsek, S., Garcia-Manero, G., Borthakur, G., Sasaki, K., Kadia, T. M., Sam, P., Ahaneku, H., O’Brien, S., Estrov, Z., Ravandi, F., Jabbour, E. & Cortes, J. E., Mar 26 2019, In : Blood Advances. 3, 6, p. 851-861 11 p.

Research output: Contribution to journalArticle

Open Access
Leukemia, Myeloid, Chronic Phase
Protein-Tyrosine Kinases
Incidence
Confidence Intervals
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
3 Citations (Scopus)

Chromosomal abnormalities and prognosis in NPM1-mutated acute myeloid leukemia: A pooled analysis of individual patient data from nine international cohorts

Angenendt, L., Röllig, C., Montesinos, P., Martínez-Cuadrón, D., Barragan, E., García, R., Botella, C., Martínez, P., Ravandi, F., Kadia, T., Kantarjian, H. M., Cortes, J., Juliusson, G., Lazarevic, V., Höglund, M., Lehmann, S., Recher, C., Pigneux, A., Bertoli, S., Dumas, P. Y. & 25 others, Dombret, H., Preudhomme, C., Micol, J. B., Terré, C., Ráčil, Z., Novák, J., Žák, P., Wei, A. H., Tiong, I. S., Wall, M., Estey, E., Shaw, C., Exeler, R., Wagenführ, L., Stölzel, F., Thiede, C., Stelljes, M., Lenz, G., Mikesch, J. H., Serve, H., Ehninger, G., Berdel, W. E., Kramer, M., Krug, U. & Schliemann, C., Oct 10 2019, In : Journal of Clinical Oncology. 37, 29, p. 2632-2642 11 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Chromosome Aberrations
Karyotype
Cytogenetics
Abnormal Karyotype
13 Citations (Scopus)

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S. K., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 others, Borthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. J. & Tyner, J. W., Dec 1 2019, In : Nature communications. 10, 1, 244.

Research output: Contribution to journalArticle

Open Access
leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors

Clonal Dynamics and Clinical Implications of Post-Remission Clonal Hematopoiesis in Acute Myeloid Leukemia (AML)

Tanaka, T., Morita, K., Wang, F., Little, L., Gumbs, C., Matthews, J., DiNardo, C. D., Kadia, T. M., Ravandi, F., Konopleva, M. Y., Kantarjian, H. M., Champlin, R. E., Garcia-Manero, G., Futreal, P. A. & Takahashi, K., Nov 13 2019, In : Blood. 134, 1, 1 p.

Research output: Contribution to journalArticle

Hematopoiesis
Acute Myeloid Leukemia
Research
Advisory Committees
Actinium
2 Citations (Scopus)
Myelodysplastic Syndromes
Hematopoiesis
Comorbidity
Mutation
Janus Kinase 2

Current and emerging treatments for acute promyelocytic leukemia

Yilmaz, M., Naqvi, K. & Ravandi, F., Nov 2 2019, In : Expert Opinion on Orphan Drugs. 7, 11, p. 453-461 9 p.

Research output: Contribution to journalReview article

Acute Promyelocytic Leukemia
Tretinoin
Therapeutics
Arsenicals
Expert Testimony
3 Citations (Scopus)
Thymoma
Mediastinal Neoplasms
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Flow Cytometry
Lymphocytes
33 Citations (Scopus)
Open Access
Azacitidine
Acute Myeloid Leukemia
Biomarkers
Safety
Bone Marrow
Open Access
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Safety
Imatinib Mesylate
Leukemia, Myeloid, Chronic Phase
Generic Drugs

Emerging drug profile: CPX-351 (vyxeos) in AML

Alfayez, M., Kantarjian, H., Kadia, T., Ravandi-Kashani, F. & Daver, N., Jan 1 2019, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalReview article

Acute Myeloid Leukemia
Pharmaceutical Preparations
Cytarabine
Daunorubicin
Anthracyclines

Exome analysis of treatment-related AML after APL suggests secondary evolution

Wang, T., Jacoby, M. A., Duncavage, E. J., Miller, C. A., Heath, S., Rahme, R., Fenaux, P., Ades, L., Renneville, A., Cassinat, B., Takeshita, A., Asou, N., Miyazaki, Y., Kiyoi, H., Ravandi, F., Westervelt, P., Wartman, L. D. & Welch, J. S., Jun 2019, In : British Journal of Haematology. 185, 5, p. 984-987 4 p.

Research output: Contribution to journalLetter

Exome
Acute Promyelocytic Leukemia
Drug Therapy
1 Citation (Scopus)

FLT3 inhibitor quizartinib (AC220)

Naqvi, K. & Ravandi-Kashani, F., Jul 3 2019, In : Leukemia and Lymphoma. 60, 8, p. 1866-1876 11 p.

Research output: Contribution to journalReview article

Acute Myeloid Leukemia
Mutation
MAP Kinase Kinase Kinases
Recurrence
Phase II Clinical Trials
Residual Neoplasm
Acute Myeloid Leukemia
Transplantation
Transplants
Melphalan
1 Citation (Scopus)
Hematologic Neoplasms
Neoplasms
Germ-Line Mutation
Cytogenetic Analysis
Myelodysplastic Syndromes
1 Citation (Scopus)

How close are we to incorporating measurable residual disease into clinical practice for acute myeloid leukemia?

Short, N. J. & Ravandi, F., Jul 31 2019, In : Haematologica. 104, 8, p. 1532-1541 10 p.

Research output: Contribution to journalReview article

Open Access
Acute Myeloid Leukemia
Leukemia
Residual Neoplasm
Stem Cell Transplantation
Cytogenetics
3 Citations (Scopus)

How I treat Philadelphia chromosome–positive acute lymphoblastic leukemia

Ravandi, F., Jan 10 2019, In : Blood. 133, 2, p. 130-136 7 p.

Research output: Contribution to journalReview article

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Chemotherapy
Tyrosine
Drug Therapy
Disease Eradication
1 Citation (Scopus)
Second Primary Neoplasms
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Incidence
SEER Program
1 Citation (Scopus)
Janus Kinase 2
Acute Myeloid Leukemia
Neoplasms
Primary Myelofibrosis
Mutation
5 Citations (Scopus)
Clonal Evolution
Acute Myeloid Leukemia
Leukemia
Recurrence
Therapeutics
21 Citations (Scopus)

Management of acute promyelocytic leukemia: Updated recommendations from an expert panel of the European LeukemiaNet

Sanz, M. A., Fenaux, P., Tallman, M. S., Estey, E. H., Löwenberg, B., Naoe, T., Lengfelder, E., Döhner, H., Burnett, A. K., Chen, S. J., Mathews, V., Iland, H., Rego, E., Kantarjian, H., Adès, L., Avvisati, G., Montesinos, P., Platzbecker, U., Ravandi, F., Russell, N. H. & 1 others, Lo-Coco, F., Apr 11 2019, In : Blood. 133, 15, p. 1630-1643 14 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Therapeutics
Salvaging
Salvage Therapy
Disease Management
1 Citation (Scopus)

Midostaurin in acute myeloid leukemia: An evidence-based review and patient selection

Abbas, H. A., Alfayez, M., Kadia, T., Ravandi-Kashani, F. & Daver, N., Jan 1 2019, In : Cancer Management and Research. 11, p. 8817-8828 12 p.

Research output: Contribution to journalReview article

Open Access
4'-N-benzoylstaurosporine
Acute Myeloid Leukemia
Patient Selection
Phase III Clinical Trials
Stem Cell Transplantation

Moxetumomab pasudotox for the treatment of relapsed and/or refractory hairy cell leukemia

Abou Dalle, I. & Ravandi-Kashani, F., Sep 2 2019, In : Expert review of hematology. 12, 9, p. 707-714 8 p.

Research output: Contribution to journalArticle

Hairy Cell Leukemia
Purine Nucleosides
Capillary Leak Syndrome
Therapeutics
Drug Labeling
3 Citations (Scopus)
Acute Myeloid Leukemia
Recurrence
Survival
Proteins
Disease-Free Survival
2 Citations (Scopus)

NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy

Montalban-Bravo, G., Kanagal-Shamanna, R., Sasaki, K., Patel, K., Ganan-Gomez, I., Jabbour, E., Kadia, T., Ravandi, F., DiNardo, C., Borthakur, G., Takahashi, K., Konopleva, M., Komrokji, R. S., DeZern, A., Kuzmanovic, T., Maciejewski, J., Pierce, S., Colla, S., Sekeres, M. A., Kantarjian, H. & 2 others, Bueso-Ramos, C. & Garcia-Manero, G., Mar 26 2019, In : Blood Advances. 3, 6, p. 922-933 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Drug Therapy
Mutation
Stem Cell Transplantation
Karyotype
1 Citation (Scopus)
Leukemia, Myeloid, Chronic Phase
Therapeutics
ponatinib
Blood Vessels
Outcome Assessment (Health Care)
8 Citations (Scopus)
Acute Myeloid Leukemia
Recurrence
Mutation
Bone Marrow
Flow Cytometry
1 Citation (Scopus)

Phase 1/2 study of DFP-10917 administered by continuous intravenous infusion in patients with recurrent or refractory acute myeloid leukemia

Kantarjian, H. M., Jabbour, E. J., Garcia-Manero, G., Kadia, T. M., DiNardo, C. D., Daver, N. G., Borthakur, G., Jain, N., Waukau, J. B., Kwari, M. I., Ravandi, F., Anderson, B. D., Iizuka, K., Jin, C., Zhang, C. & Plunkett, W. K., May 15 2019, In : Cancer. 125, 10, p. 1665-1673 9 p.

Research output: Contribution to journalArticle

Isoflurophate
Intravenous Infusions
Acute Myeloid Leukemia
Maximum Tolerated Dose
Diarrhea
6 Citations (Scopus)
Mitogen-Activated Protein Kinase Kinases
Acute Myeloid Leukemia
Extracellular Signal-Regulated MAP Kinases
Myelodysplastic Syndromes
Mitogens
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Recurrence
Survival
2 Citations (Scopus)
Acute Myeloid Leukemia
Alleles
Drug Therapy
Idarubicin
Survival
1 Citation (Scopus)

Quizartinib in the treatment of FLT3-internal-tandem duplication-positive acute myeloid leukemia

Paul, S., Dipippo, A. J., Ravandi, F. & Kadia, T. M., Jan 1 2019, In : Future Oncology. 15, 34, p. 3885-3894 10 p.

Research output: Contribution to journalReview article

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Mutation
Survival
Missense Mutation
11 Citations (Scopus)

Recommendations for the assessment and management of measurable residual disease in adults with acute lymphoblastic leukemia: A consensus of North American experts

Short, N. J., Jabbour, E., Albitar, M., de Lima, M., Gore, L., Jorgensen, J., Logan, A. C., Park, J., Ravandi, F., Shah, B., Radich, J. & Kantarjian, H., Feb 1 2019, In : American journal of hematology. 94, 2, p. 257-265 9 p.

Research output: Contribution to journalReview article

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Therapeutics
Leukemia
Recurrence
Survival
2 Citations (Scopus)

Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome

Benton, C. B., Chien, K. S., Tefferi, A., Rodriguez, J., Ravandi, F., Daver, N., Jabbour, E., Jain, N., Alvarado, Y., Kwari, M., Pierce, S., Maiti, A., Hornbaker, M., Santos, M. A., Martinez, S., Siguero, M., Zblewski, D., Al-Kali, A., Hogan, W. J., Kantarjian, H. & 2 others, Pardanani, A. & Garcia-Manero, G., Feb 1 2019, In : Hematological Oncology. 37, 1, p. 96-102 7 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Acute Myeloid Leukemia
Safety
Appointments and Schedules
trabectedin
Acute Myeloid Leukemia
Drug Therapy
Survival
Induction Chemotherapy
4'-N-benzoylstaurosporine
18 Citations (Scopus)

The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia

Williams, P., Basu, S., Garcia-Manero, G., Hourigan, C. S., Oetjen, K. A., Cortes, J. E., Ravandi, F., Jabbour, E. J., Al-Hamal, Z., Konopleva, M., Ning, J., Xiao, L., Hidalgo Lopez, J., Kornblau, S. M., Andreeff, M., Flores, W., Bueso-Ramos, C., Blando, J., Galera, P., Calvo, K. R. & 5 others, Al-Atrash, G., Allison, J. P., Kantarjian, H. M., Sharma, P. & Daver, N. G., May 1 2019, In : Cancer. 125, 9, p. 1470-1481 12 p.

Research output: Contribution to journalArticle

Open Access
T-Lymphocyte Subsets
Acute Myeloid Leukemia
Ligands
T-Lymphocytes
Bone Marrow
6 Citations (Scopus)

Treatment of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Abou Dalle, I., Jabbour, E. J., Short, N. J. & Ravandi-Kashani, F., Jan 1 2019, In : Current treatment options in oncology. 20, 1, 4.

Research output: Contribution to journalReview article

Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Hematopoietic Stem Cell Transplantation
Therapeutics
5 Citations (Scopus)
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Clinical Trials
Life Expectancy
Interferons
2 Citations (Scopus)
Acute Promyelocytic Leukemia
Intensive Care Units
Morbidity
Intratracheal Intubation
Tretinoin
6 Citations (Scopus)
fms-Like Tyrosine Kinase 3
Acute Myeloid Leukemia
Genotype
Alleles
nucleophosmin